Abstract: An adhesive composition includes compounds having the following formula: wherein R1 is alkyl, alkoxy alkyl, anhydride, ether, ester, or amide, and R2 and R3 are hydrogen, alkyl, alkoxy alkyl, hydroxy, alkenyl, ester, carboxylic acid or ether and wherein R1 is optionally omitted where R2 and R3 are not both hydrogen.

Abstract: A method for coating keratinous substances including applying an agent for coating keratinous substances comprising:(1) an aqueous/organic solution containing:(a) at least one non-crosslinked polymer capable of forming a deposit or a film on a keratinous substrate after drying and exhibiting a critical temperature Tc for solubility in water of the LCST or UCST type ranging from 0.degree. to 100.degree. C.; and(b) at least one total organic solvent for the polymer within the temperature range for use of the composition which is partially or completely miscible with water and more volatile than water; or(2) an aqueous solution or aqueous dispersion containing:(a) at least one non-crosslinked polymer capable of forming a deposit or a film on a keratinous substrate after drying and exhibiting a critical temperature Tc for solubility in water of the LCST or UCST type ranging from 0.degree. to 100.degree. C.

Abstract: An oral lubricant having particular usefulness for alleviating the symptoms of xerostomia based on a beta-glucan polymer in an orally acceptable carrier or vehicle.

Abstract: A method of making a dosage device is provided including the steps: admixing at least one active ingredient which is a pesticide in solid form at 25.degree. C., is sparingly soluble in water, and has an average particle size of less than 5 microns, with a disintegrating agent, to provide a compressible mix; and compressing the compressible mix into a unitary dosage device capable of disintegrating in water to form a suspension of the active ingredient of a particle size less than about 5 microns in the water.

Abstract: The present invention relates to hydrophilic, highly swellable hydrogels which are coated with nonreactive, water-insoluble waxes in a quantity of from about 0.05 to about 2% by weight, based on uncoated hydrogel.

Abstract: A stable composition for topical application is provided which contains at least one enzyme, at least one polyol, the latter being present in a quantity which is effective for obtaining a water activity value of the composition of less than or equal to 0.85, and at least one structuring agent chosen from polymers and oils, for the purpose of stabilizing the enzyme. In such a composition, the enzyme retains its efficacy over time. The composition obtained can be used for cleansing and/or caring for and/or protecting the skin and/or keratinous fibers.

Abstract: Novel methods are provided for treating hypertension in humans which comprise administering therapeutic amounts of pharmaceutically-acceptable non-halide salts of potassium. Preferred salts are potassium bicarbonate and potassium phosphate. The methods may also be used to lower the blood pressure of normotensive individuals. Dietary supplementation is a preferred and convenient method of administration.

Abstract: A stable non-aqueous carrier for personal care compositions comprising:a) about 80-98% by weight of a non-ionic liquid triblock EO/PO/EO copolymer of MW=1000-5000;b) about 2-20% by weight of a non-ionic solid triblock EO/PO/EO copolymer of MW=4000-16,000.

Abstract: A controlled release, oral, solid, pharmaceutical composition for a reduced daily dosage regimen is described where the therapeutic ingredient is a poorly soluble basic drug. The formulation comprises the use of a water-soluble alginate salt, a complex salt of alginic acid and an organic carboxylic acid in admixture with the therapeutic drug. A particular embodiment comprising a once a day dosage form for clarithromycin is also described.

Abstract: An improved soft contact lens material, existing as a hydrogel, is formed by a polymer containing a fluorinated monomer, a hydroxyalkyl ester of acrylic or methacrylic acid, and an N-vinyl lactam. The polymer may also contain other hydrophilic and/or hard hydrophobic monomers, crosslinking agents, and uv-absorbing agents. Contact lenses made of these combinations have high water of hydrations, are highly wettable, have extremely high oxygen permeabilities and are resistant to protein deposits and other forms of attached debris.

Abstract: A method is provide for controlling the proliferation of molluscs in target habitat by applying to the habitat a compound or mixture of compounds which are fatty acid amides, disubstituted fatty amides, fatty acid alkanolamides and ethoxylated or propoxylated derivatives of amides, alkyl and aryl polyethoxylated or polypropoxylated primary and secondary alcohols, block copolymers of ethylene oxide and propylene oxide, fatty acid substituted alkyl-aminocarboxylic acids, substituted amido and aminosulfates and aminosulfonates, alkylphenoxy polyethoxy ethanols, and ethoxylated tallow diamines. The above compounds are generally classified as surfactants, penetrants, wetting agents, detergents or emulsifiers having either nonionic or amphoteric properties. The performance of these compounds and their mixtures are further defined by their hydrophilic to lipophilic ratio or HLB and by their solubility as defined by their cloud point temperature.

Abstract: A pharmaceutical ointment is disclosed containing to 10 percent by mass of micronized piroxicam, 15 to 30 percent by mass of hydrophobic carrier(s), 60 to 75 percent by mass of water, 0.1 to 10 percent by mass of additive(s), and 2 to 5 percent by mass of emulsifiers selected from (i) a poly(ethylene glycol) alkyl or alkenyl ether and (ii) a sorbitane ester of a fatty acid or an oleic acid in a mass ratio of 3:1 to 1:3. The ointment is free from skin irritative action and has local antiphlogistic activity. In addition, a process for preparing he pharmaceutical ointment is provided.

Abstract: A pharmaceutical composition for the controlled release of medicinal drugs, which has the property of adhering to biologic tissues is described. The characteristic features of the composition are a plurality of small-size units capable of ensuring a gradual release of the active ingredient they contain the units being coated with a bioadhesive polymer layer. The composition makes it possible to keep the release controlling function separate from the function providing bioadhesion and can be adapted inter alia to oral, ocular, rectal, vaginal, nasal or periodontal administrations. An advantageous process for making the composition is also disclosed.

Abstract: The cosmetic composition of this invention which is a 2-methacryloyloxyethylphosphorylcholine polymer (Poly MPC) in a preferable amount of 0.001% to 10% by weight based on the total weight of the cosmetic composition. The cosmetic composition can repair damage to the skin and hair, such as dryness, loss of luster, etc. and enhance the moisture preservation capability thereof. It also has a good feel when applied.

Abstract: A racetrack surface composition including a synthetic polymer component, a hydrocarbon oil fluid between 25.degree.-90.degree. F., and a particulate material such as sand. The synthetic polymer component is preferably either an elastomer, or an elastomer in combination with non-elastomeric polymer; or generally a mixture of oil soluble and oil dispersible polymer which together with the oil form a binder for the particulates. The racetrack composition readily forms a pad and the cushion portion does not clump or compact but maintains its granular, rakeable quality even at track temperatures above about 130.degree. F. The composition is not adversely affected by wet weather. The invention further includes the addition of carbon black to the racetrack composition in order to improve weatherability. In the event that the racetrack composition is not readily rakeable, the invention teaches the post addition of a rakeability promoter to improve rakeability.

Abstract: A bile acid sequestrant having a crosslinked polymeric matrix and having branches supported on the polymeric matrix and providing bonding sites for binding bile acid conjugates to the sequestrant, pharmaceutical compositions containing the sequestrant for treatment of elevated plasma cholesterol level are described.

Abstract: A pharmaceutical oral controlled release composition comprising a multiplicity of microgranules or pellets, each of said pellets consisting of a core of active ingredient and binder and of a membrane applied upon said core, is described, wherein the active ingredient is a bile acid and the pellets have a particle-size of from 400 to 2000 microns.

Abstract: A topical ointment for the treatment of epidermal traumas such as burns, wounds, rashes lesions, and decubital ulcers (bed sores). The ointment includes a mixture of polymyxin, bacitracin, neomycin, iodine and sugar. The preferred polymyxin is polymyxin B sulfate, the bacitracin is bacitracin zinc, the neomycin is neomycin sulfate, the iodine is povidone-iodine, and table sugar.

Abstract: In accordance with the present invention, an ion-exchange composition has been formed which comprises synthetic resin support particles, dispersant capable of suspending the support particles in an aqueous medium to inhibit or prevent agglomeration, and fine synthetic resin layering particles. In a preferred embodiment, the complex can be formed by contacting a suitable dispersant with monomer in an aqueous solution in which the monomer is insoluble. Under suitable conditions for suspension polymerization, the monomer will polymerize to form resin support particles having dispersant irreversibly attached to those particles. The dispersant is irreversibly attached to the synthetic resin support particles, either by covalent bonding or permanent physical entanglement. The dispersant is also attached to the fine layering particles, either by covalent bonding or electrostatic forces. The result is formation of a support particle-dispersant-layering particle complex.

Abstract: A method for improving the antibacterial efficacy of an ophthalmic solution, particularly a solution for the care of contact lenses, comprises providing an article molded from a plastic resin including an inorganic carrier retaining antibacterial metal ions, and placing the ophthalmic solution in contact with the plastic resin.