Patents Examined by Paul M. Coughlin, Jr.
  • Patent number: 4477448
    Abstract: Novel compounds of formula I, ##STR1## in which R.sub.1 is hydrogen, alkyl, phenylalkyl, carbalkoxyalkyl, acyl, carboxyalkyl, alkoxyalkyl, hydroxyalkyl, cyanoalkyl, or carbamoylalkyl,R.sub.2 is hydrogen, pivaloyloxymethyl or the residue of an easily splittable ester grouping,R.sub.3 is a pyrazolyl radical, unsubstituted or mono- or di-substituted by alkyl, phenyl, alkoxy, alkylthio, carboxy, carboxyalkyl, carbamoyl, carbamoylalkyl, alkylsulphonyl, azido, acylamino, hydrazino, acylhydrazino alkylidenehydrazino, phenylidenehydrazino, in which the phenyl nucleus is unsubstituted or substituted by NH.sub.2, lower alkoxy or lower alkyl, furylidenehydrazino, carbalkoxy or a group R.sub.5 R.sub.6 N--, in which R.sub.5 and R.sub.6 are the same or different and are hydrogen or alkyl, provided that the nitrogen atoms and the 4-position of the pyrazole nucleus are either unsubstituted or substituted by alkyl, phenyl, or carbalkoxy, andR.sub.
    Type: Grant
    Filed: June 21, 1982
    Date of Patent: October 16, 1984
    Assignee: Sandoz Ltd.
    Inventors: Helmut Hamberger, Hans Fliri
  • Patent number: 4434100
    Abstract: 7-Aryl-5H-dibenz[c,e]azepines, e.g., those of the formula ##STR1## wheren: Ar'=phenyl, furyl, thienyl, pyridyl or phenyl subst. by alkyl, OH, alkoxy, halo or CF.sub.3 ;R'=halo or CF.sub.3N-oxides or salts thereof are anxiolytic, tranquilizing and anti-convulsant agents.
    Type: Grant
    Filed: November 14, 1980
    Date of Patent: February 28, 1984
    Assignee: Ciba-Geigy Corporation
    Inventor: Heinz W. Gschwend
  • Patent number: 4000129
    Abstract: Novel 6-substituted amino-penicillanic sulfoxide silyl esters useful as intermediates for the preparation of 7-aminodesacetoxycephalosporanic acids derivatives.
    Type: Grant
    Filed: August 26, 1974
    Date of Patent: December 28, 1976
    Assignee: Koninklijke Nederlandsche Gist-en Spiritusfabriek N.V.
    Inventor: Jan Verweij