Abstract: Method of eliciting in a mammalian host a protective immune response to Helicobacter infection and treatment of Helicobacter infection by administering to the host an immunogenically effective amount of a Helicobacter urease or urease subunits as antigen. Vaccine compositions are also provided.
Type:
Grant
Filed:
February 23, 1994
Date of Patent:
September 18, 2001
Assignee:
OraVax, Inc.
Inventors:
Pierre Michetti, Iréne Corthésy-Theulaz, André Blum, Catherine Davin, Rainier Haas, Jean-Pierre Kraehenbuhl, Emilia Saraga