Patents Examined by Nickey Chan
  • Steroid derivatives and their use in radioimmunoassays
    Patent number: 4221725
    Abstract: Radiolabeled steroid derivatives having the formula ##STR1## wherein St is des-hydroxy steroid moiety of (i) a hydroxy steroid intended for radioimmunoassay or (ii) a hydroxy containing derivative of a steroid intended for radioimmunoassay, said derivative having a strong affinity for the antibodies of the steroid intended for radioimmunoassay; R is hydrogen or alkyl of 1 to 3 carbon atoms; n is 0, 1, 2, 3 or 4 and the asterisk (*) indicates tagging with a radioisotope, are useful as tracers in radioimmunoassays.
    Type: Grant
    Filed: January 17, 1979
    Date of Patent: September 9, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Jack Bernstein, Ravi K. Varma, B. Richard Vogt, Frank L. Weisenborn