Abstract: A cardioplegia delivery device and method of use for delivering warm or cold cardioplegia fluid to the heart of a patient. The delivery device includes an air chamber having a housing with an integral pressure relief valve for diversion of cardioplegia fluid if the fluid pressure within the housing exceeds a predetermined pressure. The air chamber includes a membrane and one-way valve located near the top of the housing for removal of air from the cardioplegia fluid. The delivery device may include an integral heat exchanger for controlling the temperature of the cardioplegia fluid.