Abstract: Process for the restoration of an osseous defect or deficiency by filling with osseous tissue with the aid of a bioreactive granular material causing an osteostimulation, the particles of said granular material being disintegrated from the inside, dissolved and replaced by osseous tissue, the granular material containing 40 to 55% SiO.sub.2, 10 to 32% Na.sub.2 O, 0 to 12% P.sub.2 O.sub.5 and 10 to 32% CaO, which has a grain size distribution between 280 and 425 .mu.m, sharp edges, an irregular profile and surface microdefects or microcracks.
Type:
Grant
Filed:
April 19, 1990
Date of Patent:
April 20, 1993
Assignee:
FBFC International S.A.
Inventors:
Evert Schepers, Paul Ducheyne, Raymond Kempeneers
Abstract: Improved hexamethylmelamine containing parenteral emulsions are prepared in the absence of organic solvents and containing low levels of biocompatible emulsifiers using ultrahigh energy Microfluidizer.RTM. processing equipment. The emulsions have oil phase droplets with average diameters of less than about 0.4 microns with size distributions of less than about +/-50%.