Abstract: A process is described for the improved synthesis of the optically pure C.sub.10 -C.sub.24 fragment of the macrolide structure of the immunosuppressant FK-506. This compound is also useful as an intermediate for preparing FK-506 derivatives.

Abstract: Herbicidally active pyrroles of the formula ##STR1## wherein R.sup.1 represents C.sub.1-4 alkyl, or one R.sup.1 together with the other R.sup.1 forms tetramethylene or butenylene,X represents hydrogen or halogen,Y represents O or S,n represents 0 or 1,R.sup.2 represents hydrogen or an organic radical.

Abstract: A veterinary composition is disclosed which is suitable against endoparasites and which contains as active ingredients:(a) alpha-(cyano)-3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane-carboxylic a cid-3-phenoxybenzyl ester or any isomeric mixture thereof; and(b) 5(6)-propylthio-2-benzimidazolyl-methylcarbamate, wherein the weight ratio of the two respective compounds is 1:1 to 1.5:1, in combination with a carrier that is inert for veterinary purposes.

Abstract: Novel pyridazinamine derivatives having antiviral activity, compositions containing these compounds as active ingredient, and a method of destructing viruses or preventing the growth thereof in warm-blooded animals suffering from diseases caused by these viruses. Processes for preparing said compounds and compositions.

Abstract: Compounds useful for the treatment of patients suffering from muscle spasms of the formula (I) ##STR1## in which R represents the radical ##STR2## in which R.sub.1, in any position on the phenyl nucleus, represents a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, identical or different each represents a hydrogen atom, a linear alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or form together with the nitrogen atom to which they are joined, a heterocyclic radical optionally containing another heteroatom, or NO.sub.2, or OR', R' representing hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms, or aryl containing up to 14 carbon atoms, or an SR.sub.4 or S(O)R.sub.5 radical, R.sub.4 and R.sub.5 representing a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon atoms, or R represents naphthyl, optionally substituted by an R.sub.

Abstract: Perfluorocarboxylic acid fluorides represented by the formula A-B, wherein A is either ##STR1## and B stands for a perfluoro-di-substituted amino group, and perfluoro(dialkylaminopropenes) represented by the formula A"-B", wherein A" stands for ##STR2## and B" has the same meaning as B defined above, are novel compounds. Methods for the production of these novel compounds are also disclosed.

Abstract: The present invention relates to 1-(4-aminophenyl-2)-hexamethyleniminopropanone and its pharmaceutically acceptable addition salts.These products are useful in therapy on account of their antidepressant effects on the CNS and their immunological properties.

Abstract: The present invention relates to the use of 6-halo-4-quinolone derivatives and pharmaceutical compositions comprising them as active ingredient, for the preparation of a medicament for the therapeutical application in rheumatoid arthritis.Quinolone derivatives can be intra-articularly administered and act on different points of the pathological process of rheumathoid arthritis without local and general toxicity.

Abstract: The invention relates to the use of N-3-(5-trifluoromethylpyridyl-2-oxy)phenyl-N'-benzoylureas of formula I ##STR1## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.2 alkoxy, C.sub.1 -C.sub.2 alkylthio, C.sub.1 -C.sub.2 alkyl or halogen,R.sub.2, R.sub.3 and R.sub.5 are independently of each other hydrogen or halogen, andR.sub.4 is hydrogen, C.sub.1 -C.sub.2 alkyl or halogen,for controlling helminths, especially nematodes and trematodes, in domestic animals and productive livestock.

Abstract: Novel aromatic diamines which are useful as chain extenders for urethane and urea polymers are compounds corresponding to the formula: ##STR1## wherein two of the R, R', and R" substituents are alkyl groups containing 1-6 carbons and the other substituent is a hydrocarbylthio group containing 1-6 carbons.

Abstract: Novel substituted aryloxyureas, processes for their production, and herbicides comprising them as active ingredients are provided.The substituted aryloxyureas exhibit an excellent herbicidal efficacy against weeds when applied, for example, to the weeds in a wide range of period from a preemergence stage to a growth stage.The substituted aryloxyureas of the invention have the excellent advantage of maintaining high safety on crops or crop plants in spite of their herbicidal efficacy.

Abstract: Organic halogen compounds in which one or more halogen atoms are covalently bonded to the carbon are subjected to reductive dehalogenation by reaction with a hydrocarbon in the presence of carbon at elevated temperatures with formation of a hydrogen halide, by a process in which the dehalogenation is carried out in the presence of iron powder or an iron compound as a cocatalyst, at from 100.degree. to 450.degree. C.

Abstract: Novel 7H-benzo[b]pyrazino[1,2-d]pyrrolo[3,2,1-jk][1,4]benzodiazepines, processes for the preparation thereof, and a method of treating depression utilizing compounds or compositions thereof are disclosed.