Abstract: A device includes a microfluidic channel structure on a substrate and a first resistive structure on the substrate to control the temperature of at least the substrate. The first resistive structure is separate from, and independent of the, microfluidic channel structure. In some instances, the device includes a second resistive structure.

Abstract: The present disclosure provides a particle analyzer and a particle test control method and device thereof. A method comprises, after acquiring a diluted sample, preserving a part of the diluted sample, and monitoring whether a pore blocking event occurs during a counting process; when the pore blocking event occurs, suspending the test of the sample, and performing an unblocking operation; and after the unblocking operation is completed, controlling a liquid addition system to again acquire the preserved part of the sample from a reaction cell or a tube of the liquid addition system and inject it into a counting cell, and then re-counting the sample in the counting cell by an impedance method.

Abstract: The invention is an interior vessel of a simulation cabinet, with at least two hook-shaped fastening elements being arranged at the interior vessel for fastening at a housing of the simulation cabinet, and a simulation cabinet comprising such an interior vessel and a housing, with the housing showing engagement elements, which can be engaged by the hook-shaped fastening elements.

Abstract: Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network. In some embodiments, positioning of the droplets can take place in the order in which they are introduced into the microfluidic network (e.g., sequentially) without significant physical contact between the droplets. Because of the little or no contact between the droplets, there may be little or no coalescence between the droplets. Accordingly, in some such embodiments, surfactants are not required in either the fluid sample or the carrier fluid to prevent coalescence of the droplets. Structures and methods described herein also enable droplets to be removed sequentially from the predetermined regions.

Abstract: A simple and robust on-chip blood plasma separation device is provided. The device is configured to integrate with downstream detection modules and provides sample-to-answer microfluidic POC diagnostics devices.

Abstract: A sample processing kit including a centrifugal microfluidic component and a collection component detachably fitted into the microfluidic component is provided. Upon the application of the sample processing kit, target molecules or cells may be separated and collected by the collection component for further experimentation.

Abstract: The invention relates to a sensing device for a portable apparatus, in particular a portable telecommunication device or a wearable device, the sensing device comprising an acoustic wave sensing mechanism, like a microphone; and a gas sensing mechanism, wherein the acoustic wave sensing mechanism and the gas sensing mechanism are integrally formed. The invention furthermore relates to an electronic device comprising such a sensing device. In addition, a method is provided that allows calibrating a gas volume based on an output signal of an acoustic wave sensing mechanism.

Abstract: A quick, non-destructive and inexpensive test is disclosed to determine whether a portion of a structure made of 5XXX Aluminum alloy is sensitized. Unlike the current sensitization tests, this test can be performed by non-skilled personnel without complicated procedures and equipment. Since the test is non-destructive, it does not require the removal material from the structure. This feature makes the test particularly attractive for in situ applications such as for use on existing structures like ships. The test requires the application of an indicating chemical to the surface of the material being tested. The indicating chemical has a pre-determined pH which may be either acidic or alkaline. The indicating chemical also contains an pH indicator of pre-determined value. After a short period of time has elapsed, the percentage of pH color change observed from the indicating chemical can be used to determine whether the sample is sensitized or not.

Abstract: Single-sided optoelectrowetting (SSOEW)-configured substrates are provided, as well as microfluidic devices that include such substrates. The substrates can include a planar electrode, a photoconductive (or photosensitive) layer, a dielectric layer (single-layer or composite), a mesh electrode, and a hydrophobic coating. Fluid droplets can be moved across the hydrophobic coating of such substrates in a light-actuated manner, upon the application of a suitable AC voltage potential across the substrate and the focusing of light into the photoconductive layer of the substrate in a location proximal to the droplets. Walls can be disposed upon the substrates to form the microfluidic devices. Together the walls and substrate can form a microfluidic circuit, through which droplets can be moved.

Abstract: An analytical system and method for periodically monitoring an injection water distribution pipeline for the presence and concentration of formaldehyde or other aldehyde-functional biocide includes pumps, one of which provides a predetermined volume of injection water drawn from the pipeline at a sampling point and another of which provides a predetermined volume of a reagent, preferably a buffered solution of dimedone, from a reagent storage vessel, wherein the injection water and reagent are mixed and then heated in a chamber to a predetermined temperature to promote formation of any reaction products. The heated reaction mixture is passed to a detection cell and exposed to light of predetermined wavelength which, in accordance with the Hantzsch reaction, molecules having an aldehyde functional group that reacted with dimedone produce a fluorescence-emitting reaction product, the intensity of which is measured and compared to data previously obtained from standard aldehyde-containing solutions.

Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, may be controlled via hydraulic pressure.

Abstract: Microfluidic devices that are configured to use centrifugal forces to bias particles into one or more capture regions based on their individual sizes are described.

Abstract: A test tube carrier for transporting test tubes in a laboratory automation system is presented. The test tube carrier comprises a base body and at least three centering fingers attached to the base body. The centering fingers are distributed about a central axis (A). Each centering finger comprises an elongate, bent resilient element and a strut having a higher stiffness than the resilient element. The struts extend in parallel to the central axis (A). A first end of the associated resilient element is fixedly attached to the strut at an upper position and a second end of the resilient element contacts the strut at a lower position between the base body and the upper position. A laboratory distribution system having a number of test tube carriers, and a laboratory automation system comprising a laboratory distribution system are also presented.

Abstract: A microfluidic system for analyzing a sample solution includes a division chamber for accommodating an input volume of the sample solution. The division chamber has a plurality of partial volume segments for accommodating a plurality of partial volumes of the sample solution, which partial volumes can be used for detection reactions. The microfluidic system also has a displacing device configured to divide the input volume into the plurality of partial volumes.

Abstract: A method for measuring concentrations of blood cell components is provided. The method comprises: obtaining a blood sample from a subject, the blood sample comprising red blood cells (RBCs), white blood cells (WBCs), and platelets (PLTs); mixing the blood sample with a non-lysing aqueous solution to form a sample mixture comprising a predetermined tonicity; passing the sample mixture through a flow cell; emitting light towards the flow cell; measuring an amount of light absorbed by the RBCs; measuring an amount of light scattered by WBCs, and PLTs; determining a concentration of each of the RBCs, WBCs, and PLTs present in the sample mixture from the measured amount of light absorbed by the RBCs and scattered by the WBCs and PLTs.

Abstract: A biochip device for detection of biologic molecules in a fluidic sample is disclosed in this invention. The biochip device comprises a plastic substrate, an IC chip, a sealing cover and a vacuum bag. The plastic substrate comprises a variety of microfluidic structures including an inlet region of loading the fluidic sample, a separation structure, a microfluidic channel, a structure for slowing the flow of the fluidic sample, a reaction region, a detection zone groove, and a closed area for collecting the fluidic sample. The plastic substrate is embedded with an IC chip and covered by a sealing cover made of polydimethylsiloxane, which is encapsulated by a vacuum bag, whereby the microfluidic structures in the plastic substrate are kept in vacuum state inside the vacuum bag.

Abstract: A punching device for processing samples applied to a sample card is provided. The punching device includes a movable gripper unit and an image capturing device and at least one punching head having a punch and a lower die. The punching head has a receiving opening into which a sample card is introducible by means of the movable gripper unit and is positionable relative to the punching head. The punching device further includes a punching drive which is couplable or coupled to the punch of the punching head. The punching device further includes a receiving plate supporting the receiving container and having a light source illuminating at least a part of the receiving plate. The light source is arranged such that at least a part of the receiving container located on the receiving plate can be illuminated from the direction of the receiving plate.

Abstract: A technique relates to a machine for sorting. A removable cartridge includes a nanofluidic module. The removable cartridge includes an input port and at least two output ports. The nanofluidic module is configured to sort a sample fluid. A holder is configured to receive the removable cartridge. A pressurization system is configured to couple to the input port of the removable cartridge. The pressurization system is configured to drive the sample fluid into the nanofluidic module for separation to the at least two output ports.

Abstract: An aerosol-generating system for oral or nasal delivery of a generated aerosol to a user is provided, including a heater element configured to heat an aerosol-forming substrate to generate an aerosol; a power source; a controller configured to control operation of the heater element, the controller being configured to detect a change in air flow past the heater element: a first data storage recording detected changes in airflow past the heater element and data relating to the operation of the heater element; a second data storage including a database relating changes in airflow and data relating to the operation of the heater element to the properties of the aerosol delivered to the user; and an indicator coupled to the second data storage configured to indicate to the user a property of the aerosol delivered to the user.

Abstract: A specimen processing cartridge includes a reservoir having a fluid inlet, an elastic diaphragm, and a fluid outlet. The reservoir is operable to receive a volume of liquid from the fluid inlet, and the fluid outlet is positioned along a fluid flow path between the reservoir and a downstream reservoir. The cartridge includes a dissolvable membrane that occludes flow through the fluid outlet when the dissolvable membrane is in a first, undissolved state, and that permits flow from the reservoir to the downstream reservoir when in a second, dissolved state. The elastic diaphragm is operable to pressurize the reservoir upon receiving the volume of liquid when the dissolvable membrane is in the first, undissolved state, and is operable to contract and propel at least a portion of the volume of liquid from the reservoir to the downstream reservoir when the dissolvable membrane is in the second, dissolved state.