Abstract: A system and method for assessing breathing and vocal tract sound production of a user. The system comprises a first sensor generating a vocal tract sound signal representing vocal tract sounds produced by the user, a second sensor generating a breathing signal representing breathing movement of the user, and a signal processing unit for processing the vocal tract sound and breathing signals. The method comprises the steps of sensing vocal tract sounds produced by the user and providing a vocal tract sound signal representative thereof, sensing breathing movement of the user and providing a breathing signal representative thereof, receiving the signals via an analog input for processing the signals, generating a combined signal by superimposing the vocal tract sound and breathing signals, and displaying the combined signal to the user.

Abstract: An in situ breast tumor temperature profile measuring probe includes a rod, thermal sensors and electrical output leads. The thermal sensors are formed in spaced apart holes in an outer insulating layer of the rod and a common electrical input lead to provide an electrical input signal to the thermal sensors is disposed below and has portions exposed at the holes and electrically connected to the thermal sensors. The thermal sensors receive the electrical input signal from the common electrical input lead, sense the temperature of biological matter adjacent to the thermal sensors and produce an electrical output signal correlated thereto. Each electrical output lead mounted to the outer insulating layer is in electrical contact with a different one of the thermal sensors to receive the electrical output signal from the one thermal sensor and output the same.

Abstract: A non-invasive method and apparatus for monitoring changes in intracranial pressure which removes extracranial effects from the measurements. The method and apparatus can include the supplying of a fixed frequency electrical output to a transducer coupled to the patient's head, thereby generating an acoustical tone burst in the patient's head which generates a first echo and a second echo, the first echo reflecting from a first interface in the side of the patient's head coupled to the transducer, and the second echo reflecting from a second interface at the opposite side of the patient's head. The first and second echoes are received by the transducer which can generate a first electrical signal and a second electrical signal, wherein the first and second electrical signals vary in accordance with the corresponding first and second echoes.

Abstract: A micro-perimeter technique using a portable computer and a projector, and using two screening methods, multi-resolution static and bi-directional kinetic. The static method, as applied to a static test, starts with relatively low-resolutions, and only the unseen zones are selectively remapped under higher resolutions during successive iterations. The bi-directional kinetic method, as applied to a kinetic test, uses a response to a continuously moving target, and the unknown response delay is compensated for by an algorithm that merges the patient's response to measurements at the same visual location, but with opposite scanning directions. Offline visualization of the mapping results is performed automatically superimposed over the fundus image.

Abstract: In accordance with the present invention there is provided a surgical instrument for the removal of biological material through an opening within a patient, wherein biological material being larger than the opening within the patient. The surgical instrument includes a specimen retrieval bag having at least one wall. The specimen retrieval bag has an open end, a closed end and a longitudinal axis extending therebetween, wherein the open end is for receiving biological materials therein. The instrument further includes at least one material transfer member attached to the wall adjacent to the open end. The material transfer member extends radially from the wall and is in fluid communication with the bag.

Abstract: A personal PAP smear apparatus and method for collecting a non-intrusive cell or tissue sample for medical testing such as cervical cancer screening is provided. The apparatus includes an insertion handle, a flexible speculum ring, and a means for movably attaching the speculum ring to the insertion handle. The speculum ring includes two adjacent ring halves circumferentially divided to permit expansion of the collapsed speculum tube housed within the hollow ring halves. The method of the invention includes insertion of the flexible speculum assembly into the user's vagina, movement of the speculum ring to a raised position encircling the user's cervix, separating the ring halves to expand the tube and define the speculum bore, and inserting a sampling tool through the bore until it touches the cervix or surrounding surface areas for tissue sampling.

Abstract: The apparatus includes a single-use compartment assembly which includes a reservoir for blood and a needle element by which blood is obtained from the user. A vacuum system is actuated which draws blood through the needle element into the blood reservoir. An ultrasound signal is directed through the reservoir. There is no return ultrasound signal until there is sufficient blood in the reservoir. When the blood reaches a given level, it contacts a clotting agent present in the reservoir to begin the clotting process. The ultrasound signals are transmitted and return until clotting has been completed, as determined by a pre-established increase in the two-way propagation time relative to unclotted blood. The prothrombin time is then calculated and compared with an acceptable range.

Abstract: The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

Abstract: An apparatus for inducing sputum samples for diagnosing pulmonary disorders, especially as it relates to detection of early stages of lung cancer. The apparatus is comprised of a pneumatic chest compression vest, a pneumatic pressure generator, and a mouthpiece connected to a nebulizer. Sputum samples are induced by applying an oscillating force to the chest via the pneumatic chest compression vest and pressure generator, while simultaneously providing an aerosolized solution (such as normal or hypertonic saline) via the nebulizer while the patient is standing. The sample is subsequently evaluated to ascertain a patient's risk of or the presence of a pulmonary disorder such as lung cancer.

Abstract: A blood sampling device is provided for mounting on a patient's forearm or other suitable body location, which incorporates an admixture reservoir and a closed blood sampling cavity in a single housing, the functional elements of which are firmly mounted and easily accessible to the caregiver. The blood sampling cavity is preferably accessed by a blunt cannula, which is readily retained in the sampling cavity by virtue of the cavity's secured position and elevated location on the sampling device housing during the sampling procedure, without the need for a cannula locking device.

Abstract: Disclosed herein is an articulated guidewire for insertion into a blood vessel. The articulated guidewire includes a rotatable sensor cable, a sensor, a connector, and a satellite wire. The sensor cable has a proximal end and a distal end. A sensor connects to the sensor cable near the distal end and rotates with the sensor cable. The satellite wire attaches to the distal end of the sensor cable and holds the sensor cable in the blood vessel. The connector includes a ball and socket joint which aligns the satellite wire and the sensor cable at a variable angle.

Abstract: The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the same. The device, has proximal and distal ends and includes an elongated high strength proximal portion having proximal and distal ends. The device further includes a distal portion having proximal and distal ends. The distal end of the proximal portion and the proximal end of the distal portion are connected by a connector. The distal portion is formed of a superelastic alloy composition. Preferably, the connector is also formed of the superelastic alloy composition. The superelastic alloy composition includes, in atomic percent, from about 28 to about 52% nickel, from about 48 to about 52% titanium, and up to about 20% of at least one alloying element selected from the group consisting of palladium, chromium, and hafnium.

Abstract: An apparatus and method of identifying artifacts in signals indicative of detected myoelectrical activity is provided. The method includes providing electrodes to obtain a plurality of first signals over time. The first signals are produced from an internal organ in the abdominal cavity of a living being. The first signals include spurious signals as a result of artifact. A sensor obtains a plurality of second signals simultaneously as the first signals are obtained. The second signals are indicative of a respiratory function of the living being and include spurious signals indicative of artifact. The first and second signals are recorded simultaneously. The occurrence of artifacts is identified by noting irregularities in both the recorded first and second signals during a particular time frame.

Abstract: An endocervical sampling device 10 and method comprising a cytology brush 12 slidably received within a protective cylindrical sleeve 14 and having a tapered distal tip 16 protected by a penetrable seal 18.

Abstract: A preferred joint movement monitoring system (10) includes a carrier (18) configured for wearing by a subject about a wrist thereof and a plurality of position sensors (12, 14, 16) coupled with the carrier (18) for sensing various hand positions of the subject. The preferred carrier (18) is in the form of an elastic wrist band that encompasses the wrist and adjacent portions of the hand and forearm without covering any portions of the subject's fingers. The preferred sensors (12, 14, 16) include Hall effect sensors mounted to the carrier (18) on the forearm side of the wrist.

Abstract: A biopsy instrument and method of using such are provided wherein the biopsy instrument includes a proximal actuation handle, an elongate flexible member, and a distal assembly. The flexible member, connected to and extending from the actuation handle, includes an aspiration conduit for fluid connection with a vacuum source and for permitting the flow of fluid from the distal end to the proximal end of the biopsy instrument. The flexible member may include an irrigation conduit for supplying irrigation fluid to the distal end. The actuation handle includes a stationary member and an actuation device, and may include a sample chamber, a sample collector, valves for regulating the vacuum in the aspiration conduit and the fluid flow in the irrigation conduit, and a pressure increasing device for selectively increasing the pressure of the fluid supplied to the distal end.

Abstract: A blood viscosity measuring system and methods for measuring blood viscosity system monitors the change in height of two, oppositely-moving, columns of blood from the circulating blood of a patient and, given the dimensions of a capillary tube through which the blood flows, determines the blood viscosity over a range of shears, especially low shears. The system includes a tube set (disposable or nonisposable) that includes a pair of riser tubes, a capillary tube of predetermined dimensions that is coupled between the riser tubes (or that forms a portion of one riser tube) and a valve mechanism for controlling the circulating flow of blood from the patient into the riser tubes. Respective sensors monitor the movement of the columns of blood in each of the riser tubes and an associated microprocessor analyzes these movements, along with the predetermined dimensions of the capillary tube to determine the viscosity of the patient's circulating blood.

Abstract: A high performance coil over-core guide wire. The guide wire incorporates a nickel-titanium core with a stainless steel coil to provide a wire with improved kink resistance and good pushability.

Abstract: A cervical sampling system for collecting a cervical sample for a Pap test. The cervical sampling system includes an insertion tube and an introduction guide member that guides the insertion tube into a vaginal cavity. The vaginal insertion tube includes an insertion depth indicator to allow the user to determine the appropriate depth to insert the tube. A cervical sampler is positioned within the vaginal insertion tube and extends into the vaginal cavity to collect samples. The insertion tube and cervical sampler include signaling members which cooperate to indicate to the user when the cervical sample has been rotated through a complete revolution.

Abstract: In a process and an apparatus for the detection of the contact and/or the interaction of a catheter arranged in a patient's vessel, in particular in a patient's blood stream, with the patient's tissue, in order to contribute to an improved detection of this contact or to make it possible for the first time to permit statements during an ablation process regarding the ablation depth or regarding the interaction with the tissue, a device is provided for the detection of a voltage at at least one catheter electrode, wherein the voltage between the catheter electrode and a further electrode is measured, and wherein the further electrode is a neutral electrode in contact with the patient's body or a further electrode installed on the catheter.