Patents Examined by Paul J. Zucker
  • Combretastatin A-1 phosphate and combretastatin B-1 phosphate prodrugs
    Patent number: 7078552
    Abstract: The present invention relates to the syntheses and structural elucidation of Combretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrugs and the utilization of those prodrugs in the treatment of neoplastic diseases. The prodrugs described herein have the structure: Combretastin A-1 Phosphate Prodrug (I) and Combretastin B-1 Phosphate Prodrug (II).
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: July 18, 2006
    Assignee: Arizona Board of Regents
    Inventors: George R. Pettit, John W. Lippert, III