Abstract: The invention relates to a method for producing an antioxidatively active extract which can be used in particular for stabilizing foodstuffs and cosmetic agents. According to the method, non-enzymatically browned grain germs, or a mixture containing non-enzymatically browned grain germs, is/are extracted using a solvent or solvent mixture (e.g. ethanol or an ethanolic mixture) having an ETN value ranging from 0.6 to 0.8, and the extracting agent is then optionally separated off. The invention also relates to a method for stabilizing unbrowned grain germs in which these unbrowned grain germs are mixed with non-enzymatically browned grain germs.
Type:
Grant
Filed:
March 14, 2001
Date of Patent:
May 27, 2003
Assignee:
Universität Hannover
Inventors:
Yasser El Saharty, Ulrich Krings, Ralf Günther Berger
Abstract: A method for the treatment of symptoms related to normal hormonal variations in women during fertile, peri- and post-menopausal age, by the administering of a composition comprising, as active ingredients, a water and/or fat-soluble cytosolic extract of pollen, optionally combined with Royal Jelly and Vitamin E.
Type:
Grant
Filed:
August 31, 2001
Date of Patent:
May 27, 2003
Assignee:
Natumin Pharma AB
Inventors:
Kaj Winther, Christer Hedman, Lars Kärnerud
Abstract: A composition for enhancing the fertility and/or libido of a male mammal is described as well as methods of enhancing fertility and libido. The composition described includes the polyamines spermine, spermidine and according to one embodiment also includes selenium.
Abstract: The invention provide a method for accelerating the clearance of hemorrhagic blood from the vitreous humor of a mammalian eye without producing toxicity to the eye, the method comprising contacting with the vitreous humor an amount of a solution which contains hyaluronidase to provide a dose of at least 1 International Unit of hyaluronidase, the hyaluronidase being in purified form possessing intravitreal hemorrhage-clearing activity and being free from impurities that produce toxicity to the eye.
Type:
Grant
Filed:
December 2, 1999
Date of Patent:
April 22, 2003
Assignee:
ISTA Pharmaceuticals, Inc.
Inventors:
Hampar L. Karageozian, Vicken H. Karageozian, Maria Cristina Kenney, Jose Luis Gutierrez Flores, Gabriel Arturo Carpio Aragon, Anthony B. Nesburn
Abstract: The invention relates to a composition for to assist in the achievement of optimal cardiovascular health. The composition addresses various concerns including low antioxidant status, low levels of essential fatty acids, magnesium, potassium, and elevated levels of homocysteine. It is designated to treat and prevent heart disease and stroke.
Abstract: A human cell growth medium formulation for culturing human cells of neural crest origin, most preferably corneal endothelial cells, or for accelerating the growth and proliferation of human cells of neural crest origin is disclosed. The formulation for the nutrient medium of the invention includes nerve growth factor, preferably at a concentration of 1-100 ng/ml and most preferably 20 ng/ml. The growth medium formulation preferably also includes epidermal growth factor (preferably at a concentration of 1-200 ng/ml and most preferably 5 ng/ml).
Type:
Grant
Filed:
September 14, 2001
Date of Patent:
April 1, 2003
Assignee:
The Schepens Eye Research Institute, Inc.
Abstract: The present invention relates to a dietary supplement for the treatment of obesity, including both weight loss and reduction of weight gain. Pursuant to the invention, a decoction of a herbal mixture, comprising rhubarb, red saga root, astragalus, turmeric, and dried ginger and various combinations thereof, provides therapeutic weight loss as well as lipid reduction and change body composition. The invention includes methods of manufacture and administration and also includes the herbal decoction in various forms of administration and in combination with food.
Abstract: Pesticidal compositions for the control of household pests, such as cockroaches and ants contain peppermint oil (or cornmint oil), optionally blended with one or more plant essential oils. The present invention is also directed to synergistic pesticidal compositions containing peppermint oil optionally blended with at least one plant essential oils. Further, the present invention is directed to a method for controlling household pests, such as cockroaches and ants, by applying a pesticidally-effective amount of the inventive pesticidal composition to a locus where pest control is desired.
Abstract: A method for enhancing growth hormone production and release, for appetite suppression, or both, in a subject in need thereof. The method comprises administering to the subject an effective amount of a first composition, wherein the first composition increases cholinergic tone and growth hormone synthesis, and the second composition inhibits somatostatin. The first composition may be a combination of an acetylcholinesterase inhibitor and Vitamin E D-&agr;-succinate, whereas the second composition may be a salt of cysteamine and an alkali buffer, or may be pantothenic acid and an alkali metal salt. A two-part composition comprising the first and second compositions as also disclosed.
Abstract: The present invention relates to a method for preparation of plant extract powder and oral compositions containing plant extract powder prepared by the same. More particularly, the present invention could provide a method for preparation of plant extract powder comprising the steps of (a) loading a plant extract having activities of prevention of and treatment for periodontal diseases or tooth decay into a porous powder carrier; (b) coating said carrier's surface with a water-insoluble coating agent and oral compositions containing plant extract powder prepared by the above described method which have an excellent periodontal diseases preventing effect and tooth decay preventing effect.
Type:
Grant
Filed:
May 3, 2001
Date of Patent:
January 7, 2003
Assignee:
Pacific Corporation
Inventors:
Hyun Soo Moon, Byung Ryeul Lee, Key Hyun Lee
Abstract: It is an object of the invention to improve a conventional soil percolation technique to thereby provide a method of enriching and isolating decomposing bacteria decomposing an organochlorine agricultural chemical PCNB which is difficult to decompose, in a short time period, and to provide decomposing bacteria for efficiently processing PCNB. To practice the method, an enrichment soil layer 2 is formed by mixing a soil containing an organochlorine agricultural chemical PCNB with a fragmented porous material having an infinite number of micropores and at the same time a greater adsorptivity for adsorbing PCNB than the soil, and an inorganic salt medium 3 containing a carbon and nitrogen source, the carbon and nitrogen source being formed by only PCNB, is circulated through the enrichment soil layer 2, thereby enriching the aerobic bacteria Burkholderia cepacia in the fragmented porous material.
Type:
Grant
Filed:
March 24, 2000
Date of Patent:
December 24, 2002
Assignee:
National Institute for Agro-Environmental Science Independent
Administrative Institute
Abstract: A composition and method for treating some symptoms associated with cognitive and emotional conditions wherein the composition comprises at least one butyrate alkali metal or alkaline earth metal salt of n-butyric acid, preferably, a mixture of calcium and magnesium butyrate.
Abstract: Osteoarthritis is treated by a composition containing both apocynin and an inhibitor of inducible nitric oxide synthase such as curcumin. Further components such as boswellic acids, glucosamine, acetylcysteine and boron further enhance the beneficial effect of apocynin and curcumin.
Type:
Grant
Filed:
September 14, 2000
Date of Patent:
December 10, 2002
Assignee:
N.V. Nutricia
Inventors:
Ivo Maria Franciscus Graus, Hobbe Friso Smit
Abstract: Dislcosed are methods and compositions for producing weight loss in a mammal by administration of a composition containing a weight loss effective amount of a noradrenaline stimulating compound such as ephedrine, mahuang (a plant source of ephedrine alkaloids), citrus aurantium (bitter orange), synephrine, norephedrine, psuedophedrine, a methylxanthine, such as caffeine or guarana, and a botanical COX inhibitor such as resveratrol polygonum cuspidatum, scutellaria baicalensis, turmeric, curcumin, rosmary, green tea, ocimum sanctum (holy basil), or ginger, instead of an NSAID such as aspirin, and optionally a free fatty acid reducing compound. The thermogenic formula is coupled with a growth hormone stimulating formulation containing L-arginine or L-omithine, L-lysine, and a free fatty acid reducing agent such as nicotinic acid. The thermogenic formula would preferably be administered in the daytime, and the growth hormone producing formula at nighttime.
Abstract: The present invention provides a therapeutic agent for treatment of diabetes and hyperlipemia, especially a therapeutic agent for treatment of type II diabetes mellitus, which comprises as the active ingredient a neurotrophic factor such as BDNF (brain-derived neurotrophic factor), ligands of trkB or trkC receptors, NGF, NT-3, NT-4/5, CNTF, GDNF, HGF, etc. Different from conventional oral hypoglycemic agents being mainly used in the treatment of type II diabetes mellitus, the agent of the present invention exhibit blood lipid regulating effects and body fat accumulation regulating effects, in addition to the blood glucose regulating effects. Thus, the agent of the present invention are novel, and can reduce the risk factors in diabetes accompanied by hyperlipemia or obesity, without using any other agent.
Abstract: The invention relates to a nutritional intervention composition that enhances and extends satiety in a calorically efficient manner. In particular, the invention contains protein, long chain fatty acids, calcium, soluble and insoluble fibers to stimulate CCK and prevent its subsequent inactivation and inhibition. By stimulating CCK and extending satiety the method is useful for the treatment of overweight individuals, individuals with Type II diabetes and individuals with bulimia.
Abstract: This invention provides an anti-cancer composition of high purity beta-elemene extracted from plant sources. This invention also provides for the use of the composition as well as a low cost method to prepare it by multiple passes through the precision distillation tower.
Abstract: A composition for treating diabetes is disclosed. The composition includes fenugreek and bile from the gallbladder of ruminant mammals. The composition is used to treat diabetes through regular periodic dose administration.