Patents Examined by Oyeleye Alexander Alabi
  • Patent number: 12151239
    Abstract: The present invention provides methods and devices for simple, low power, automated processing of biological samples through multiple sample preparation and assay steps. The methods and devices described facilitate the point-of-care implementation of complex diagnostic assays in equipment-free, non-laboratory settings.
    Type: Grant
    Filed: May 18, 2022
    Date of Patent: November 26, 2024
    Assignee: NOVEL MICRODEVICES, INC.
    Inventors: Andrea Maria Dominic Pais, Rohan Joseph Alexander Pais
  • Patent number: 12151954
    Abstract: This automated analyzer comprises a first system 11 that does not need to use degassed water, a second system 12 for which it is preferable to use degassed water and that comprises a degassing device 21 for producing degassed water and a second pump 19 for delivering the degassed water, and a tank 1 having formed therein a first compartment 4 for storing water to supply to the first system 11 and a second compartment 5 for storing degassed water to supply to the second system 12. The second system 12 comprises a circulation system, which comprises a suction flow path 20 and return flow path 24 for connecting the degassing device 21, the second pump 19, and the second compartment 5 of the tank 1, and a usage system, which comprises a discharge flow path 22 and connection flow path 27 for connecting the degassing device 21 and a usage unit for using the degassed water.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: November 26, 2024
    Assignee: Hitachi High-Tech Corporation
    Inventors: Akihiro Shimase, Kazumi Kusano
  • Patent number: 12145156
    Abstract: A configurable device arrangement for performing at least one unit operation in a biopharmaceutical process includes a base rack and a plurality of holders for releasable direct or indirect attachment of process components, in particular single-use process components, for the unit operation. The holders are in turn adapted to be releasably attached directly or indirectly to the base rack. The device arrangement further includes a positioning system which defines specific positions for the holders relative to the base rack.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: November 19, 2024
    Assignee: SARTORIUS STEDIM BIOTECH GMBH
    Inventors: Stefan Weisshaar, Mario Deuse, Martin Leuthold, Thomas Krumbein
  • Patent number: 12135292
    Abstract: A method for detecting an analyte in a sample is disclosed. The method includes providing a mobile device having a camera and an illumination source. A test strip having a test field with at least one test chemical for performing an optical detection reaction in the presence of the analyte is provided. The sample is applied to the test field. Several images of a region of the test strip are captured. The region includes at least part of the test field to which sample is applied. The images are captured before and after the sample is applied and with the illumination source turned on and off. The images captured are compared and differences in light intensities are determined. Analyte concentration is determined using the images captured and the determined light intensities.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: November 5, 2024
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Max Berg, Daniel Sieffert, Volker Tuerck, Simon Wetzel, Momme Winkelnkemper
  • Patent number: 12109519
    Abstract: Disclosed herein is a molecular imprinted protective face mask comprising a supportive structure, a surface material that receives and retains a molecular imprint and that is positioned to contact airborne molecules during use, a molecular imprint of a bioactive molecule wherein an imprinted cavity is at least one of a bioactive molecule with a molecular configuration that captures a specific airborne and/or microdroplet-borne molecule and a protein with a binding site that captures a specific molecule.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: October 8, 2024
    Assignee: Utah Valley University
    Inventor: Timothy Edwin Doyle
  • Patent number: 12102998
    Abstract: In one example in accordance with the present disclosure, a cell sorting device is described. The cell sorting device includes a microfluidic channel to serially transport individual cells from a volume of cells along a flow path. A sensor disposed in the microfluidic channel distinguishes between a cell to be analyzed and waste fluid. The cell sorting device includes at least two fluid transport devices disposed within the microfluidic channel. The at least two fluid transport devices include a cell ejector to, responsive to detection of a cell to be analyzed, eject the cell to be analyzed from the cell sorting device and a waste transport device to direct the waste fluid to a waste reservoir.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: October 1, 2024
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Viktor Shkolnikov
  • Patent number: 12102999
    Abstract: A device for handling a particle suspension, in particular a cell suspension, which includes at least one channel for flowing the particle suspension, a pumping unit configured to move a driving fluid and control element for controlling the pumping unit. Also, a method for handling a particle suspension, which includes flowing the particle suspension in or out of at least one channel using a driving fluid for driving the particle suspension in the channel.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: October 1, 2024
    Assignee: ASTRAVEUS
    Inventors: Jérémie Laurent, Vincent Thisse
  • Patent number: 12099060
    Abstract: The present invention relates to a nanovesicle comprising a heterodimeric G-protein coupled receptor, a method for preparing the nanovesicle, a field effect transistor-based taste sensor comprising the nanovesicle, and a method for manufacturing the taste sensor. The field effect transistor based taste sensor functionalized by the nanovesicle comprising the heterodimer G-protein coupled receptor according to the present invention has excellent sensitivity and selectivity and may highly specifically detect a sweet taste substance in real time, by using the heterodimeric G-protein coupled receptor and the nanovesicle comprising the same.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: September 24, 2024
    Assignee: Seoul National University R&DB Foundation
    Inventors: Tai Hyun Park, Seung Hun Hong, Hyun Seok Song, Hye Jun Jin, Sae Ryun Ahn
  • Patent number: 12097499
    Abstract: An embodiment of a system includes a compartment-generating device, a compartment detector, and electronic computing circuitry. The device is configured to generate compartments of a digital assay, at least one of the compartments having a respective volume that is different from a respective volume of each of at least another one of the compartments. The detector is configured to determine a number of the compartments each having a respective number of a target that is greater than a threshold number of the target. And the electronic circuitry is configured to determine a bulk concentration of the target in a source of the sample in response to the determined number of compartments. Because such a system can be configured to estimate a bulk concentration of a target in a source from a polydisperse digital assay, the system can be portable, and lower-cost and faster, than conventional systems.
    Type: Grant
    Filed: January 6, 2023
    Date of Patent: September 24, 2024
    Inventors: Toan Huynh, Bernhard Hans Weigl, Samantha A. Byrnes, Kevin Paul Flood Nichols
  • Patent number: 12092641
    Abstract: Disclosed are methods and kits for analyzing a sample comprising 1,5-anhydroglucitol and a possible first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte. Also provided are kits including reagents for practicing the claimed methods.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: September 17, 2024
    Inventors: Richard C. Willson, Victoria M. Hlavinka, Binh V. Vu, Federico Augusto Ruiz-Ruiz, Marco Antonio Rito Palomares, Mary A. Crum
  • Patent number: 12085562
    Abstract: The present invention relates to a biochemical assay apparatus in which a sample processing device is controlled by a detection instrument through a series of linear and rotary actuations to execute a biochemical assay on a biological fluid sample.
    Type: Grant
    Filed: November 11, 2019
    Date of Patent: September 10, 2024
    Assignee: Great North Research and Innovation Ltd
    Inventors: Georgios Gerardos, Dan Haworth, Paul Scott, Will Harris, Leigh Shelford
  • Patent number: 12076722
    Abstract: A fluidic coupler to engage a plurality of flow cells of a sensor device includes a body and a plurality of fluidics interfaces formed in the body. Each fluidic interface of the plurality of fluidics interfaces includes an opening, a first port in fluid communication with the opening, a second port, and a third port in fluidic communication with the second port.
    Type: Grant
    Filed: February 9, 2023
    Date of Patent: September 3, 2024
    Assignee: Life Technologies Corporation
    Inventors: Jon Hoshizaki, Patrick Leung, David Marran, Mark Reed
  • Patent number: 12077560
    Abstract: The present disclosure provides devices, systems, kits and methods useful for quantitation of biomolecules such as intact proteins and nucleic acids.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: September 3, 2024
    Assignee: Waters Technologies Corporation
    Inventors: Jennifer M. Nguyen, Matthew A. Lauber, Yun Wang Alelyunas, Gregory T. Roman, Henry Y. Shion
  • Patent number: 12071611
    Abstract: Disclosed are a rare cell capture system and an application thereof. The system comprises a fluid tube device, a circulation power apparatus device, a component capture device and an optional anticoagulant release device, the circulation power apparatus device and the component capture device being connected in series to a fluid circulation system via the fluid tube device to form an extracorporeal fluid circulation pathway, the component capture device comprising a microfluidic chip or a chipset. Also disclosed is a method for using the capture system to capture rare cells in blood. The system and the application thereof have the advantages of being large-capacity, in-line and low-hemolysis.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: August 27, 2024
    Assignees: Chengdu Precisome Biotechnology Co., Ltd.
    Inventors: Hubing Shi, Yanchu Li, Qi Xu, Xiangju Kong, Xueyan Wang, Hewen Han
  • Patent number: 12066440
    Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: August 20, 2024
    Assignee: Labrador Diagnostics LLC
    Inventors: Chinmay Pangarkar, Karan Mohan, James R. Wasson
  • Patent number: 12061150
    Abstract: The invention generally relates to detecting biological substances. In certain aspects, the invention is directed to a method directing one or more wavelengths of light within a deep ultraviolet (UV) spectrum into a medium to excite a biological substance in the medium, detect emission from the excited biological substance via a plurality of semiconductor photodetectors, and analyze the deep UV emission data for presence of a deep UV spectral signature indicative of the biological substance, wherein presence of the deep UV spectral signature indicates that the medium comprises a biological substance. The invention is also directed to identifying a pathogen in a medium comprising a pathogen and a non-pathogen biological substance.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: August 13, 2024
    Assignee: ORB XYZ, INC.
    Inventors: Lorenzo Falzarano, Andreia Michelle Smith-Moritz
  • Patent number: 12053755
    Abstract: A gas analysis system and method with a spectrometer, such as a Fourier transform infrared spectrometer, utilizing a reactor, such as a catalytic reactor, for providing reference spectra.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: August 6, 2024
    Assignee: MLS ACQ, INC.
    Inventor: Martin L. Spartz
  • Patent number: 12054766
    Abstract: The present disclosure provides a device that includes a base comprising a substrate having a first major surface, a pressure sensitive adhesive adhered to at least a portion of the first major surface, a polymeric cover film coupled to the substrate via the adhesive, a plurality of isolated closed compartments disposed between the substrate and the cover film, and an aqueous liquid disposed in two or more of the closed compartments. The cover film is a composite film comprising ethylene vinyl acetate copolymer, a linear copolymer of ethylene and a higher alkene, and a tackifier. Each compartment of the plurality is defined by a seal that prevents liquid communication with at least one other compartment of the plurality. Methods of using the device for partitioning a sample, for analyzing a sample, and for culturing a microorganism are also provided.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: August 6, 2024
    Assignee: NEOGEN FOOD SAFETY US HOLDCO CORPORATION
    Inventors: Evan D. Brutinel, Kurt J. Halverson
  • Patent number: 12053781
    Abstract: Disclosed herein are solvent reservoir systems for steady flow delivery and simultaneous monitoring of solvent level and solvent density within the solvent reservoir systems and methods for monitoring the solvent reservoir systems and providing feedback to a user or adjusting the systems in response to the monitored characteristics.
    Type: Grant
    Filed: September 1, 2023
    Date of Patent: August 6, 2024
    Assignee: Waters Technologies Corporation
    Inventor: Sean Eric Anderson
  • Patent number: 12050211
    Abstract: The present invention relates to a device and a method for evaluating performance of a deodorant using a superabsorbent polymer (SAP), and the device and method are capable of quantitatively evaluating deodorant performance by collecting ammonia adsorbed to deodorant materials including the SAP and measuring the amount of ammonia thereof.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: July 30, 2024
    Assignee: LG Chem, Ltd.
    Inventors: Jihyang Son, Min Hwan Jung, Jin Woo Lee