Patents Examined by Padmashri Ponnalori
  • Cyclic peptide inhibitors of .beta..sub.1 and .beta..sub.2 integrin-mediated adhesion
    Patent number: 5821329
    Abstract: The present invention describes cyclic peptide compounds which modulate integrin mediated adhesion. These compounds can inhibit both .beta..sub.1 and .beta..sub.2 mediated adhesion. The invention further relates to therapeutic uses for these compounds in the treatment of adhesion related pathologies.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: October 13, 1998
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Thomas J. Lobl, Shiu-Lan Chiang, Wolfgang Scholz, Nancy Delaet, Pina Cardarelli