Abstract: A biocompatible material for bone repair is described. The bone repair composition includes a mixture of a type I collagen, a type I collagen-glycosaminoglycan coprecipitate, tricalcium phosphate; and bioactive glass. Methods of using the composition for bone repair, and a kit for the bone repair composition are also described.

Abstract: The present invention relates to a method of producing a direct compression tablet composition comprising the step of processing ibuprofen, a hydrophilic polymer, and an inorganic excipient by an extrusion process to produce an extruded composition in which the ibuprofen forms a solid dispersion/solution within the hydrophilic polymer. The invention is particularly useful in preparing oral dissolvable tablets. Also provided are composition comprising an inorganic excipient and ibuprofen within a hydrophilic polymer.

Abstract: Described herein are therapeutic pH responsive compositions comprising a block copolymer and a therapeutic agent useful for the treatment of cancer.

Abstract: Provided are compositions, methods, and solutions for generating aqueous glucomannan solutions with hydrogen compositions greater than 100 parts per billion. Said glucomannan solutions have application in nutritional, therapeutic, and energy fields.

Abstract: A deodorant composition comprising a metal oxide; a primary emollient; and at least one wax with a melting point above 50° C.: wherein the composition is anhydrous and aluminum-free; and wherein the composition has a pH greater than about 8.0 at 60 minutes as measured by the pH Release Test Method.

Abstract: The present invention relates to a long-lasting medical product for protecting or treating a lesion in the gastrointestinal tract. The medical product includes a protective covering, wherein the medical product upon application at and about the site of the lesion adheres to the gastrointestinal tissue and is capable of remaining at and about the site of the lesion for a time sufficient to allow the lesion to heal or be treated.

Abstract: One aspect of the present invention provides an anti-obesity agent, an anti-dementia agent, a deodorant, an anti-aging agent, an anti-glycation agent, an anti-type I allergy agent, a hypotensive agent, a flavor improving agent, a muscle enhancing agent, and a bone metabolism improving agent which contain a bagasse decomposition extract as an active ingredient.

Abstract: The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

Abstract: The invention relates to a chewable medicated composition comprising simethicone as the sole active ingredient, and at least one gelling agent.

Abstract: Medaide is the only product of its kind that provides a band-aid strategically developed with a medicine carrier reservoir that can be easily puncture to release medication onto an affected skin site. This unprecedented product is uniquely designed with a durable adhesive skin color semi-transparent band-aid to complement diverse users and comes individually packed for easy transport and to preserve the sanitization of each covering.

Abstract: One aspect of the present invention provides an anti-obesity agent, an anti-dementia agent, a deodorant, an anti-aging agent, an anti-glycation agent, an anti-type I allergy agent, a hypotensive agent, a flavor improving agent, a muscle enhancing agent, and a bone metabolism improving agent which contain a bagasse decomposition extract as an active ingredient.

Abstract: The present invention relates to a long-lasting medical product for protecting or treating a lesion in the gastrointestinal tract. The medical product includes a protective covering, wherein the medical product upon application at and about the site of the lesion adheres to the gastrointestinal tissue and is capable of remaining at and about the site of the lesion for a time sufficient to allow the lesion to heal or be treated.

Abstract: Described herein are zirconium oxychloride clusters comprising zirconium oxychloride and a basic amino acid. Personal care compositions comprising the same, and methods of making and using the same are also described.

Abstract: Described herein are the use of fluid complex coacervates that produce solid adhesives in situ to anchor medical devices such as catheters in a blood vessel. The anchored devices permit the targeted delivery of bioactive agents. The anchored devices can perform as an embolic agent by reducing or preventing blood flow in the vessel. Additionally, the embolic produced from the solid adhesive produced in situ can also include one or more bioactive agents that can be released in a controlled manner.

Abstract: The present invention relates to a new delivery system for nutritional ingredients (nutraceuticals). These nutritional ingredients are useful for gut and metabolic health in monogastric animals, especially in humans.

Abstract: A hair coloring composition that includes about 5 to 25 wt. % of a first monosaccharide having 2 to 4 carbon atoms, up to about 10 wt. % of a second monosaccharide having 2 to 4 carbon atoms, about 0.1 to 5 wt. % of a surfactant, and about 0.1 to 5 wt. % of a delivery agent, each based on a total weight of the hair coloring composition. A method for coloring hair, that involves applying the hair coloring composition onto the hair, and optionally applying heat to the hair at a dyeing temperature of 30 to 205° C.

Abstract: The present invention is in the field of personal care compositions, in particular compositions comprising antiperspirant actives. The present invention more particularly relates to compositions which do not contain the conventional and well established aluminium based actives, yet exhibit similar efficacy. This is achieved through use of an active which is a complex of a zinc salt with a ? amino acid in an anhydrous carrier.

Abstract: According to the invention there is provided inter alia a medical device for delivering a therapeutic agent to a tissue, the device having a solid surfactant-free particulate coating layer applied to a surface of the device, the coating layer comprising a therapeutic agent and at least one non-polymeric organic additive which is hydrolytically stable; wherein at least a proportion of the particulate coating layer comprising the therapeutic agent and the at least one organic additive melts as a single phase at a lower temperature than the melting point of the therapeutic agent and the at least one organic additive when in pure form; wherein the therapeutic agent is paclitaxel; and wherein the therapeutic agent, when formulated in the coating layer, is stable to sterilization.

Abstract: The disclosure provides a method of producing a pharmaceutical composition. The method comprises (a) dissolving an active pharmaceutical ingredient (API) in a liquid vehicle to form a liquid medicament; (b) contacting the liquid medicament with a pharmaceutical carrier; (c) contacting the composition comprising the liquid medicament and pharmaceutical carrier with a pharmaceutical coating material to form a liqui-mass composition; and (d) pelletising the liqui-mass composition to form the pharmaceutical composition.

Abstract: The present invention relates to a polyhedral complex, a cosmetic agent having the polyhedral complex formed therein, and a cosmetic composition comprising same, the polyhedral complex comprising: a thixotropic polyhedral structure formed of a plurality of flat-type substances; and a mixture of a functional substance and a solvent accommodated in the polyhedral structure. Furthermore, the present invention relates to a method for manufacturing the cosmetic agent, the method comprising: mixing the plurality of flat-type substances, the functional substance, and the solvent; and high-pressure spraying the mixture, and to a method for stabilizing the functional substance in the cosmetic agent.