Patents Examined by Patricia L. De Santis
  • Hybrid DNA conferring osmotic tolerance
    Patent number: 4594323
    Abstract: Non-conjugative episomes characterized by having a mutated proBA region are provided for conferring osmotic tolerance on osmotically sensitive hosts. The mutated DNA sequence overproduces at least one enzyme in the biosynthetic pathway for an amino acid which imparts the desired osmotic tolerance.Cell lines E. coli CSH26 were deposited at the A.T.C.C. on Sept. 20, 1982 and given accession number 39202.
    Type: Grant
    Filed: January 12, 1984
    Date of Patent: June 10, 1986
    Assignee: The Regents of the University of California
    Inventors: Laszlo N. Csonka, Raymond C. Valentine