Abstract: Provided herein is a derivative of 2-deoxy-2-amino-4-O-phophono-D-glucopyranose, which is derived from lipid A, of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are a member in a pair selected from the group consisting of those indicated in a following table:______________________________________ Com- pound No. R.sub.1 R.sub.2 ______________________________________ I(R,R) --O--CO--(CH.sub.2).sub.12 --CH.sub.3 --O--CO--(CH.sub.2).sub.12 --CH.sub.3 II --O--CO--(CH.sub.2).sub.12 --CH.sub.3 --OH II(R,R) --O--CO--(CH.sub.2).sub.12 --CH.sub.3 --OH II(S,S) --O--CO--(CH.sub.2).sub.12 --CH.sub.3 --OH III --OH --O--CO--(CH.sub.2).sub.12 --CH.sub.3 III(R,R) --OH --O--CO--(CH.sub.2).sub.12 --CH.sub.3 III(S,S) --OH --O--CO--(CH.sub.2).sub.12 --CH.sub.3 IV(R) --H --O--CO--(CH.sub.2).sub.12 --CH.sub.3 ______________________________________The compounds of this invention include those of rectus and sinister configurations and act as mitogens for polyclonal B cells.