Patents Examined by Paul Prehilic
  • Calcification mitigation of implantable bioprostheses
    Patent number: 4838888
    Abstract: A process for treating biological tissue prior to implantation to mitigate the calcification of the tissue following implantation comprises incorporating acetylsalicylic acid into the tissue in an amount effective to reduce calcification of the tissue after it is implanted. In accordance with one embodiment, the process involves convalently binding the acetylsalicylic acid to the tissue via a coupling agent.
    Type: Grant
    Filed: April 17, 1987
    Date of Patent: June 13, 1989
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Aws S. Nashef