Patents Examined by P. Rhodes
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Patent number: 5223419Abstract: A transacting DNA binding factor is disclosed. The ASF 1 protein factor specifically binds to the sequence motif TGACG found upstream of the promoter in many plant genes. Coexpression of this protein factor augments the level of expression of the up-regulated promoter containing the TGACG motif.Type: GrantFiled: February 1, 1991Date of Patent: June 29, 1993Assignee: The Rockefeller UniversityInventors: Fumiaki Katagiri, Eric Lam, Nam-Hai Chua
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Patent number: 5196525Abstract: Novel transcription initiation regions that provide for enhanced transcription of a DNA sequence, particularly a plant sequence, are provided.Type: GrantFiled: April 8, 1991Date of Patent: March 23, 1993Assignee: University of British ColumbiaInventors: Joan C. McPherson, Robert Kay
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Patent number: 5185253Abstract: Transgenic plants are disclosed which are resistant to virus infection by Potato Virus X and Potato Virus Y. Plant genes and transformation vectors are also disclosed. Potato plants, for example, Russet Burbank variety, are made resistant to dual infection by Potato Virus X and Potato Virus Y by transforming the plant to express the coat proteins of the two viruses.Type: GrantFiled: October 31, 1990Date of Patent: February 9, 1993Assignee: Monsanto CompanyInventor: Nilgun E. Tumer
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Patent number: 5164316Abstract: Novel transcription initiation regions that provide for enhanced transcription of a DNA sequence, particularly a plant sequence, are provided.Type: GrantFiled: August 17, 1989Date of Patent: November 17, 1992Assignee: The University of British ColumbiaInventors: Joan C. McPherson, Robert Kay
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Patent number: 5157207Abstract: A method for the production of a plant of reduced stature is provided comprising the introduction of a bacterial cell into a seed or a plant, the bacterial cell being capable of replicating in the plant and of inducing a reduction in plant stature. A seed and a plant modified by introduction of such a bacterial cell are also provided.Type: GrantFiled: February 6, 1990Date of Patent: October 20, 1992Assignee: Crop Genetics InternationalInventors: Peter S. Carlson, Jed W. Fahey, Jeffrey L. Flynn
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Patent number: 5093120Abstract: The invention concerns novel isolates of Bacillus thuringiensis (B.t.) which contains a toxin(s) which is active against adult nematode worms and larvae. This B.t. toxin(s) can be used to treat animals and plants hosting susceptible nematodes.Type: GrantFiled: May 24, 1990Date of Patent: March 3, 1992Assignee: Mycogen CorporationInventors: David L. Edwards, Jewel Payne, George G. Soares
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Patent number: 5084384Abstract: A method for bacterially producing IGF-I is disclosed in which Gram-negative bacteria are caused to express a gene consisting of a lamB or ompF signal sequence operatively joined to a DNA sequence encoding IGF-I and producing IGF-I which is secreted into the periplasmic space of the bacteria.Type: GrantFiled: May 10, 1990Date of Patent: January 28, 1992Assignee: Monsanto CompanyInventors: Edith Wong, Michael L. Bittner
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Patent number: 5070018Abstract: A method of controlling expression of a DNA segment under the control of a nod gene promoter which comprises administering to a host containing a nod gene promoter an amount sufficient to control expression of the DNA segment of a compound of the formula: ##STR1## in which each R is independently H or OH, is described.Type: GrantFiled: November 7, 1986Date of Patent: December 3, 1991Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Norman K. Peters, John W. Frost, Sharon R. Long
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Patent number: 5057422Abstract: This invention relates to recombinant DNA comprising vector-DNA and a DNA sequence corresponding with, or relates to, a salicylate-inducible promoter of a GRP gene of plants, such as tobacco plants. The invention also relates to microorganisms, plant cells and plants transformed using the recombinant DNA, to a process for introducing an inducible property in plants and to a process for producing a polypeptide or protein, using plant cells and plants transformed using the recombinant DNA.Type: GrantFiled: March 22, 1989Date of Patent: October 15, 1991Assignees: Mogen International N.V., Rijksuniversiteit LeidenInventors: John F. Bol, Bernardus J. C. Cornelissen, Johannes A. L. van Kan
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Patent number: 5023179Abstract: Detection of a cellular factor from pea and tobacco which binds to a repeated pentameric motif of TGACG present in the -90 to -60 region of the CaMV 35S promoter is disclosed. Also disclosed is a 21 bp promoter element which is capable of imparting root expression capability to a rbcS-3A promoter, normally a green tissue specific promoter.Type: GrantFiled: November 14, 1988Date of Patent: June 11, 1991Inventors: Eric Lam, Philip N. Benfey, Philip M. Gilmartin, Nam-Hai Chua
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Patent number: 5013658Abstract: This invention relates to improved methods for transposon tagging as a route to plant gene isolation. The specific improvements comprise efficient means for preselecting plants which have undergone transposition. Through use of this preselection, it is possible to substantially reduce the number of plants which must be inspected to locate individuals having the transposon excised and inserted into a gene of interest. The result is a substantial savings in time, costs and efficiency associated with growing and screening large numbers of plants for tagging and isolation of a desired plant gene.Type: GrantFiled: May 13, 1988Date of Patent: May 7, 1991Assignee: DNA Plant Technology CorporationInventors: Hugo Dooner, Jonathan Jones, Pal Maliga
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Patent number: 4997930Abstract: Maize cDNA coding for nitrite reductase is cloned, using a spinach nitrite reductase cDNA as a heterologous probe, and is characterized. A method is provided to use the cloned maize nitrite reductase cDNA to determine the number of nitrite reductase genes per maize genome and to study nitrite reductase mRNA regulation in maize.Type: GrantFiled: March 16, 1989Date of Patent: March 5, 1991Assignee: Ciba-Geigy CorporationInventors: Kristine N. Lahners, Steven J. Rothstein
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Patent number: 4990607Abstract: A transacting DNA binding factor is disclosed. The ASF-1 protein factor specifically binds to the sequence motif TGACG found upstream of the promoter in many plant genes. Co-expression of this protein factor augments the level of expression of the up-regulated promoter containing the TGACG motif.Type: GrantFiled: March 14, 1989Date of Patent: February 5, 1991Assignee: The Rockefeller UniversityInventors: Fumiaki Katagiri, Eric Lam, Nam-Hai Chua
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Patent number: 4970168Abstract: Transgenic plants are disclosed which are resistant to virus infection by Potato Virus X and Potato Virus Y. Plant genes and transformation vectors are also disclosed. Potato plants, for example, Russet Burbank variety, are made resistant to dual infection by Potato Virus X and Potato Virus Y by transforming the plant to express the coat proteins of the two viruses.Type: GrantFiled: January 27, 1989Date of Patent: November 13, 1990Assignee: Monsanto CompanyInventor: Nilgun E. Tumer
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Patent number: 4963665Abstract: The invention provides DNA sequences encoding a human preproinsulin-like growth factor I protein and novel extension peptides. A novel preproinsulin-like growth factor I protein and novel extension peptides are also provided. The present invention further provides a human IGF-I gene which has been sequenced and which encodes at least two preproinsulin-like growth factor-I proteins. Various genes and DNA sequences useful in producing essentially pure mature IGF-I, preproinsulin-like growth factor I proteins and IGF-I gene related proteins are also provided.Type: GrantFiled: November 20, 1986Date of Patent: October 16, 1990Assignee: Washington UniversityInventors: Peter S. Rotwein, Gwen G. Krivi
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Patent number: 4948735Abstract: The invention concerns novel and useful mutant microbes which are capable of releasing substantial amounts of any of several periplasmic or recombinant proteins into the culture medium when carrying an expressed Kil gene. Though E. coli are exemplified, the invention is broadly applicable to the making of mutants of other microbes, for example, Salmonella, Klebsiella, and Rhizobium. A key feature of the invention is the use of a novel selection procedure employing a plasmid comprising the kil gene.Type: GrantFiled: February 6, 1987Date of Patent: August 14, 1990Assignee: Repligen CorporationInventors: Salvador E. Luria, Joan L. Suit, Jennifer A. Jackson
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Patent number: 4948734Abstract: The invention concerns novel isolates of Bacillus thuringiensis (B.t.) which contain a toxin(s) which is active against adult nematode worms and larvae. this B.t. toxin(s) can be used to treat animals and plants hosting susceptible nematodes.Type: GrantFiled: August 12, 1987Date of Patent: August 14, 1990Assignee: Mycogen CorporationInventors: David L. Edwards, Jewel Payne, George G. Soares