Abstract: Electrosurgical forceps for efficiently severing of hollow organs, in particular vessels. The electrosurgical forceps have a first branch and a second branch for gripping the hollow organ. The forceps have at least one neutral electrode on the second branch, at least one first coagulation electrode and a second coagulation electrode that is disposed on the first branch for applying a first HF current by means of the coagulation electrode, and at least one cutting device, which is arranged between the coagulation electrodes in order to sever the hollow organ in a cutting region. The cutting device has a cutting electrode for applying a second HF current between the cutting and neutral electrodes. The coagulation electrodes are arranged spaced apart from one another in such a way that the first HF current does not flow through or only a minor amount of the same flows through the cutting region.

Abstract: Treatment of heart failure in a patient by electrically modulating both the sympathetic and parasympathetic autonomic cardiac nerve fibers that innervate the patient's heart at an extravascular site in the pericardial space of the heart. The extravascular site is any suitable single location inside the chest cavity that carries both sympathetic and parasympathetic cardiac nerves such as the cardiac plexus or the pericardial transverse sinus or any two separate extravascular sites with one site carrying predominantly sympathetic cardiac nerves and the other site carrying predominantly parasympathetic cardiac nerves for electrically modulating the balance of autonomic cardiac nerve control.

Abstract: A method of operating a cardiac therapy system to deliver cardiac resynchronization therapy (CRT) pacing that includes pacing both ventricles or pacing only the left ventricle is described. Delivery of the CRT pacing to one or both ventricles is scheduled for a cardiac cycle. If an intrinsic depolarization of a ventricle is detected during a pacing delay of the ventricle, then the scheduled CRT pacing to the ventricle is inhibited for the cycle. The intrinsic interval of the ventricle, such as the intrinsic atrioventricular interval concluded by the intrinsic depolarization, is measured. During a subsequent cardiac cycle, the pacing delay of the ventricle is decreased to be less than or equal to the measured intrinsic interval. Capture of the ventricle is verified after pacing is delivered during the subsequent cardiac cycle.

Abstract: The present invention generally relates to implantable medical devices, such as pacemakers, and, in particular, to a method and an implantable medical device capable of detecting the presence of noise caused by external noise sources. Voltages and/or impedances are measured over one or several electrode configurations. Based on the measured voltages and/or impedances, noise parameters are calculated, which are compared with reference values to detect the presence of noise. In another aspect of the invention, at least two different electrode configurations with different noise pick-up areas are used in the measurement. Relations between the noise parameters of the at least two vectors are calculated and compared with reference relations to detect the presence of noise.

Abstract: In a method and apparatus for supplying wireless energy to a medical device implanted in a patient, wireless energy is transmitted from an external energy source located outside a patient and is received by an internal energy receiver located inside the patient, for directly or indirectly supplying received energy to the medical device. An energy balance is determined between the energy received by the internal energy receiver and the energy used for the medical device, and the transmission of wireless energy is then controlled based on the determined energy balance. The energy balance thus provides an accurate indication of the correct amount of energy needed, which is sufficient to operate the medical device properly, but without causing undue temperature rise.

Abstract: Apparatus is provided that includes one or more electrodes, configured to be applied to a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, or a lesser deep petrosal nerve; and a control unit, configured to drive the electrodes to apply electrical stimulation to the site, and configure the stimulation to excite nervous tissue of the site at a strength sufficient to induce at least one neuroprotective occurrence selected from the group consisting of: an increase in cerebral blood flow (CBF), and a release of one or more neuroprotective substances, and insufficient to induce a significant increase in permeability of a blood-brain barrier (BBB).

Abstract: A family of minimally-invasive surgical (MIS) cardiac interventional tools with tactile feedback based upon cardiac mechanical data and physiologic parameters derived from sensors positioned upon the tools are configurable for optimal placement of an end-effector to provide acute cardiac resuscitation and/or remote cardiovascular intervention for a subject. A haptic interface (e.g., a haptic handle, haptic glove or a simulated haptic heart) provides a clinician with real, not virtual, interaction with the cardiovascular anatomy (including intrathoracic organs) of the subject to optimize end-effector placement. The MIS tools optionally include webbed blade portions for exploration of extracardiac or intrathoracic spaces.

Abstract: The ANS of a subject is continuously monitored to obtain the sympathetic nervous system (SNS) and parasympathetic nervous system (PSNS) components of the autonomous nervous system while an external stimulus is applied to the subject having a frequency that sweeps across a frequency band. The stimulus may be a vibration, flickering light or sound. The ANS is determined to have entered into a state of homeostasis when the SNS component equals the PSNS component. The value of frequency that corresponds to the state of homeostasis is selected as the fundamental frequency of the subject for use in subsequent treatment protocols.

Abstract: This document relates to methods and materials involved in delivering therapies to target tissue (e.g., a peripheral nerve). For example, methods and materials for placing and subsequently using leads to deliver electrical and/or drug therapies to target tissues (e.g., nerves and/or arteries) are provided.

Abstract: An electrosurgical instrument for minimally invasive surgery, the instrument including two gripping parts which can be brought together into a gripping direction or moved apart counter to the gripping direction. At least one gripping part includes three or more electrically conductive sections, electrically insulated relative to each other. Each electrically conductive section may be separately connected to a high frequency (RF) current generator such that each electrically conductive section can be configured in various electrical configurations by the RF current generator.

Abstract: Various methods and apparatuses are disclosed that concern delivering electrical stimulation to a brain at a plurality of different stimulation frequencies, sensing one or more bioelectrical signals, and identifying a bioelectrical resonance response of the brain to the electrical stimulation. The bioelectrical resonance response may be identified based on a parameter of oscillation of the one or more bioelectrical signals and indicative of resonance of an area of the brain to one stimulation frequency of the plurality of stimulation frequencies. A stimulation frequency parameter for a therapy may be set based on the identified bioelectrical resonance response, wherein the stimulation frequency parameter is set at or near the one stimulation frequency.

Abstract: Protocols are provided for the use of frequency specific microcurrent in conjunction with dental or orthodontic procedures to treat or prevent inflammation induced complications. Specific protocols are disclosed for use in conjunction with gingival surgery and chronic periodontitis, implant/osseous periodontal surgery, general post operative trauma, pulpal trauma, pulpal inflammation, root canal post op, chronic osteonecrosis, osteonecrosis surgery post op, orthodontic pain prevention, and orthodontic mid-adjustment procedures.

Abstract: An exemplary method includes positioning a lead in a patient where the lead has a longitudinal axis that extends from a proximal end to a distal end and where the lead includes an electrode with an electrical center offset from the longitudinal axis of the lead body; measuring electrical potential in a three-dimensional potential field using the electrode; and based on the measuring and the offset of the electrical center, determining lead roll about the longitudinal axis of the lead body where lead roll may be used for correction of field heterogeneity, placement or navigation of the lead or physiological monitoring (e.g., cardiac function, respiration, etc.). Various other methods, devices, systems, etc., are also disclosed.

Abstract: The present invention relates to an apparatus and a corresponding method for non-invasive intracardiac electrocardiography (ECG) by use of a magnetic and electrically conducting interference device (210). An MPI-based ECG mapping technique is proposed, wherein an interference device (210), e.g. an electrically conducting rod containing soft magnetic material, is steered through the vessel system and the heart using magnetic fields generated by a magnetic particle imaging (MPI) system so that the ECG signals measured in parallel are influenced. Using appropriately adapted evaluation means (153) this influence of the interference device (210) on the ECG signals can be evaluated to gain spatially resolved information about the electrical heart activity.

Abstract: Methods and apparatuses are described for monitoring synchronization of two or more brain areas and delivering an electrical therapy to the brain to facilitate synchronization of the two or more brain areas. The electrical therapy can be titrated to improve synchronization between the two or more areas of the brain based on the one or more signals, the synchronization between the two or more areas of the brain occurring in response to the patient being exposed to external sensory stimulus, wherein the electrical therapy does not independently cause activation of either of the two or more areas of the brain.

Abstract: A system for controlling a position of a patient's tongue includes attaching at least one electrode to the patient's Hypoglossal nerve and applying an electric signal through the electrode to at least one targeted motor efferent located within the Hypoglossal nerve to stimulate at least one muscle of the tongue. The system may also include the use of more than one contact to target more than one motor efferent and stimulating more than one muscle. The stimulation load to maintain the position of the tongue may be shared by each muscle. The position of the patient's tongue may be controlled in order to prevent obstructive sleep apnea.

Abstract: An outflow conduit for a cardiac assist pump has a connector at one end comprised of a main sleeve configured to mate with a pump outlet port. A plurality of prongs extend from the sleeve. Each prong has a distal end with a claw and is bendable so that its respective claw expands over a lip and enters the groove of the outlet port. A lock nut is movable between a retracted position and a locking position. In the retracted position, a soft interconnect is obtained. In the locking position, the claws are prevented from escaping over the lip and a hard interconnect is obtained.

Abstract: An active implantable medical device (e.g., implantable pacemaker or defibrillator), for detection of QRS complexes in noisy signals. Functional units (12-16) collect, amplify, prefilter and convert from analog-to-digital an endocardial signal, and digital functional units (18) provide signal processing and analysis of the digitized signal, for delivery of an indicator corresponding to a signal peak detection representative of the presence of a QRS complex in the endocardial signal. A double threshold comparator (30) is employed, receiving as input (28) the digitized signal and outputting (40) the indicator of peak detection when, cumulatively: the amplitude (A) of the input signal exceeds a peak amplitude threshold (SA), and the peak amplitude threshold is exceeded for a period (W) greater than a peak width threshold (SW). The peak amplitude threshold (SA) is a variable adaptive threshold, according to a noise level calculated from the energy (RMS) of the input signal.

Abstract: An implantable medical device includes a sensor configured to generate an endocardial acceleration (EA) signal representative of activity of a patient's heart. The device further includes one or more circuits configured to identify within the EA signal at least one EA signal component corresponding to at least one peak of endocardial acceleration, and extract from the at least one EA signal component at least two characteristic parameters. The one or more circuits are further configured to generate a composite index based on a combination of the at least two characteristic parameters, determine a plurality of values of the composite index for a plurality of pacing configurations, and select a current pacing configuration from among the plurality of pacing configurations based on the plurality of values of the composite index.

Abstract: A method and system are provided for percutaneously gaining access to oxygenated blood with one or more anastomosis devices and pumping such oxygenated blood directly to the aorta adjacent to the right atrium or left atrium via a VAD system. In one embodiment, a VAD system can be implanted with open surgery.