Patents Examined by Peter Kulkosky
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Patent number: 5464612Abstract: (A) A clad powdery or granular preparation of a medicinally active ingredient and (B) a powdery or granular ion exchanger such as a cation exchange resin are blended to prepare a solid preparation. The active ingredient includes .beta.-lactam antibiotics having a basic group. The clad powdery or granular preparation includes not only coated preparation wherein the active ingredient or preparation is coated but also a variety of preparations in which the contact of the active ingredient with the ion exchanger is suppressed or inhibited. Polymers such as a water-soluble polymer, an enteric polymer and so on can be used as the coating agent for the coated preparation. The using amount of the ion exchanger is about 10 to 5,000 parts by weight per 100 parts by weight of the active ingredient. Said solid preparation can remarkably decrease the unpleasant taste and odor of the active ingredient such as bitterness, being excellent in dissolution property and absorbability of the active ingredient.Type: GrantFiled: April 28, 1994Date of Patent: November 7, 1995Assignee: Takeda Chemical Industries, Ltd.Inventors: Hiroshi Matoba, Shinji Ohmori, Hiroyoshi Koyama, Toshio Kashihara
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Patent number: 5411731Abstract: A bath additive composition comprises an aluminum salt and a carbonate and makes the pH of bath water 8 or higher but less than 9 when the bath additive composition is dissolved in the bath water. The bath additive composition does not damage bathtubs, bath water heating devices, or the skin of users, provides a refreshing feel to the skin after bathing, and has an excellent ability of suppressing perspiration.Type: GrantFiled: July 21, 1993Date of Patent: May 2, 1995Assignee: Kao CorporationInventors: Norihiro Tanaka, Kazuyuki Okui, Yasuhiro Doi, Hirotaka Sato, Hidenori Yorozu
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Patent number: 5378456Abstract: An antitumor polymeric composition comprising an anthracene antitumor compound, particularly mitoxantrone, covalently conjugated to, or admixed with, a divinyl ether-maleic anhydride (MVE) copolymer and methods of treating solid tumors and inducing regression of leukemia cell growth in mammals by administering such compositions.Type: GrantFiled: March 25, 1993Date of Patent: January 3, 1995Assignee: American Cyanamid CompanyInventor: Hwei-Ru Tsou
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Patent number: 5378753Abstract: Alumina hydrate particles have a high surface area and low dispersity and may have a low soluble soda content. They may be made by milling a liquid suspension of alumina hydrate, subjecting the milled suspension to classification into coarse and fine fractions, recycling the coarse fraction to the mill and recycling the fine fraction to the classification stage. A narrow particle size distribution is obtained.Type: GrantFiled: August 24, 1990Date of Patent: January 3, 1995Assignee: Alcan International Ltd.Inventor: Stephen C. Brown
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Patent number: 5320838Abstract: A smooth, greaseless skin ointment especially prepared for irritated skin, which protects, adheres and simultaneously is easily washable without causing skin damage. The ointment base is a blend of polyethylene glycols. It is combined with a bioadhesive which works synergistically to allow the blended ointment base to adhere to wet and moist areas, while not being so adhesive as to cause damage when removed in washing. Specifically a blend of polyethylene glycol polymers is prepared to provide good skin feel and drag, a polyvinyl ether anhydride salt bioadhesive is added and a polyvinylpyrrolidone is also used as a dispersant, and feces and urine toxicant binder. Optionally minor amounts of dimethicone can be added.Type: GrantFiled: December 21, 1992Date of Patent: June 14, 1994Assignee: Pro Cure Products, Ltd.Inventor: William H. Woller
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Patent number: 5310549Abstract: A solid iodine concentrate composition comprising an iodine complex, and a solidifier wherein said iodine complex comprises a complexing agent and an iodine source present in a ratio of at least 1.5:1.Type: GrantFiled: August 31, 1989Date of Patent: May 10, 1994Assignee: Ecolab Inc.Inventor: Sandra L. Bull
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Patent number: 5209922Abstract: This invention relates to an antifungal block copolymer of poly(vinyl lactam) having the formula ##STR1## where m has a value of from 1 to 3 and from about 15 to about 25 wt. % of a quaternized amino alkyl acrylamide comonomer wherein the quaternizing anion is in part halide --O--CO(CH.sub.2).sub.s CH.dbd.CHZ wherein s has a value of from 4 to 14 and Z is hydrogen or a C.sub.1 to C.sub.4 alkyl radical, which copolymer is comprised of the following units ##STR2## wherein m has a value of from 1 to 3; p has a value of from 1 to 5; r has a value of from 2 to 6; each of X and Y is hydrogen or a C.sub.1 to C.sub.4 alkyl and each of R.sub.1, R.sub.2 and R.sub.3 is C.sub.1 to C.sub.4 alkyl. The invention also relates to the use of the above polymers as antifungal agents.Type: GrantFiled: March 19, 1992Date of Patent: May 11, 1993Assignee: ISP Investments Inc.Inventors: John J. Merianos, Herbert A. Lieberman, Paul Garelick
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Patent number: 5165920Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions.Type: GrantFiled: March 27, 1991Date of Patent: November 24, 1992Assignee: Union Oil Company of CaliforniaInventors: James A. Green, II, Donald C. Young
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Patent number: 5104787Abstract: A defined serumfree medical solution for applications in Ophthalmology, that contains one or more cell nutrient supplements which maintains and enhances the preservation of eye tissues, including human corneal tissues at low temperatures (2.degree. C. to 15.degree. C.). This solution is composed of a defined aqueous nutrient and electrolyte solution, supplemented with a glycosaminoglycan(s), a deturgescent agent(s), an energy source(s), a buffer system(s), an antioxidant(s), membrane stabilizing components, antibiotic(s), ATP precursors and nutrient cell supplements.Type: GrantFiled: March 5, 1990Date of Patent: April 14, 1992Inventors: Richard L. Lindstrom, Debra Skelnik
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Patent number: 4869906Abstract: A resorbable porous tricalcium phosphate, in which the pores are sealed with a filler mixture of an antibiotic and a filler, in particular an amino acid, is particularly advantageous for use in the preparation of bone cements.Type: GrantFiled: April 17, 1987Date of Patent: September 26, 1989Assignee: Merck Patent Gesellschaft Mit Beschrankter HaftungInventors: Elvira Dingeldein, Helmut Wahlig, Manfred Wotschokowsky, Gu Moddelmog
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Patent number: 4424327Abstract: A rapid setting .alpha.-cyanoacrylate based adhesive composition having an improved polymerization catalyst therein.Type: GrantFiled: March 10, 1981Date of Patent: January 3, 1984Assignee: Terason GmbHInventors: Karl Reich, Heinz Tomaschek, Georg Busch
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Patent number: 4327191Abstract: Process for preparing anion exchange resins comprising polymerizing a vinyl aromatic compound having at least one alkyl group containing about 1 to 3 carbon atoms, alone or mixed with a copolymerizable monomer, optionally in the presence of a mineral support, followed by brominating the alkyl groups of the resulting polymer by means of an N-bromoamide or an N-bromoimide, and then aminating the brominated product obtained. The resulting anion exchange resins are useful in the chemical, pharamaceutical, food, and metallurgical industries.Type: GrantFiled: August 18, 1980Date of Patent: April 27, 1982Assignee: Rhone-Poulenc IndustriesInventors: Adrien Dromard, Ramanadin
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Patent number: 4315995Abstract: A process for preparing a cation-exchange resin is disclosed. The process comprises:(a) treating a chlorine-containing material, which is the distillation residue obtained by chlorinating or oxychlorinating a C.sub.2 -C.sub.40 hydrocarbon, with a sulfonating agent,(b) treating the admixture of step (a) with water and an organic solvent until the product shows a substantially neutral pH, and(c) removing the volatile materials to obtain a solid material which is suitable for use as a cation-exchange resin.Type: GrantFiled: August 22, 1980Date of Patent: February 16, 1982Assignee: Conoco Inc.Inventor: Charles M. Starks
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Patent number: 4311799Abstract: A basic copolymer whose main chain is cross-linked which comprises about 6 to about 98% by weight of recurring units of Formula (A) or (B), ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, each represents a hydrogen atom or a hydrocarbon group selected from the group consisting of C.sub.1-20 alkyl groups, C.sub.3-10 cycloalkyl groups, C.sub.3-8 alkenyl groups, C.sub.6-15 aryl groups, C.sub.7-12 arylalkyl groups and C.sub.1-15 aminoalkyl groups; and X is an acid radical, and about 2 to about 94% by weight of cross-linked units based on the total weight of the recurring units of Formula (A) or (B) and the cross-linked units and, if desired, up to about 92% by weight of units of a monoethylenically unsaturated monomer or a conjugated monomer based on the total weight of the recurring units of Formula (A) or (B), the cross-linked units and the units of the monoethylenically unsaturated monomer or the conjugated monomer.Type: GrantFiled: July 2, 1979Date of Patent: January 19, 1982Assignee: Asahi Kasei Kogyo Kabushiki KaishaInventors: Tetsuya Miyake, Kunihiko Takeda, Akihiko Ikeda
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Patent number: 4222922Abstract: An improved warp size for filament yarn is provided consisting essentially of polyvinyl alcohol, alkyl phenoxy (or cresoxy) ethoxyethyl dimethylbenzyl ammonium chloride and a plasticizer such as glycerol or urea, which when applied to filament yarn from aqueous solution provides excellent weaving efficiency and ease of removal combined with low shedding in the loom.Type: GrantFiled: December 27, 1978Date of Patent: September 16, 1980Assignee: E. I. Du Pont De Nemours and CompanyInventor: Richard W. Rees
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Patent number: 4186086Abstract: The cured reaction product of a polyalkylenepolyamine and a polyepoxide is useful as a weak base ion exchange resin. For example, the reaction of triethylenetetramine and diglycidyl ether of bisphenol A forms a weak base resin having an excellent total weak base capacity.Type: GrantFiled: June 26, 1978Date of Patent: January 29, 1980Assignee: The Dow Chemical CompanyInventor: Eldon L. Ward
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Patent number: 4167610Abstract: Ion exchange resins of the poly(allylamine) type which comprise an aralkyl radical or a saturated aliphatic radical, and which may be made by reacting an allylamine type polymer with an organic dihalo compound so as to crosslink it.Type: GrantFiled: November 21, 1977Date of Patent: September 11, 1979Assignee: ICI Australia LimitedInventors: Brian A. Bolto, Kurt H. Eppinger
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Patent number: 4166109Abstract: An anti-solar polymer has in the macromolecular chain thereof at least one unit of the formula ##STR1## wherein F is a residue derived from an aromatic compound. The anti-solar polymer can also be one having in the macromolecular chain thereof at least one unit of the formula ##STR2## wherein F.sub.1 is ##STR3## These polymers have the ability to absorb wave lengths of light in the range of about 280-315 millimicrons. The polymers are employed in a cosmetic composition.Type: GrantFiled: August 18, 1976Date of Patent: August 28, 1979Assignee: L'OrealInventors: Bernard Jacquet, Christos Papantoniou, Pierre Dufaure, Claude Mahieu
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Patent number: 4148773Abstract: A plasticized polycarbonate composition comprising in admixture a high molecular weight aromatic carbonate polymer and a minor amount of a siloxane plasticizer.Type: GrantFiled: December 28, 1977Date of Patent: April 10, 1979Assignee: General Electric CompanyInventors: Victor Mark, Phillip S. Wilson
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Patent number: 4148774Abstract: Anisotropic dopes composed of an aromatic polyamide in oleum are produced by polymerizing an aromatic diamine such as p-phenylenediamine sulfate and an aromatic diacid such as terephthalic acid in sulfur trioxide.Type: GrantFiled: April 7, 1978Date of Patent: April 10, 1979Assignee: Monsanto CompanyInventor: Frank M. Silver