Patents Examined by Oyeleye Alexander Alabi
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Patent number: 11353470Abstract: The present invention discloses a spectral-potentiometric-thermometric multi-dimensional titration analysis instrument, which comprises a spectral titration measurement device, a thermometric titration measurement device and a potentiometric titration measurement device which are arranged in parallel, meets the simultaneous measurement requirements of different analysis methods in chemical analysis, improves the measurement precision of different measurement methods, and effectively reduces the workload of separate experiments. The present invention further provides a usage method of the analysis instrument, provides analysis results of different angles and different characterization parameters for the change process of the material structure in the chemical reaction by conducting comparison analysis on data obtained using different measurement techniques, and effectively reduces the workload of titration analysis.Type: GrantFiled: December 23, 2019Date of Patent: June 7, 2022Inventor: Fei Wang
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Patent number: 11344883Abstract: A microfluidic device and a method of detecting the presence of an analyte in a fluid. In one embodiment, the microfluidic device includes: (1) a substrate, (2) a waveguide supported by the substrate and configured to receive light and (3) a microfluidic channel contacting the waveguide and configured to convey a fluid, a characteristic of the light changing under influence of an analyte in the fluid.Type: GrantFiled: August 26, 2019Date of Patent: May 31, 2022Assignee: MAX-IR LABS INCORPORATEDInventor: Ecatherina Roodenko
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Patent number: 11338289Abstract: Microfluidic device comprising a tank (6) supplying a microchannel (2) with a first fluid (S), and a circuit (8) in which a flow of a second fluid can be established without contact with the microchannel (2). The circuit (8) passes through the tank (6) or is connected to the tank (6) by a pipe (30). The circuit (8) comprises a first on/off valve (12) mounted in parallel with a first proportional valve (11), these first valves (11, 12) being controllable so as to modify the pressure applied in the tank (6) to the first fluid (S) by the second fluid.Type: GrantFiled: March 29, 2018Date of Patent: May 24, 2022Assignee: FLUIGENTInventors: Clémence Vergne, Benjamin Rouffet, Lionel Matthys, Robert Breton, Nicolas Petit
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Patent number: 11333658Abstract: A method of detecting a urine test strip from a photographed image of the urine test strip is disclosed. The disclosed method of detecting a urine test strip includes: receiving input of a urine test strip image, which is a photographed image of a urine test strip including a first and a second marker; detecting a first and a second marker image within the urine test strip image; detecting an area between the first and second marker images within the urine test strip image; and detecting a reagent pad and a colorimetric table in the urine test strip image by matching an area of interest, which represents a position of the reagent pad and the colorimetric table in the urine test strip image, with the area between the first and second marker images.Type: GrantFiled: January 2, 2018Date of Patent: May 17, 2022Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITYInventors: Whoi-Yul Kim, Jong Woo Lim, Min Su Kim
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Patent number: 11333610Abstract: The invention provides a percarboxylic acid concentration-determining device capable of determining the concentration of percarboxylic acid contained in an aqueous solution for chemical sterilization or disinfection that contains a percarboxylic acid as an active ingredient; and an indicator solution for use in preparing the device. The indicator solution contains a starch, an iodide, a thiosulfate, a water-soluble organic solvent, and water, with the starch, the iodide, the thiosulfate, and the water-soluble organic solvent being present in the following proportions, based on the total amount taken as 100 mass %: (a) starch: 0.01 to 5 mass %; (b) iodide: 0.01 to 5 mass %; (c) thiosulfate: 0.01 to 10 mass %; and (d) water-soluble organic solvent: 0.1 to 40 mass %, wherein the total amount of (a), (b), and (c) is greater than 0.6 mass %.Type: GrantFiled: February 14, 2018Date of Patent: May 17, 2022Assignee: SARAYA CO., LTD.Inventors: Madan Mali, Satomi Sakai, Emiko Kawamukai
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Patent number: 11331660Abstract: A digital dispense system for preparing and analyzing a plurality of samples. The system includes two or more fluid droplet ejection devices. Each fluid droplet ejection device contains a fluid droplet ejection cartridge containing at least one fluid to be dispensed. The fluid droplet ejection cartridge is attached to a translation mechanism for moving the fluid droplet ejection cartridge back and forth over a sample holder in an x direction. A sample tray translation mechanism is provided for moving a sample tray along a production path in a y direction orthogonal to the x direction through the two or more fluid droplet ejection devices.Type: GrantFiled: May 20, 2019Date of Patent: May 17, 2022Inventors: Bruce A. Deboard, John Glenn Edelen, Michael A. Marra, III, Sam Norasak
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Patent number: 11333645Abstract: An embodiment provides A method for measuring fluoride concentration in an aqueous solution, including: preparing a metal-ligand complex, wherein the metal-ligand complex comprises chromeazurol S and aluminum; placing the metal-ligand complex in a sample containing fluoride, wherein the placing generates a color change by releasing the chromeazurol S from the metal-ligand complex; and measuring, using colorimetric techniques, a concentration of fluoride within the sample, wherein the measuring comprises measuring an absorbance wavelength of a colorimetric ligand. Other embodiments are described and claimed.Type: GrantFiled: April 17, 2019Date of Patent: May 17, 2022Assignee: HACH COMPANYInventor: Angella Nicholle Greenawalt
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Patent number: 11331669Abstract: An apparatus may include a first microfluidic valve coupled between a first reservoir and a fluid channel. The first microfluidic valve may include a fluid agitator to break a meniscus formed at an air-fluid interface and release fluid from the first reservoir into the fluid channel in response to an electrical signal. The apparatus may also include a second microfluidic valve coupled between a second reservoir and the fluid channel. Fluid from the first reservoir and fluid from the second reservoir mix in the fluid channel.Type: GrantFiled: February 15, 2017Date of Patent: May 17, 2022Assignee: Hewlett-Packard Development Company, L.P.Inventors: Pavel Kornilovich, Alexander Govyadinov, Nick McGuinness
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Patent number: 11318466Abstract: One example includes a device that may include a heating element and a molecular binding site. The heating element may heat a fluid volume, interfaced with the heating element, in response to a voltage being applied to the heating element, the heat transforming the fluid volume from a liquid state into a vaporized state to generate fluid motion within the fluid volume. The molecular binding site may be disposed proximate to the heating element, in which a portion of the fluid volume expands when the fluid volume transforms from the liquid state into the vaporized state, the vaporized state of the fluid volume generating the fluid motion within a target fluid that is disposed within the molecular binding site.Type: GrantFiled: July 19, 2017Date of Patent: May 3, 2022Assignee: Hewlett-Packard Development Company, L.P.Inventors: David P. Markel, Erik D Torniainen, Alexander Govyadinov, Pavel Kornilovich
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Patent number: 11318458Abstract: A cassette may include a substrate and a die coupled to the substrate wherein the substrate is made of modified polyetherimide (PEI). A system for ejecting a fluid into an assay may include at least one dispense head, the at least one dispense head including a substrate and a die coupled to the substrate wherein the substrate is made of modified polyetherimide (PEI).Type: GrantFiled: April 3, 2017Date of Patent: May 3, 2022Assignee: Hewlett-Packard Development Company, L.P.Inventors: Gary G. Lutnesky, Paul Schweitzer, Michael W. Cumbie
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Patent number: 11320344Abstract: An aseptic sampling flow path kit to be applied to an isolator having a liquid delivery port includes a sampling section, a first flow path that communicates with the sampling section, and that connects an inside of the isolator to an outside of the isolator through the liquid delivery port, and at least one one-way valve which is disposed in the first flow path, and that limits flow of fluid in the first flow path to a direction from the sampling section toward the liquid delivery port. In the kit, at least a part of the first flow path is a germicidal flow path to which a germicidal unit is applicable.Type: GrantFiled: January 2, 2019Date of Patent: May 3, 2022Assignees: NIHON KOHDEN CORPORATION, OSAKA UNIVERSITYInventors: Hodaka Makino, Hirotsugu Kubo, Masahiro Kinooka
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Patent number: 11320383Abstract: The present invention relates to a method for the determination of the film forming amines on surfaces by the detection of a colored complex. The invention also relates to the use of the absorber material for the detection of the film forming amines. The invention also relates to a kit of parts comprising the components capable of the determination of film forming amines.Type: GrantFiled: March 12, 2018Date of Patent: May 3, 2022Assignee: KURITA WATER INDUSTRIES LTD.Inventors: Julia Jasper, Kirstin Zimmer, Andre De Bache, Wolfgang Hater
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Patent number: 11311872Abstract: The invention relates to a pipetting device having tube with an opening at one end for suctioning or discharging a sample fluid, and can be operatively connected to a pressure generation device at the other end. A first electrode is formed on the pipetting device that forms a measuring capacitor together with a second electrode formed by at least one part of the sample fluid and that can be received in the tube and the measuring capacitor is operatively connected to a measuring unit, and the measuring unit is designed to determine a volume of the suctioned or discharged sample fluid according to the capacity of the measuring capacitor. The invention also relates to a fluid processing system having a pipetting device of this type, as well as a method for determining a processed fluid volume during pipetting with a pipetting device of this type.Type: GrantFiled: July 19, 2017Date of Patent: April 26, 2022Assignee: TECAN TRADING AGInventor: Philipp Ott
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Patent number: 11311879Abstract: There is provided a microfluidic device for reversing a flow through a microfluidic channel. The microfluidic device comprises a first microfluidic channel extending between a first inlet and a first outlet, a second microfluidic channel which fluidically connects a first point of the first microfluidic channel to a second outlet via a first valve, a third microfluidic channel which fluidically connects a second point of the first microfluidic channel to a second inlet via a second valve, the second point being located between the first point and the first outlet, and at least one circuit for opening the first valve and the second valve. The first and the second valves are arranged to be initially closed, Upon opening of the first and the second valve during use, the flow direction through the first microfluidic channel between the first point and the second point is reversed.Type: GrantFiled: February 5, 2019Date of Patent: April 26, 2022Assignee: miDiagnostics NVInventor: Benjamin Jones
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Patent number: 11311884Abstract: A biological sample collection system can include a sample collection vessel having a sample collection chamber with an opening configured to receive a biological sample into the sample collection chamber. The biological sample collection system can additionally include a selectively movable sleeve valve configured to associate with the opening of the sample collection chamber. The biological sample collection system can additionally include a sealing cap that is configured to associate with the selectively movable sleeve valve and with the sample collection vessel. The sealing cap can include a reagent chamber having reagent(s) stored therein, and when the sealing cap is associated with the sample collection vessel, the selectively movable sleeve valve opens, dispensing the reagent(s) into the sample collection chamber.Type: GrantFiled: November 21, 2018Date of Patent: April 26, 2022Assignee: Ancestry.com DNA, LLCInventors: Kevin Gregg Williams, Jeremy Johnson, Bryce Twede, Michael Andersen, Michael S. Horito, Collin Sorensen
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Patent number: 11311880Abstract: A microchip controlling system comprises a microchip which is configured by adhesion of an elastic sheet and a plate/sheet member, and on which a flow path is provided as an inadhesive section between the elastic sheet and the plate/sheet member; and a microchip controlling apparatus comprising a valve mechanism which is inflated or deflated so as to control the flow path to be opened or closed.Type: GrantFiled: March 27, 2018Date of Patent: April 26, 2022Assignee: NEC CORPORATIONInventor: Yasuo Iimura
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Patent number: 11311876Abstract: An analysis chip for determining an efficient anticancer drug or anticancer drug combination for cancer cells, according to an embodiment of the present disclosure, includes a chamber which is a unit for analyzing single cancer cells, and a plurality of valves configured to regulate a fluid to be injected into the chamber, wherein the chamber includes a channel through which a fluid including an anticancer drug and a cell lysis buffer flows, a cell sorting part configured to focus cancer cells flowing along the channel, a cell capturing part configured to focus the cancer cells focused by the cell storing sorting part, and an antibody array configured to capture proteins secreted from the captured cancer cells and intracellular protein through cell lysis.Type: GrantFiled: July 10, 2018Date of Patent: April 26, 2022Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Sung Yang, Jong Chan Choi
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Patent number: 11305284Abstract: An embodiment of a system includes a compartment-generating device, a compartment detector, and electronic computing circuitry. The device is configured to generate compartments of a digital assay, at least one of the compartments having a respective volume that is different from a respective volume of each of at least another one of the compartments. The detector is configured to determine a number of the compartments each having a respective number of a target that is greater than a threshold number of the target. And the electronic circuitry is configured to determine a bulk concentration of the target in a source of the sample in response to the determined number of compartments. Because such a system can be configured to estimate a bulk concentration of a target in a source from a polydisperse digital assay, the system can be portable, and lower-cost and faster, than conventional systems.Type: GrantFiled: November 26, 2018Date of Patent: April 19, 2022Assignee: Tokitae, LLCInventors: Toan Huynh, Bernhard Hans Weigl, Samantha A. Byrnes, Kevin Paul Flood Nichols
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Patent number: 11291988Abstract: The invention concerns pipette tips for connecting to a pipette tube of a pipetting device are used for taking up and discharging fluids. The pipette tip is in the shape of an elongated tube forming a pipette body that has an opening at one end and is designed for connecting to the pipette tube at the other end. The pipette tip has a first electrode as a volume measuring electrode of a measuring capacitor and a second electrode as an immersion detector electrode. The first electrode is located on an outer surface of the pipette body or is embedded in the pipette body, and the second electrode is located at least partially on an inner surface of the pipette body.Type: GrantFiled: July 21, 2017Date of Patent: April 5, 2022Assignee: TECAN TRADING AGInventors: Philipp Ott, Matthias Dzung, Martin Kuster
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Patent number: 11285481Abstract: A fluid flow controller for introducing fluids into a microfluidic device is provided. The fluid flow controller comprising, at least one high resistance fluid pathway provided between an inlet port and a connection port; at least one low resistance fluid pathway between the inlet and connection port; and at least one valve configured to enable fluid flow through the high resistance fluid pathway, the low resistance fluid pathway or both.Type: GrantFiled: September 1, 2017Date of Patent: March 29, 2022Assignee: Fluidic Analytics LimitedInventors: Anthony Douglas, Tuomas Pertti Jonathan Knowles, Thomas Mueller, Andrew Lynn