Patents Examined by Paul Killos
  • Patent number: 6803481
    Abstract: The present invention concerns the use of compounds of the Formula (I) for treating different types and symptoms of acute and chronic pain, especially non neuropathic inflammatory pain in mammals. The pain to be treated may be e.g. chronic inflammatory pain, rheumatoid arthritis pain and/or secondary inflammatory osteoarthritic pain. The compounds show an antinociceptive profile and differ from classical analgesics like opioids and non-steroidal anti-inflammatory drugs (NSAIDS) and are useful as specific analgesics.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: October 12, 2004
    Assignee: Schwarz Pharma AG
    Inventor: Norma Selve
  • Patent number: 6750365
    Abstract: The present invention relates to a process for the dissociation of allophanates, in which a thermal dissociation is carried out in a reaction vessel and the gaseous dissociation products obtained are removed from the reaction vessel using an inert carrier gas or the vapor of a liquid as stripping medium and are condensed.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: June 15, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Gerhard Laqua, Matthias Klötzer, Volker Krase, Peter Pfab, Joachim Pfeffinger, Andreas Schmidt
  • Patent number: 6740774
    Abstract: A process for preparing N-acyl derivatives of the formula I, in which the substituents independently of one another have the following meanings: X is CH(OR3)2, COOR3; R1 is hydrogen, C1-C12-alkyl, aryl, unsubstituted or substituted; R2 is hydrogen, C1-C12-alkyl, aryl, unsubstituted or substituted; R3 is C1-C12-alkyl, which comprises reacting a carboxamide R1—CONH2 of the formula II with a glyoxal monoacetal derivative of the formula III, in the presence of a carboxylic acid R4—COOH of the formula IV where R4=C1-C12-alkyl, where the substituents R1 to R3 are as defined above, is described.
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: May 25, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Joachim Paust, Hansgeorg Ernst, Reinhard Kaczmarek, Hagen Jaedicke
  • Patent number: 5710314
    Abstract: Compounds of formula I ##STR1## and possible isomers and isomeric mixtures thereof, wherein a)X is CH.sub.2 F or CHF.sub.2 ;Y is CH andZ is OMe, orb)X is CH.sub.2 F or CHF.sub.2 ;Y is a nitrogen atom andZ is OMe or NHCH.sub.3,and wherein alsom is 0, 1, 2, 3, 4 or 5 andU represents identical or different substituents selected from halogen, cyano, nitro, C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkenyloxyiminomethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkoxyiminomethyl, C.sub.1 -C.sub.2 haloalkyl, C.sub.1 -C.sub.2 haloalkoxy, unsubstituted or substituted phenyl, unsubstituted or substituted phenoxy and unsubstituted or substituted benzyl or represents substituents at two adjacent positions of the phenyl ring of formula I that define a fused hydrocarbon bridge so as to form a larger hydrocarbon ring having up to 14 carbon atoms, are suitable for controlling and preventing microorganisms, insects and Acarina on plants.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: January 20, 1998
    Assignee: Novartis Corporation
    Inventors: Albert Pfiffner, Stephan Trah
  • Patent number: 5384424
    Abstract: The present invention relates to a process for the selective preparation of 4,4-methylene-bis-(N-phenylalkylcarbamate) which comprises condensing N-phenylalkylcarbamate with a methylating agent in the presence of an acidic ion-exchange resin or an aqueous acid as a catalyst and a non polar aprotic solvent and filtrating a condensation product at a temperature greater than the melting point of N-phenylalkylcarbamate to separate 4,4-methylene-bis-(N-phenylalkylcarbamate).
    Type: Grant
    Filed: June 25, 1992
    Date of Patent: January 24, 1995
    Assignee: Lucky Limited
    Inventors: Jae S. Oh, Eung J. Kim
  • Patent number: 4209460
    Abstract: Pure acetyl chloride containing less than 1 ppm of phosphorus is produced. To this end, crude acetyl chloride containing phosphorus compounds is intimately contacted with 1 to 20 liters of gaseous chlorine per liter of liquid crude acetyl chloride and the acetyl chloride so contacted with chlorine is subjected to fractional distillation.
    Type: Grant
    Filed: December 28, 1978
    Date of Patent: June 24, 1980
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Alexander Ohorodnik, Eberhard Auer, Klaus Gehrmann
  • Patent number: 3944603
    Abstract: Production of propionic acid and propionic anhydride with the repression of polyketone formation by carboxylating ethylene utilizing a catalyst system essentially composed of an iridium compound in the substantial absence of added halide components.
    Type: Grant
    Filed: May 7, 1974
    Date of Patent: March 16, 1976
    Assignee: Monsanto Company
    Inventor: Donald E. Morris