Patents Examined by Natalie Harkaway
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Patent number: 4299837Abstract: Benzimidazole-carbamates endowed wth anthelmintic activity, and substituted in position 5(6) by a diene chain bound to the position 5(6) by an oxygen or sulphur atom optionally oxidized, are described.The processes for their preparation, the intermediates thereof, and their use as anthelmintics are described too.Type: GrantFiled: June 3, 1980Date of Patent: November 10, 1981Assignee: Montedison S.p.A.Inventors: Paolo Piccardi, Giovanni Confalonieri, Lino Da Col, Pier G. Ramella
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Patent number: 4296118Abstract: N-Acylated N-phenyl-aminotetrahydro-2-furanones of tthe formula ##STR1## wherein R represents C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.1 represents C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.2 represents hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.3 represents hydrogen or methyl, with the total number of C atoms of the substituents R, R.sub.1, R.sub.2 and R.sub.3 in the phenyl ring not exceeding the number 8,R.sub.4 represents hydrogen or methyl, whileR.sub.5 represents one of the following groups: an alkylthioalkyl or alkoxyalkyl group having 2 to 5 carbon atoms or an alkoxyalkoxymethyl group having a maximum of 6 carbon atoms, a 2-furanyl or 2-tetrahydrofuranyl group optionally substituted by halogen, a 1,2,4-triazolymethyl group, a 1,2-pyrazolylmethyl group, or a group -CH.sub.2 -OR.sub.6 in which R.sub.6 represents a 5- or 6-membered heterocycle having oxygen as the hetero atom are valuable fungicidal active substances.Type: GrantFiled: August 22, 1980Date of Patent: October 20, 1981Assignee: Ciba-Geigy CorporationInventors: Walter Kunz, Wolfgang Eckhardt, Adolf Hubele
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Patent number: 4261730Abstract: Aromatic acids having the following formula ##STR1## have been found to be effective plant growth regulants especially for the treatment of corn plants.Type: GrantFiled: August 9, 1978Date of Patent: April 14, 1981Assignee: Monsanto CompanyInventors: Frederic G. Bollinger, John J. D'Amico, Dale J. Hansen
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Patent number: 4255576Abstract: The present invention relates to novel 1-azaxanthone derivatives, which are shown by the following formula: ##STR1## wherein m is 1 or 2R'.sub.1 is hydrogen, C.sub.1-6 alkyl, phenyl, C.sub.1-6 alkoxycarbonyl, hydroxy, C.sub.1-4 alkoxy, amino or C.sub.1-3 alkylamino;each of R.sub.2 is independently C.sub.1-6 alkyl, C.sub.1-4 alkoxy, halogen, nitro, hydroxy, carboxy, amino, C.sub.1-3 alkylamino or di(C.sub.1-3 alkyl) amino; orwhen m is 2, the two R.sub.2 groups may be independently as defined above or may form together with adjacent rings carbon atoms the butadienylene group;R.sub.3 is cyano, C.sub.1-6 alkoxycarbonyl, carboxamide, N-C.sub.1-3 alkylcarboxamide or N,N-di(C.sub.1-3 alkyl) carboxamide.The novel derivatives are useful as intermediates for 1-azaxanthone-3-carboxylic acid derivatives having effective antiallergic and bronchodilating activities.Type: GrantFiled: December 18, 1978Date of Patent: March 10, 1981Assignee: Takeda Chemical Industries, Ltd.Inventors: Akira Nohara, Hirosada Sugihara, Kiyoshi Ukawa
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Patent number: 4254267Abstract: Hypotensive activity is exhibited by compounds having the formula ##STR1## wherein: R.sub.1 is hydrogen, alkyl, aryl, arylalkyl or ##STR2## wherein R.sub.5 is alkyl or aryl; R.sub.2 is hydrogen, alkyl, or haloalkyl;R.sub.3 is furanyl, thienyl or pyridyl;R.sub.4 is hydrogen, alkyl or arylalkyl; andn is 0, 1 or 2.Type: GrantFiled: October 25, 1979Date of Patent: March 3, 1981Assignee: E. R. Squibb & Sons, Inc.Inventor: George C. Rovnyak
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Patent number: 4244873Abstract: Process for preparing omega-hydroxy fatty acids of the formulaROCH.sub.2 (CH.sub.2).sub.n CH.sub.2 CH.sub.2 CH.sub.2 COOHwhereinR is H or acyl, and n is an integer of 0 to 18,by a very simple operation without a trouble of pollution, which comprises catalytically reacting an omega-hydroxy (or acyloxy)-alkyl-.gamma.-butyrolactone of the formula ##STR1## wherein R and n are as defined above, in the presence of a hydrogenolysis catalyst.Compounds of formula (2) are novel, and a process for preparing them is also provided.Type: GrantFiled: April 18, 1978Date of Patent: January 13, 1981Assignee: Soda Koryo Kabushiki KaishaInventors: Kiyonori Suzuki, Takeaki Eto, Takeyasu Otsuka, Shozo Abe, Sadao Yoshikawa
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Patent number: 4232011Abstract: Compounds of the formula I ##STR1## wherein R.sub.1 and R.sub.2 are each methyl or chlorine, R.sub.3 is hydrogen or C.sub.1 -C.sub.4 -alkyl, R.sub.4 is methyl or ethyl, R.sub.5 is methoxy, ethoxy, C.sub.1 -C.sub.4 -alkylthio or phenyl and X is oxygen or sulphur have valuable pesticidal in particular acaricidal properties.Type: GrantFiled: October 22, 1979Date of Patent: November 4, 1980Assignee: Ciba-Geigy CorporationInventors: Manfred Boger, Jozef Drabek, Gunter Mattern, Walter Traber
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Patent number: 4216333Abstract: A process for preparing N-tritylimidazole compounds of the formula: ##STR1## by the reaction between a tritylcarbinol derivative of the formula: ##STR2## and an imidazole derivative of the formula: ##STR3## , characterized in that the reaction is effected in the presence of a phosphorus compound of the formula: ##STR4##Type: GrantFiled: January 30, 1979Date of Patent: August 5, 1980Assignee: Sumitomo Chemical Company, LimitedInventors: Hideo Agui, Ikutaro Saji, Mitsuo Nakashita
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Patent number: 4167566Abstract: The invention relates to compounds of the formula ##STR1## in which R and R' are identical or different and may be a hydrogen, an alkyl, a dialkylamino, an alkoxy, a halogen, or a hydroxy. These compounds are useful as drugs in the control of thromboses.Type: GrantFiled: March 9, 1978Date of Patent: September 11, 1979Assignee: Pierre Fabre, S.A.Inventors: Guy Pitet, Henri Cousse, Gilbert Mouzin, Andre Delhon
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Patent number: 4153799Abstract: Compounds are presented of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, amino, halogen and nitro; R.sub.2 is selected from the group consisting of hydrogen, lower alkyl, carboxylic acids, esters and primary, secondary or tertiary amides thereof, alkylhydroxy, acylhydroxy-lower alkyl, amino-lower alkyl, alkylamino-lower alkyl, acylamino-lower alkyl and carboxaldehyde; and X is hydrogen or halogen and the pharmaceutically acceptable salts thereof.Also presented are processes to produce the above compounds and intermediates thereof. These compounds exhibit pharmacological activity as anxiolytics, sedatives, muscle relaxants and anticonvulsants.Type: GrantFiled: September 14, 1978Date of Patent: May 8, 1979Assignee: Hoffmann-La Roche Inc.Inventors: Norman Gilman, Rodney I. Fryer