Abstract: Embodiments disclosed herein are directed to the treatment of wounds using negative pressure. Some embodiments disclosed herein provide for a foam pad, which may be suitable for use in abdominal wound sites, and which may be sized in a dimensionally-independent manner. Additional embodiments provide for a wound contact layer, as well as a system for the treatment of abdominal wounds.

Abstract: Embodiments of secure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, the apparatus includes a pressure source, a user interface, and a locking mechanism. The locking mechanism can be in one of at least two states, the at least two states including a first state in which the locking mechanism physically prevents user adjustment of one or more operational parameters with the user interface and a second state in which the locking mechanism does not physically prevent user adjustment of the one or more operational parameters with the user interface. The locking mechanism can include an authentication key and a receiver configured to receive an authentication input, which may be compared to the authentication key. Providing a sufficiently matching authentication input can transition the locking mechanism from the first state to the second state, permitting adjustments to the one or more operational parameters.

Abstract: A wearable article includes a front and back elastic belts, a crotch region, a waist opening, and leg openings. Each elastic belt is a laminate having an inner sheet, an outer sheet, and an elastic member. Elastic adhesive bonding continuously bonds the elastic member for at least about 10 mm in the direction of stretch adjacent the side edges of the belts. A discrete patterned adhesive bonding is applied to at least one of the inner and outer sheets to intermittently bond the inner and outer sheets. The discrete patterned adhesive bonding extends substantially along the transverse direction between the elastic adhesive bonding, and substantially along the longitudinal direction between the distal and proximal edges of the elastic belts. The same adhesive agent provides the elastic adhesive and discrete patterned adhesive bonding. Heat bonds form side seams, and the remainder of the laminate is free of heat bonds.

Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.

Abstract: An absorbent article includes a topsheet, a backsheet, and an absorbent core disposed between the topsheet and backsheet; and a fastening system. The fastening system has a fastening component disposed on an article component. A plurality of layers overlap at least a portion of the fastening component in an overlapping region. The fastening component includes a first plurality of fastening elements integrally formed from a first set of layers and a second plurality of fastening elements integrally formed from a second set of layers.

Abstract: An evaporative bridge dressing that may be used with negative-pressure treatment of tissue. The evaporative bridge dressing may have one or more fluid transfer layers comprised of high-density wicking material enclosed between layers of film having high moisture-vapor transfer rates to reduce liquid storage and minimize pressure drop.

Abstract: In some non-limiting examples, a system for stimulating tissue growth at a tissue site may include a porous foam and a moisture barrier. The porous foam may include an exterior-facing surface, a tissue contact surface, and a plurality of struts positioned at the tissue contact surface. The plurality of struts may be configured to contact the tissue site and to create tissue deformation at the tissue site without the application of a reduced pressure. The moisture barrier may be configured to cover the exterior-facing surface of the porous foam and to trap moisture at the tissue site. Also provided are other systems, apparatus, and methods suitable for stimulating tissue growth.

Abstract: A wound dressing according to certain embodiments includes an adhesive layer for adhering the wound dressing adjacent to a wound, a wound contact layer for contacting the wound, a backing layer comprising a port, a tube having a first end connected with the port and an opposite second end, a first fitting connected to the second end of the tube, the first fitting configured for connection with a second fitting of the negative pressure wound therapy system to apply a negative pressure via the port, and a filter disposed within the first fitting. In certain embodiments, the filter is formed of polyethersulfone (PESU) and has an average pore size of at least 2 microns.

Abstract: The present invention is directed to wall box for hemodialysis interface having two isolated zones. The first zone is a clean interface zone having sources of purified water and dialysis fluids. The second zone is a waste interface zone comprising waste connectors and a waste drain.

Abstract: A dressing for treating a tissue site with negative pressure may comprise a first polymer film having a plurality of fluid restrictions, and a second polymer film comprising a plurality of standoffs disposed adjacent to the first polymer film. The first polymer film and the second polymer film may be substantially transparent to allow observation of the tissue site. In some embodiments, at least some of the standoffs may be offset from the fluid restrictions. The second polymer film may comprise fluid passages adjacent to the standoffs in some examples.

Abstract: A wound dressing includes a hydrophilic foam layer, a drape layer, superabsorbent projections, and printed indicators. The hydrophilic foam layer is configured to engage a wound bed and has a first side and a second side, the second side configured to face the wound bed. The drape layer has a first side and a second side, the second side configured to face the first side of the hydrophilic foam layer. The plurality of non-contiguous superabsorbent projections are fixed to and extend from the first side of the hydrophilic foam layer towards the second side of the drape layer. The one or more non-contiguous printed indicators surround one or more of the plurality of superabsorbent projections.

Abstract: The invention provides an apparatus for the generation and administration of a micro-nanobubble solution to a tissue, a method for the treatment of a tissue with a solution of micro-nanobubbles, and a kit for the treatment of tissue with micro-nanobubbles.

Abstract: A dopamine or drug/therapeutics delivery and monitoring system for treatment of brain disease having an implantable titrator connected to the brain, a microtube for delivery of dopamine, a second microtube for withdrawal of CSF, a micropump for controlled pumping of dopamine into the brain responsive to sensed dopamine levels in the withdrawn CSF and a mixing chamber in the implantable titrator to combine withdrawn CSF with dopamine from a reservoir in the titrator to form a mixture for controlled delivery of the mixture. The system may have a fiber optic implanted and dopamine sensor responsive to certain sensed wavelengths of light received by a microcontroller. The system further has a dopamine reservoir and a carbon fiber resistance probe and may use fast scan cyclic voltammetry. A needle memory alloy having a straight and curved phase can be deployed into a blood vessel of a vascular system for trans-vascular delivery.

Abstract: In some embodiments, a wound monitoring and/or therapy apparatus can include a wound dressing configured to be positioned over a wound. The wound dressing can support one or more sensors. The one or more sensors can include an optical sensor array cluster, which can include an optical sensor and single light source. In some embodiments, the wound dressing can include a substantially stretchable wound contact layer that includes a wound facing side and a non-wound facing side opposite the wound facing side, the wound facing side configured to be positioned in contact with a wound. The non-wound facing side of the wound contact layer can support a plurality of electronic components and a plurality of electronic connections that connect at least some of the plurality of the electronic components. The electronic components can include one or more sensors configured to obtain measurements of the wound or the periwound, or both.

Abstract: Urine collection bags, kits including urine collection bags, methods of collecting urine, and methods of manufacturing urine collection bags are disclosed herein. A urine collection bag includes an outer profile, an inner profile, and first and second external layers. The first and second external layers are sealed around a first periphery to define the inner profile. The inner profile has a container portion and an elongated portion.

Abstract: Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In one embodiment, a negative pressure source can provide negative pressure via a fluid flow path to a wound dressing comprising a stabilizing structure. The stabilizing structure can be inserted into a wound and collapse upon application of negative pressure to the wound when the stabilizing structure is positioned in the wound. A controller can in turn determine a measure of collapse of the stabilizing structure from a pressure in the fluid flow path while the negative pressure source maintains a magnitude of the pressure in the fluid flow path within a negative pressure range. The controller can output an indication responsive to the measure of collapse.

Abstract: A catheterization system including a catheter, drainage bag and one or more indicators configured to measure an attribute relating to the usage of the catheter system and communicate information about the attribute to a network, such as an EMR database. The indicators may include a location indicator, a duration indicator, an elevation indicator, a tamper indicator, a dependent loop indicator, a floor contact indicator, and a patient securement indicator. The system may autonomously detect and record one or more attributes relating to the usage of the catheter system.

Abstract: In some examples, a dressing filler for treating a tissue site may include a plurality of filler elements and a tissue interface layer. Each of the filler elements may include a first surface and a second surface opposite the first surface and separated from the first surface by a thickness. The tissue interface layer may include a first side configured to be positioned facing the tissue site and a second side positioned opposite the first side. The first surface of each of the filler elements may be coupled to the second side of the tissue interface layer. Also provided are other apparatuses, dressings, systems, and methods suitable for treating a tissue site.

Abstract: A dressing that includes a contact layer having walls defining a plurality of holes and a retainer layer comprising portions protruding into holes of a contact layer is provided herein. Systems, methods and kits using the dressing for debriding a tissue site are also provided herein.

Abstract: Dressings, systems, and methods for treating a tissue site with negative pressure are described. The dressing includes a manifold having a first surface and a second surface opposite the first surface, a first layer adjacent to the first surface, and a second layer adjacent to the second surface. The first layer and the second layer each are formed from a polymer film. A plurality of fluid restrictions are formed in the polymer film adjacent to at least the first surface. A first plurality of bonds is formed between the first layer and the second layer. The first plurality of bonds define separable sections of the manifold. A second plurality of bonds is formed between the first layer and the second layer. The second plurality of bonds define a plurality of openings.