Abstract: A control system is disclosed for use with a locomotive. The control system may have a component located onboard the locomotive, the component having a first state and a second state. The control system may also have an operator input device located onboard the locomotive and used to manually toggle operation of the component between the first and second states, and at least one sensor located onboard the locomotive and configured to generate a signal associated with a condition of the locomotive. The control system may also have an offboard controller located remotely from the locomotive and being configured to selectively override the operator input device and toggle operation of the component between the first and second states based on the signal.