Abstract: The invention provides a nucleotide sequence representing a pathogenicity island found in species of pathogenic mycobacteria. The islands are shown as SEQ ID NOs: 3 and 4 and comprises several open reading frames encoding polypeptides. These polypeptides and their use in diagnosis and therapy form a further aspect of the invention.
Type:
Grant
Filed:
September 16, 1998
Date of Patent:
December 5, 2000
Assignee:
St. George's Hospital Medical School
Inventors:
John Hermon-Taylor, Tim Doran, Douglas Millar, Mark Tizard, Mark Loughlin, Nazira Sumar, John Ford