Patents Examined by Oyeleye Alexander Alabi
  • Patent number: 11513096
    Abstract: The present disclosure provides an analysis chip device used in capillary electrophoresis.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: November 29, 2022
    Assignee: ARKRAY, INC.
    Inventor: Naotsugu Onuma
  • Patent number: 11513116
    Abstract: The present disclosure relates to a cleaning device and a chemiluminescence detector. A cleaning device is provided with a cup inlet station and a cup outlet station, wherein the cleaning device comprises a pedestal, a plurality of magnetic adsorption components, a turntable arranged on the pedestal, and a primary cleaning mechanism arranged on the pedestal, wherein each of the plurality of magnetic adsorption components comprises a plurality of magnets; magnetic adsorption heights of a plurality of magnets of the first magnetic adsorption component are equal and are recorded as A; magnetic adsorption heights of a plurality of magnets of the middle magnetic adsorption component are equal and are recorded as B, and B>A.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: November 29, 2022
    Assignee: Shenzhen New Industries Biomedical Engineering Co., Ltd.
    Inventors: Liang Zhu, Li Yin, Yi Hu, Dingping Ban, Wanguan Yi, Shuai Tong
  • Patent number: 11511276
    Abstract: A liquid handling device includes a common channel, a plurality of wells, a magnetic beads chamber and a plurality of valves. The plurality of valves are rotary membrane valves disposed on the circumference of a first circle. The magnetic beads chamber is disposed on a circumference of the second circle concentric with the first circle.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: November 29, 2022
    Assignee: Enplas Corporation
    Inventor: Nobuya Sunaga
  • Patent number: 11498067
    Abstract: An apparatus for patterning biological cells, and a method of patterning and coculturing biological cells using the apparatus. The apparatus includes a fluidic structure having an outlet and a plurality of inlets, the fluidic structure is arranged to facilitate a flow of a plurality of different cells in a cell suspension therethrough, wherein each of the plurality of inlets is arranged to facilitate a loading of the plurality of different cells from a plurality of supplies into the fluidic structure; and a flow controlling device arranged to control the flow of the plurality of different cells through the fluidic structure and/or the loading of the plurality of different cells from the plurality of supplies through the plurality of inlets; wherein the fluidic structure is further arranged to facilitate a simultaneous observation of the plurality of different cells arranged in a predetermined pattern in the fluidic structure.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: November 15, 2022
    Assignee: City University of Hong Kong
    Inventors: Dong Sun, Lei Fan, Tao Luo
  • Patent number: 11484882
    Abstract: The microfluidic device has a first reservoir that preferably includes a first liquid. The first liquid is being held by a capillary stop valve in the first reservoir. A second reservoir is in fluid communication with the first reservoir. The second reservoir has a second liquid and a sample support disposed therein. The second reservoir has an inlet opening defined therein. A draining unit is adjacent to the second reservoir. The draining unit is in fluid communication with the second reservoir. The draining unit has a first absorption member disposed therein.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: November 1, 2022
    Assignee: Intelligent Virus Imaging Inc.
    Inventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
  • Patent number: 11485945
    Abstract: The method is for preparing a sample in a microfluidic device. A microfluidic device is provided that has a first reservoir in fluid communication with a second reservoir in fluid communication with and adjacent to a draining unit that has a first absorbing member disposed therein. The first reservoir contains a first liquid that is held in the first reservoir by a capillary stop valve connecting the first and second reservoirs. The second reservoir has a sample support disposed therein. A second liquid, containing substances, is added to the second reservoir. The second liquid contacts the first liquid and the first absorbing member. The first absorbing member absorbs the second liquid and the first liquid. The substances adhere to the sample support.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: November 1, 2022
    Assignee: Intelligent Virus Imaging Inc
    Inventors: Janosch Hauser, Gustaf Kylberg, Göran Stemme, Ida-Maria Sintorn, Niclas Roxhed
  • Patent number: 11486888
    Abstract: An improved sample conveyer for articulating a sample across the flat platen of a spectrum analyzer relative to a scan window in the platen. The conveyor includes a sample truck configured for movement across the surface of the platen, the sample truck having a scan aperture. A spur gear is rotatably mounted about the aperture, and a drive gear is engaged to the spur gear. The drive gear has a plurality of magnets embedded therein, and a second plurality of magnets is affixed to the sample truck. A translation mechanism resides beneath the platen which includes a sled mounted on parallel rails for linear translation there along, and a motor mounted on the sled. Magnets on both the sled and drive gear index and engage corresponding magnets on the sample truck to implement complex orbital, hypotrochoid or epitrochoid scan patterns for more accurate particulate analysis.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: November 1, 2022
    Inventors: Robert R. Wilt, Lou Faustini
  • Patent number: 11484884
    Abstract: A biological sample collection system can include a sample collection vessel having a sample collection chamber with an opening configured to receive a biological sample into the sample collection chamber. The biological sample collection system can additionally include a selectively movable sleeve valve configured to associate with the opening of the sample collection chamber. The biological sample collection system can additionally include a sealing cap that is configured to associate with the selectively movable sleeve valve and with the sample collection vessel. The sealing cap can include a reagent chamber having reagent(s) stored therein, and when the sealing cap is associated with the sample collection vessel, the selectively movable sleeve valve opens, dispensing the reagent(s) into the sample collection chamber.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: November 1, 2022
    Assignee: Ancestry.com DNA, LLC
    Inventors: Kevin Gregg Williams, Jeremy Johnson, Bryce Twede, Michael Andersen, Michael S. Horito, Collin Sorensen
  • Patent number: 11480556
    Abstract: Disclosed is a real-time method for detecting copper and silver in water in parts per billion. Total silver is detected by adding a 2% nitric acid solution to the sample; after ten minutes, adding a buffer solution comprising water, sodium bicarbonate, sodium carbonate and EDTA to the sample; adding an indicator comprising Cadion 2B, EtOH, and Triton X-100 to the sample; after one minute, reading the absorbance of the sample using a spectrophotometer with a target peak of 515 nm; and determining the silver concentration by comparing the absorbance of the sample to the absorbances of known silver standards.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: October 25, 2022
    Assignee: HF Scientific, LLC
    Inventors: Dorian Cauceglia, Nicholas J. Pusateri
  • Patent number: 11479804
    Abstract: Methods of detecting the presence of toxins in a sample using electrophoretic separations and of performing electrophoretic separation of complex samples are provided. The method of detecting the presence of toxins includes reacting a sample and a substrate with a signaling enzyme which converts the substrate to the product in a reaction medium, introducing a run buffer into a separation channel having an inlet end, selectively introducing at least one of the substrate and the product of the reaction medium into the inlet end of the separation channel, electrophoretically separating the substrate and the product, and determining the rate of conversion of the substrate to the product, wherein a change in the rate of conversion is indicative of the presence of toxins.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: October 25, 2022
    Assignee: Applied Research Associates, Inc.
    Inventors: Alyssa Catharyn Henry, David Judson Ross
  • Patent number: 11474096
    Abstract: A breath alcohol measurement device has a sample collector (1) with a sample inlet (2) configured for a contactless introduction of a breath sample. A measurement unit (9) has a sensor (16) that generates a measurement signal based on an alcohol content in the breath sample. A control and evaluation unit (4) determines the alcohol content based on the measurement signal and transmits a result-specific signal to an output unit (5). Some of the breath sample provided into the sample inlet (2) is applied, at least intermittently via a main flow duct (10), to the sensor (16) via a measurement gas duct (21) that is connected via an outlet to the environment (7). Between the sample inlet (2) and the outlet of the main flow duct there is a further outflow opening (6) through which some of the breath sample introduced into the sample inlet exits into the environment.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: October 18, 2022
    Assignee: Dräger Safety AG & Co. KGaA
    Inventors: Jens Rekow, Stefan Morley, Stefan Barten, Carsten Stemich, Michael Richenberger, Sebastian Schröter
  • Patent number: 11467154
    Abstract: An optical nano-biosensing system and a method thereof are provided. The optical nano-biosensing system includes a nano-plasmonic sensing device, a high-resolution analog-to-digital converter, a signal acquisition and processing device, and an intelligent electronic device. The nano-plasmonic sensing device further includes a light-source control circuit, a sample receiver, a light detector, and a signal-amplifying circuit. The sample receiver receives a sample. The light-source control circuit generates an incident light from a light source to be projected onto the sample receiver. The light detector detects an emergent light from the sample receiver to generate a detection signal. The signal-amplifying circuit converts the detection signal to generate an amplified signal. The high-resolution analog-to-digital converter digitizes the amplified signal to generate a digital signal.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: October 11, 2022
    Assignee: National Chung Cheng University
    Inventors: Sung-Nien Yu, Tsung-Heng Tsai, Lai-Kwan Chau
  • Patent number: 11465148
    Abstract: Certain embodiments are directed to finite step emulsification device and/or methods that combine finite step emulsification with gradients of confinement for the formation of a 2D monolayer array of droplets with low size dispersion.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: October 11, 2022
    Assignee: PATTERN BIOSCIENCE, INC.
    Inventor: Ross Johnson
  • Patent number: 11458467
    Abstract: A microfluidic probe head is provided. The microfluidic probe head comprises a processing surface. The processing surface has a first and second aperture and a fluid injection channel, which leads to the first aperture. The microfluidic probe head comprises also a first fluid aspiration channel which leads to the second aperture. Thereby, the second aperture forms a slot in the processing surface. Furthermore, a microfluidic probe may be provided comprising the microfluidic probe head.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: October 4, 2022
    Assignee: Bio-Rad Laboratories Inc.
    Inventors: Robert Dean Lovchik, Anna Fomitcheva Khartchenko, Govind Kaigala, Iago Pereiro Pereiro
  • Patent number: 11453002
    Abstract: The present disclosure provides a microfluidic device configured to deliver a controlled amount of a liquid to an analysis tool, wherein the microfluidic device comprises: a buffer tank configured to contain a liquid and/or a gas; at leas one level sensor configured to measure a liquid level in the buffer tank; a pneumatic system configured to create selectively a positive or a negative pressure in the buffer tank; at least one intake port to let in a liquid in the buffer tank; at least one delivery port to inject a controlled amount of liquid from the buffer tank onto the analysis tool; at least one drain port with a controlled drain valve, located on the lower part of the buffer tank to discharge the liquid from the buffer tank; a first check valve located upstream of the intake port and a second check valve between the buffer tank and the analysis tool.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: September 27, 2022
    Assignee: WITHINGS
    Inventors: Ianis Oueslati, Charlotte Leger, Marine Kirat
  • Patent number: 11442050
    Abstract: Provided is an aluminum ion detector. The aluminum ion detector may include apple extracts having a predetermined concentration, and metal nano particles coupled to the apple extracts.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: September 13, 2022
    Assignee: Korea University Research and Business Foundation, Sejong Campus
    Inventors: Jin Sung Park, Gyu Do Lee, Woong Kim, Hyun Jun Park
  • Patent number: 11442064
    Abstract: The present invention includes a novel method and system for identification of microorganisms in samples that proteins and other biological material from non-microorganism sources (e.g., proteins of mammalian origin) that can interfere with identification of the microorganisms. The methods and systems described herein include use of a single-use chromatography medium to purify intact proteins prior to mass spectrometry analysis. The chromatography medium and the methods described herein can rapidly and efficiently remove of a substantial portion of interfering biological material (e.g., mammalian proteins) from a crude cell lysate while preserving high signal strength and removing enough of the interfering protein(s) to allow for identification of the microorganism(s) by mass spectrometry analysis.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: September 13, 2022
    Assignee: Thermo Fisher Scientific OY
    Inventors: Mikko Koskinen, Leena Valmu, Joni Rannisto, Kelly Flook, Roger Grist, Anssi Rantakari
  • Patent number: 11442049
    Abstract: A method using ascorbic acid (Vitamin C) as part of a chemical test kit employing sodium rhodizonate as the coloring agent for producing a yellow-orange to purple color transition for detection of lead in various media eliminating the use of strong acid.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: September 13, 2022
    Inventors: Frederic G Dewalt, David C Cox
  • Patent number: 11433395
    Abstract: Provided is a separating apparatus including separating unit configured to apply external force to a fluid sample containing two or more components immiscible with each other and having different specific gravities to separate the fluid sample into separation target and non-separation target, and a transfer mechanism configured to apply a pressure to the separation target separated by the separating unit to transfer the separation target.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: September 6, 2022
    Assignee: UNIVERSITY OF YAMANASHI
    Inventor: Yoshiaki Ukita
  • Patent number: 11433394
    Abstract: A flow control device comprises a laminate structure of an electroactive material layer and a non-actuatable layer. An array of orifices is formed in one of the layers wherein the orifices are open in one of the rest state and actuated state and the orifices are closed in the other of the rest state and actuated state. Actuation of the electroactive material layer causes orifices to open and close so that flow control function may be implemented.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: September 6, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Eduard Gerard Marie Pelssers, Herbert Lifka, Roland Alexander Van De Molengraaf, Daan Anton Van Den Ende, Franciscus Johannes Gerardus Hakkens, Mark Thomas Johnson, Cornelis Petrus Hendriks, Anja Van De Stolpe