Patents Examined by Olga V Tcherkasskaya
  • Capsules containing high doses of levodopa for pulmonary use
    Patent number: 9393210
    Abstract: The present invention provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L. The invention further provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L wherein the capsule material comprises hydroxypropylmethylcellulose (HPMC) and titanium dioxide.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: July 19, 2016
    Assignee: Civitas Therapeutics, Inc.
    Inventors: Kevin D. Kee, Ernest D. Penachio, Abhijit Kamerkar, Michael M. Lipp, Richard P. Batycky
  • Pharmaceutical formulation containing gelling agent
    Patent number: 9387174
    Abstract: Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: July 12, 2016
    Assignees: Purdue Pharma L.P., The P.F. Laboratories, Inc., Purdue Pharmaceuticals L.P.
    Inventors: Curtis Wright, Benjamin Oshlack, Christopher Breder
  • Meal intended for human consumption
    Patent number: 9386792
    Abstract: This invention relates to a plurality of compositions for dietary health management and its use in the prevention or treatment of cardiovascular disease or type 2 diabetes, and also in the prevention and/or management of obesity and generally in weight management and loss. Thus a meal intended for human consumption is provided, the meal comprising: (a) 250-650 kilocalories (1045-4180 kiloJoules); (b) 10-50, preferably 20-50, more preferably 30-50 g fiber; (c) 10-50, preferably 10-30, more preferably 10-20 g protein; (d) 0 to 5, preferably less than 3 g starch; and (e) 0 to 2, preferably 0 to 1, most preferably 0 to 0.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: July 12, 2016
    Assignee: Conopco, Inc.
    Inventors: Mark John Berry, Heather Frances Jennifer Bligh, Mark Ian Fowler, Karl John Hunter, Katrina Macaulay
  • Pharmaceutical formulation containing gelling agent
    Patent number: 9387173
    Abstract: Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: July 12, 2016
    Assignees: Purdue Pharma L.P., The P.F. Laboratories, Inc., Purdue Pharmaceuticals L.P.
    Inventors: Curtis Wright, Benjamin Oshlack, Christopher Breder
  • Microcup compositions
    Patent number: 9388307
    Abstract: The present invention is directed to a composition for preparing the microcups and the toughness of the display panel formed from such a composition may be significantly improved. In some cases, the panel may have an elongation at break of more than 10% and it can be completely peeled off from the substrate layer on which it is formed, without causing any damage to the panel.
    Type: Grant
    Filed: November 27, 2012
    Date of Patent: July 12, 2016
    Assignee: E INK CALIFORNIA, LLC
    Inventors: Yu Li, HongMei Zang
  • Nanoparticles comprising esters of poly (methyl vinyl ether-co-maleic anhydride) and uses thereof
    Patent number: 9351940
    Abstract: The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, said nanoparticles being based on half (C1-C4) alkyl esters of poly (methyl vinyl ether-co-maleic anhydride) (PVM/MA) copolymers. Said nanoparticles can encapsulate or incorporate a product of interest for use in the agricultural, cosmetic, food or pharmaceutical fields.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: May 31, 2016
    Assignee: BIONANOPLUS, S.L.
    Inventors: Hesham H. A. Salman, Izaskun Goñi Azcarate
  • Deodorant with improved endurance and stability
    Patent number: 9302127
    Abstract: The present invention provides an improved deodorant formulation having good efficacy and excellent stability. The deodorant formulation comprises propanediol combined with zinc ricinoleate, grapefruit seed extract, and sodium bicarbonate as the principal deodorizing actives. The combination of these deodorizing active ingredients results in a formulation with strong efficacy which lasts at least 24 hours. The deodorant formulation also displays improved stability when formed into a solid stick product. These features combined provide for an improved deodorant formulation having excellent features of efficacy and stability.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: April 5, 2016
    Assignee: KNOWLTON DEVELOPMENT CORPORATION INC.
    Inventor: Hany Abo-El-Magd Mobarak
  • Low surfactant iodine topical disinfectant
    Patent number: 9302007
    Abstract: Iodine-containing germicidal compositions are disclosed that remain physically stable for extended storage periods with little to no iodine complexing agent being present. The compositions employ a mixture of emollients, such as glycerin and ethoxylanolin, to create a composition that in certain embodiments presents a cloudy or emulsion-like appearance.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: April 5, 2016
    Assignee: DELAVAL HOLDING AB
    Inventor: Mark Henderson
  • Nitric oxide generation, dilution, and topical application apparatus and method
    Patent number: 9302238
    Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: April 5, 2016
    Assignee: SYK TECHNOLOGIES, LLC
    Inventors: J. W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
  • Continuous flow production of gelatin nanoparticles
    Patent number: 9289499
    Abstract: A continuous process for the preparation of gelatin based nanoparticles in a reactor having a process channel having a mixing element therein, the process having the following steps: A) feeding separately an aqueous gelatin solution at a first rate and a water-miscible organic solvent at a second rate to the process channel of the reactor to be mixed therein, to form a suspension of non-crosslinked gelatin based nanoparticles and B) crosslinking the non-crosslinked gelatin based nanoparticles, wherein the sum of the first rate and the second rate is chosen such that the reactor has a mixing efficiency as determined by the Villermaux/Dushman method of between 0.1 and 1.5 and the period from the time point at which the aqueous gelatin solution is fed to the reactor to the time point at which the mixture of the aqueous gelatin solution and the organic solvent contacts the mixing element is at most 15 seconds.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: March 22, 2016
    Assignee: FUTURECHEMISTRY HOLDING B.V.
    Inventors: Sebastiaan Antonius Martinus Waltherus Van Den Broek, Pieter Jos Nieuwland, Kaspar Koch
  • Method for increasing the solubility of nevirapine
    Patent number: 9273049
    Abstract: The invention provides a method for increasing the solubility of nevirapine, including the steps of rendering nevirapine in a gaseous phase; and rendering the gaseous phase in a relatively more soluble solid particulate form. The invention further provides for a crystalline Form-VI (36) of nevirapine having an X-ray diffraction pattern of (2-theta values in degrees) 9.2953, 11.2023, 12.7019, 12.9796, 13.5273, 15.4670, 17.2597, 19.1038, 19.7267, 21.1303, 22.9381, 25.5589, 26.4913, 27.2150, 27.7283, 29.7134, and 33.8343 degrees two theta. The invention further provides for the preparation of microspherical and/or nanospherical Form-V (34) and crystalline Form-VI (36) of nevirapine as well as novel dosage forms including parenteral-, inhalant-, transdermal- and oral dosage forms.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: March 1, 2016
    Assignee: North-West University
    Inventors: Wilna Liebenberg, Nicole Stieger
  • Compositions comprising hydrophobically modified malodor control polymers
    Patent number: 9248209
    Abstract: Compositions comprising hydrophobically modified malodor control polymers and methods thereof are provided. In some embodiments, the composition comprises a malodor control polymer, a malodor counteractant comprising a perfume, an aqueous carrier, and a ph of about 6 to about 8. Such compositions may be used to reduce or neutralize malodors on surfaces or in the air.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: February 2, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Ricky Ah-Man Woo, Cahit Eylem, Yonas Gizaw, Larissa Azirbayeva, Zaiyou Liu, Jeffrey Scott Dupont
  • Implantable intraocular drug delivery apparatus, system and method
    Patent number: 9241829
    Abstract: The present invention relates to an apparatus, system and method for, and for providing, intraocular delivery of an active agent. The apparatus, system and method may include an implantable scaffold and an active agent associated with the implantable scaffold. The implantable scaffold and the active agent may be configured to be completely contained within the eye upon implantation. The implantable scaffold may be a mechanical scaffold, or the implantable scaffold may be a chemical scaffold.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: January 26, 2016
    Assignee: Abbott Medical Optics Inc.
    Inventors: Brooke C. Basinger, Daniel J. Urbaniak
  • Method of making an anhydrous, pigmented composition
    Patent number: 9168211
    Abstract: The invention relates to a method of making an anhydrous, pigmented sunscreen composition. The method comprises first adding a hydrophobic silica to a lipid phase comprising a dispersed color pigment and an organic UV-filter and homogenizing the mixture. Next, a hydrophilic silica is added and re-homogenization is performed.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: October 27, 2015
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Luna Fascina, Danielle Lima Lorenzetti, Maria Emilia de Oliveira Brenha Ribeiro, Rodrigo Collina Romanhole
  • Use, as antidandruff agent, of (ethoxyhydroxyphenyl) alkyl ketone or ethoxyhydroxyalkylphenol compounds
    Patent number: 9161893
    Abstract: The present invention relates to the use, as an antidandruff agent, of a compound of formula: in which: R1 represents a hydrogen atom or a hydrocarbon-based radical; R? represents a C1-C18 hydrocarbon-based radical, optionally substituted with a hydroxyl group; C—X represents C?O or CH—OH.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: October 20, 2015
    Assignee: L'OREAL
    Inventor: Maria Dalko
  • Multilayer films for delivery of flavor
    Patent number: 9161890
    Abstract: An oral care composition having enhanced flavor release comprising an orally acceptable carrier containing a first flavor and a multilayer film for extended or delayed flavor release, the multilayer film including at least a center layer containing a second flavor, the center layer positioned between two outer surface layers, each surface layer including a release modulating agent, the first and second flavor being the same or different. The film is adapted to adhere to an oral cavity surface and the outer surface layers may comprise a mucoadhesive polymer, e.g. carboxy polymethylene, polycarbophil or polyvinyl pyrrolidone, and a film forming polymer, eg. hydroxypropylmethyl cellulose (HPMC). Suitable release modulating agents include HPMC and polyvinyl acetate. The carrier may be a toothpaste or mouthwash.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: October 20, 2015
    Assignee: Colgate-Palmolive Company
    Inventors: Thomas Boyd, Ben Gu, Leonora Leigh
  • Coating for objects, in particular in public facilities and/or means of transportation, for preventing the transmission of infections
    Patent number: 9127189
    Abstract: The invention relates to a covering (1) for objects, in particular in public facilities and/or means of transportation, for preventing the transmission of infections, the covering being made of covering material, in particular having a virucidal and/or virostatic and/or bactericidal and/or bacteriostatic and/or fungicidal and/or fungistatic effect, wherein the covering material is intended to be applied externally to surfaces (2) of objects. According to the invention, the covering material is flexible and can be adapted to the outer shape of the object.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: September 8, 2015
    Assignee: Blucher Gmbh
    Inventor: Hasso von Blücher
  • Dry powder fibrin sealant
    Patent number: 9119897
    Abstract: A fibrin sealant comprises a mixture of first microparticles that comprise fibrinogen, second microparticles that comprise thrombin, and additive material. The additive material may be particulate, and may be, for instance, a biocompatible, water-absorbent, material, a biocompatible, water-swellable material, a biocompatible, water-insoluble material, a polysaccharide or silica.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: September 1, 2015
    Assignee: PROFIBRIX B.V.
    Inventors: Glen Patrick Martyn, Jacob Koopman
  • Compositions and methods for treating traumatic brain injury
    Patent number: 9101580
    Abstract: The disclosure provides compositions treating traumatic brain injuries such as concussions. In one embodiment, the composition comprises phosphatidylserine, phosphatidylcholine, quercetin, astaxanthin, R-alpha lipoic acid, N-acetyl cysteine, taurine, L-glutamine, carnitine, D-ribose, creatine, epigallocatechin gallate, melatonin, ginkgo leaf extract, curcumin and L-glycine. The disclosure also provides methods for treating traumatic brain injuries such as concussions by administering an effective amount of the compositions described within.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: August 11, 2015
    Inventors: Matthew Bennett, Gus Peller
  • Method and apparatus for the enhancement of the biocidal efficacy of monoalkyldithiocarbamate salts
    Patent number: 9078436
    Abstract: The present invention provides a method of treating an aqueous system for biocide control, by adding an acidified solution that includes monoalkyldithiocarbamate salt and alkyl isothiocyanate to an aqueous system. A biocide feed system is also provided that is configured to generate a reproducible level of alkyl isothiocyanate. The method and system provide effective levels of alkyl isothiocyanate for rapid biocidal activity, along with levels of monoalkyldithiocarbamate salt which can decompose to form additional alkyl isothiocyanate and provide longer-term biocidal activity.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: July 14, 2015
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Thomas E. McNeel, Richard A. Clark, William C. Ganus, Richard D. Lusk, Jr., Graciela H. Vunk, Luis A. Zugno