Abstract: A method, system, and computer readable medium for synchronizing performance monitors in the multiprocessor system are disclosed. The system includes a lead processor and at least one slave processor. The method includes informing the slave processor that a synchronization signal is forthcoming and waiting for an acknowledgment indicating that the slave processor is ready to receive the synchronization signal. In response to the slave processor's acknowledgment, the method includes sending the synchronization signal to the slave processor. The lead processor's performance monitors are set when the synchronization signal is sent and the slave processor's performance monitors are sent when the synchronization signal is received by the slave processor. In one embodiment, informing the slave processor that a synchronization signal is forthcoming is achieved by issuing a first inter-processor interrupt.