Patents Examined by Peter Kulkosky
  • Patent number: 5464612
    Abstract: (A) A clad powdery or granular preparation of a medicinally active ingredient and (B) a powdery or granular ion exchanger such as a cation exchange resin are blended to prepare a solid preparation. The active ingredient includes .beta.-lactam antibiotics having a basic group. The clad powdery or granular preparation includes not only coated preparation wherein the active ingredient or preparation is coated but also a variety of preparations in which the contact of the active ingredient with the ion exchanger is suppressed or inhibited. Polymers such as a water-soluble polymer, an enteric polymer and so on can be used as the coating agent for the coated preparation. The using amount of the ion exchanger is about 10 to 5,000 parts by weight per 100 parts by weight of the active ingredient. Said solid preparation can remarkably decrease the unpleasant taste and odor of the active ingredient such as bitterness, being excellent in dissolution property and absorbability of the active ingredient.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: November 7, 1995
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Hiroshi Matoba, Shinji Ohmori, Hiroyoshi Koyama, Toshio Kashihara
  • Patent number: 5411731
    Abstract: A bath additive composition comprises an aluminum salt and a carbonate and makes the pH of bath water 8 or higher but less than 9 when the bath additive composition is dissolved in the bath water. The bath additive composition does not damage bathtubs, bath water heating devices, or the skin of users, provides a refreshing feel to the skin after bathing, and has an excellent ability of suppressing perspiration.
    Type: Grant
    Filed: July 21, 1993
    Date of Patent: May 2, 1995
    Assignee: Kao Corporation
    Inventors: Norihiro Tanaka, Kazuyuki Okui, Yasuhiro Doi, Hirotaka Sato, Hidenori Yorozu
  • Patent number: 5378753
    Abstract: Alumina hydrate particles have a high surface area and low dispersity and may have a low soluble soda content. They may be made by milling a liquid suspension of alumina hydrate, subjecting the milled suspension to classification into coarse and fine fractions, recycling the coarse fraction to the mill and recycling the fine fraction to the classification stage. A narrow particle size distribution is obtained.
    Type: Grant
    Filed: August 24, 1990
    Date of Patent: January 3, 1995
    Assignee: Alcan International Ltd.
    Inventor: Stephen C. Brown
  • Patent number: 5378456
    Abstract: An antitumor polymeric composition comprising an anthracene antitumor compound, particularly mitoxantrone, covalently conjugated to, or admixed with, a divinyl ether-maleic anhydride (MVE) copolymer and methods of treating solid tumors and inducing regression of leukemia cell growth in mammals by administering such compositions.
    Type: Grant
    Filed: March 25, 1993
    Date of Patent: January 3, 1995
    Assignee: American Cyanamid Company
    Inventor: Hwei-Ru Tsou
  • Patent number: 5320838
    Abstract: A smooth, greaseless skin ointment especially prepared for irritated skin, which protects, adheres and simultaneously is easily washable without causing skin damage. The ointment base is a blend of polyethylene glycols. It is combined with a bioadhesive which works synergistically to allow the blended ointment base to adhere to wet and moist areas, while not being so adhesive as to cause damage when removed in washing. Specifically a blend of polyethylene glycol polymers is prepared to provide good skin feel and drag, a polyvinyl ether anhydride salt bioadhesive is added and a polyvinylpyrrolidone is also used as a dispersant, and feces and urine toxicant binder. Optionally minor amounts of dimethicone can be added.
    Type: Grant
    Filed: December 21, 1992
    Date of Patent: June 14, 1994
    Assignee: Pro Cure Products, Ltd.
    Inventor: William H. Woller
  • Patent number: 5310549
    Abstract: A solid iodine concentrate composition comprising an iodine complex, and a solidifier wherein said iodine complex comprises a complexing agent and an iodine source present in a ratio of at least 1.5:1.
    Type: Grant
    Filed: August 31, 1989
    Date of Patent: May 10, 1994
    Assignee: Ecolab Inc.
    Inventor: Sandra L. Bull
  • Patent number: 5209922
    Abstract: This invention relates to an antifungal block copolymer of poly(vinyl lactam) having the formula ##STR1## where m has a value of from 1 to 3 and from about 15 to about 25 wt. % of a quaternized amino alkyl acrylamide comonomer wherein the quaternizing anion is in part halide --O--CO(CH.sub.2).sub.s CH.dbd.CHZ wherein s has a value of from 4 to 14 and Z is hydrogen or a C.sub.1 to C.sub.4 alkyl radical, which copolymer is comprised of the following units ##STR2## wherein m has a value of from 1 to 3; p has a value of from 1 to 5; r has a value of from 2 to 6; each of X and Y is hydrogen or a C.sub.1 to C.sub.4 alkyl and each of R.sub.1, R.sub.2 and R.sub.3 is C.sub.1 to C.sub.4 alkyl. The invention also relates to the use of the above polymers as antifungal agents.
    Type: Grant
    Filed: March 19, 1992
    Date of Patent: May 11, 1993
    Assignee: ISP Investments Inc.
    Inventors: John J. Merianos, Herbert A. Lieberman, Paul Garelick
  • Patent number: 5165920
    Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions.
    Type: Grant
    Filed: March 27, 1991
    Date of Patent: November 24, 1992
    Assignee: Union Oil Company of California
    Inventors: James A. Green, II, Donald C. Young
  • Patent number: 5104787
    Abstract: A defined serumfree medical solution for applications in Ophthalmology, that contains one or more cell nutrient supplements which maintains and enhances the preservation of eye tissues, including human corneal tissues at low temperatures (2.degree. C. to 15.degree. C.). This solution is composed of a defined aqueous nutrient and electrolyte solution, supplemented with a glycosaminoglycan(s), a deturgescent agent(s), an energy source(s), a buffer system(s), an antioxidant(s), membrane stabilizing components, antibiotic(s), ATP precursors and nutrient cell supplements.
    Type: Grant
    Filed: March 5, 1990
    Date of Patent: April 14, 1992
    Inventors: Richard L. Lindstrom, Debra Skelnik
  • Patent number: 4869906
    Abstract: A resorbable porous tricalcium phosphate, in which the pores are sealed with a filler mixture of an antibiotic and a filler, in particular an amino acid, is particularly advantageous for use in the preparation of bone cements.
    Type: Grant
    Filed: April 17, 1987
    Date of Patent: September 26, 1989
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Elvira Dingeldein, Helmut Wahlig, Manfred Wotschokowsky, Gu Moddelmog
  • Patent number: 4424327
    Abstract: A rapid setting .alpha.-cyanoacrylate based adhesive composition having an improved polymerization catalyst therein.
    Type: Grant
    Filed: March 10, 1981
    Date of Patent: January 3, 1984
    Assignee: Terason GmbH
    Inventors: Karl Reich, Heinz Tomaschek, Georg Busch
  • Patent number: 4327191
    Abstract: Process for preparing anion exchange resins comprising polymerizing a vinyl aromatic compound having at least one alkyl group containing about 1 to 3 carbon atoms, alone or mixed with a copolymerizable monomer, optionally in the presence of a mineral support, followed by brominating the alkyl groups of the resulting polymer by means of an N-bromoamide or an N-bromoimide, and then aminating the brominated product obtained. The resulting anion exchange resins are useful in the chemical, pharamaceutical, food, and metallurgical industries.
    Type: Grant
    Filed: August 18, 1980
    Date of Patent: April 27, 1982
    Assignee: Rhone-Poulenc Industries
    Inventors: Adrien Dromard, Ramanadin
  • Patent number: 4315995
    Abstract: A process for preparing a cation-exchange resin is disclosed. The process comprises:(a) treating a chlorine-containing material, which is the distillation residue obtained by chlorinating or oxychlorinating a C.sub.2 -C.sub.40 hydrocarbon, with a sulfonating agent,(b) treating the admixture of step (a) with water and an organic solvent until the product shows a substantially neutral pH, and(c) removing the volatile materials to obtain a solid material which is suitable for use as a cation-exchange resin.
    Type: Grant
    Filed: August 22, 1980
    Date of Patent: February 16, 1982
    Assignee: Conoco Inc.
    Inventor: Charles M. Starks
  • Patent number: 4311799
    Abstract: A basic copolymer whose main chain is cross-linked which comprises about 6 to about 98% by weight of recurring units of Formula (A) or (B), ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, each represents a hydrogen atom or a hydrocarbon group selected from the group consisting of C.sub.1-20 alkyl groups, C.sub.3-10 cycloalkyl groups, C.sub.3-8 alkenyl groups, C.sub.6-15 aryl groups, C.sub.7-12 arylalkyl groups and C.sub.1-15 aminoalkyl groups; and X is an acid radical, and about 2 to about 94% by weight of cross-linked units based on the total weight of the recurring units of Formula (A) or (B) and the cross-linked units and, if desired, up to about 92% by weight of units of a monoethylenically unsaturated monomer or a conjugated monomer based on the total weight of the recurring units of Formula (A) or (B), the cross-linked units and the units of the monoethylenically unsaturated monomer or the conjugated monomer.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: January 19, 1982
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventors: Tetsuya Miyake, Kunihiko Takeda, Akihiko Ikeda
  • Patent number: 4222922
    Abstract: An improved warp size for filament yarn is provided consisting essentially of polyvinyl alcohol, alkyl phenoxy (or cresoxy) ethoxyethyl dimethylbenzyl ammonium chloride and a plasticizer such as glycerol or urea, which when applied to filament yarn from aqueous solution provides excellent weaving efficiency and ease of removal combined with low shedding in the loom.
    Type: Grant
    Filed: December 27, 1978
    Date of Patent: September 16, 1980
    Assignee: E. I. Du Pont De Nemours and Company
    Inventor: Richard W. Rees
  • Patent number: 4186086
    Abstract: The cured reaction product of a polyalkylenepolyamine and a polyepoxide is useful as a weak base ion exchange resin. For example, the reaction of triethylenetetramine and diglycidyl ether of bisphenol A forms a weak base resin having an excellent total weak base capacity.
    Type: Grant
    Filed: June 26, 1978
    Date of Patent: January 29, 1980
    Assignee: The Dow Chemical Company
    Inventor: Eldon L. Ward
  • Patent number: 4167610
    Abstract: Ion exchange resins of the poly(allylamine) type which comprise an aralkyl radical or a saturated aliphatic radical, and which may be made by reacting an allylamine type polymer with an organic dihalo compound so as to crosslink it.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: September 11, 1979
    Assignee: ICI Australia Limited
    Inventors: Brian A. Bolto, Kurt H. Eppinger
  • Patent number: 4166109
    Abstract: An anti-solar polymer has in the macromolecular chain thereof at least one unit of the formula ##STR1## wherein F is a residue derived from an aromatic compound. The anti-solar polymer can also be one having in the macromolecular chain thereof at least one unit of the formula ##STR2## wherein F.sub.1 is ##STR3## These polymers have the ability to absorb wave lengths of light in the range of about 280-315 millimicrons. The polymers are employed in a cosmetic composition.
    Type: Grant
    Filed: August 18, 1976
    Date of Patent: August 28, 1979
    Assignee: L'Oreal
    Inventors: Bernard Jacquet, Christos Papantoniou, Pierre Dufaure, Claude Mahieu
  • Patent number: 4148774
    Abstract: Anisotropic dopes composed of an aromatic polyamide in oleum are produced by polymerizing an aromatic diamine such as p-phenylenediamine sulfate and an aromatic diacid such as terephthalic acid in sulfur trioxide.
    Type: Grant
    Filed: April 7, 1978
    Date of Patent: April 10, 1979
    Assignee: Monsanto Company
    Inventor: Frank M. Silver
  • Patent number: 4148773
    Abstract: A plasticized polycarbonate composition comprising in admixture a high molecular weight aromatic carbonate polymer and a minor amount of a siloxane plasticizer.
    Type: Grant
    Filed: December 28, 1977
    Date of Patent: April 10, 1979
    Assignee: General Electric Company
    Inventors: Victor Mark, Phillip S. Wilson