Patents Examined by Phillip A Gray
  • Patent number: 10926066
    Abstract: An inflatable structure for use in biological lumens and methods of making and using the same are disclosed. The structure can have an inflatable balloon encircled by a shell. The shell can have proximal and distal tapered necks, longitudinally-oriented flutes, and apertures at the proximal and distal ends of the shell. The apertures can be recessed in the flutes in the necks. The shell can also have fiber reinforced walls.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: February 23, 2021
    Inventors: Alexander Q. Tilson, Paul J. Dreyer, Mitchell C. Barham, Mark C. Scheeff, Charles S. Love, Garrett J. Gomes, Jonathan Kurniawan
  • Patent number: 10926039
    Abstract: An autoinjector device is disclosed which comprises a body portion and a syringe carrier, for supporting a syringe with a needle at its forward end. The syringe carrier is moveably mounted within the housing such that forward movement relative to the housing may extend the needle from a forward end of the body. The syringe carrier has a latch element arranged to cooperate with a corresponding retention feature of the body portion to releasably hold the syringe carrier in a rearward position within the body potion. A delivery mechanism is arranged to forwardly displace the syringe carrier relative to the housing and to deliver a dose of medicament from the syringe. A shroud assembly is provided at a forward end of the device. The shroud further comprises a locking arrangement which blocks releasing movement of the latch element from the retention feature when the shroud is in a first, forward position and is unlocked when the shroud is in a second, rearward position.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: February 23, 2021
    Assignee: Owen Mumford Limited
    Inventor: Oliver Gould
  • Patent number: 10925688
    Abstract: The invention generally relates to an auxiliary guidewire for an intravascular procedure. The invention provides an auxiliary guidewire that slips over a primary guidewire and can provide a very fine extension beyond the end of the primary guidewire. The primary guidewire can be taken to its limit within the fine vasculature, and the auxiliary guidewire can then extend further into the fine vasculature. The primary guidewire can be taken to a bifurcation. The primary guidewire and the auxiliary guidewire can be sent down separate branches of the bifurcation. A physician can select which of the primary guidewire and the auxiliary guidewire are within the branch that needs to be treated by, for example, consulting an angiography display.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: February 23, 2021
    Inventors: Bret Millett, Joseph Burnett
  • Patent number: 10926026
    Abstract: A peristaltic pump (200) is proposed which comprises a first housing component (210) and a second loading component (230), said second loading component being at least partially contained within said first housing component and being axially movable with respect to said first housing component inside thereto. The second loading component further comprises at least a couple of rollers (235) which engage and squeeze a delivery tube (146) for delivering a fluid passing there through when, in operation, the second loading component is fully snapped into said first housing component. Moreover the second loading component comprises a guiding path (240) for guiding the delivery tube around said at least a couple of rollers towards an exit port (244) which is provided at a distal end surface of the second loading component. The present invention also relates to a patient set and to an injection system comprising said peristaltic pump, as well as to a method of operating said injection system.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: February 23, 2021
    Inventors: Pierre Yves Chassot, Règis Chrétien
  • Patent number: 10918847
    Abstract: An interface device for implantation in a subject includes a tissue integration layer and a crowning element. The tissue integration layer has a porous structure adapted for ingress of tissue to anchor the device when implanted. The crowning element is adapted for epidermal attachment when the device is implanted and is configured such that once implanted, part of the crowning element extends through the epidermis and is accessible from outside the subject's body. The porous structure of the tissue integration layer is interconnected for tissue ingress during implantation.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: February 16, 2021
    Inventor: Gil Stynes
  • Patent number: 10912889
    Abstract: A auto-injector device having a housing (212, 214), a cartridge for containing a medicament, a first needle tip (230) arranged to penetrate said cartridge, a second needle tip (230) for injecting said medicament into a target, said first and second needle tips being in fluid communication, a plunger rod (242) to move said cartridge so as to be pierced by said first needle tip, said plunger rod (242) having a recess (270) in an end thereof, the improvement comprising a battery (258), a printed circuit board (250) electrically communicating with said battery, an electrically conductive element (274) having a first end in electric communication with said battery (258) and printed circuit board (250), a second end within said recess (270) in said plunger rod (242), said second end being electrically insulated, a coil spring (246) surrounding said electrically conductive element and being spaced therefrom, the arrangement being such that when said plunger rod (242) is activated, said second end of said electricall
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: February 9, 2021
    Assignee: Duoject Medical Systems Inc.
    Inventors: Simon Hamel, Sylvain Cloutier, Yan Tremblay, Mathieu Viens
  • Patent number: 10905587
    Abstract: Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: February 2, 2021
    Assignee: OcuJect, LLC
    Inventor: Leonid E. Lerner
  • Patent number: 10898255
    Abstract: The present disclosure provides a plasma catheter including a tubular member; a conductive cylindrical member; a first electrode; and a second electrode. The tubular member defines a longitudinal lumen therethrough and has a proximal portion and a distal portion. The conductive cylindrical member is disposed at the distal portion of the tubular member. The first electrode is embedded in a first side of the tubular member and coupled to the conductive cylindrical member. The second electrode is embedded in a second side of the tubular member diametrically opposed to the first side. The second electrode is offset from the tubular member and aligned with a center axis defined by the conductive cylindrical member.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: January 26, 2021
    Assignee: Covidien LP
    Inventors: Joe D. Sartor, Daniel A. Friedrichs, William Scott Darrow
  • Patent number: 10894123
    Abstract: The invention generally provides a fluid delivery system comprising: a reservoir (7); a pumping chamber (8) having a volume, an inlet valve (48), an outlet valve (49) and a membrane (47); an actuator (20); and a drive member (21). The inlet valve and the outlet valve each comprise a passive normally closed one-way check valve. The inlet valve provides selective fluid communication between the pumping chamber volume and the reservoir. Fluid in the reservoir is at substantially ambient pressure. The drive member is operatively coupled to the pumping chamber membrane. Energising the actuator moves the drive member in reciprocating motion and thereby displaces the membrane to change the pumping chamber volume between a minimum volume and a maximum volume. The pumping chamber volume is held at a pressure above the ambient pressure in the reservoir when the actuator is at rest.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: January 19, 2021
    Assignee: VICENTRA B.V.
    Inventors: Timothy William Oakes, Joseph Cefai
  • Patent number: 10888639
    Abstract: Delivery catheters for in situ forming foams are provided. The catheters include, in various embodiments, coatings, valves, mixing structures, exit ports and combinations of the same.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: January 12, 2021
    Assignee: Arsenal Medical, Inc.
    Inventors: Toby Freyman, Jennifer Mortensen, Jeffrey Groom, II
  • Patent number: 10881847
    Abstract: A neutral pressure split-septum luer access device is described for receiving a luer lock connector. The septum has a plurality of elastomeric columns projecting laterally within a chamber. Each elastomeric column is under sufficient compression so that the columns are bowed and the column strength is reduced by bowing, but the slit sealing force is high. This configuration places the lower portion of the slit in a tightly sealed configuration which is never-the-less receptive to penetration by the male luer which causes the columns to bow further and collapse precipitously with the elastomeric force of the collapsing mass of the columns being carried distally to displace and pop open the central slit distal the tip of the male luer. The septum further provides a transverse separation between the columns and a distal sealing portion so the force of the displacement force to the sealing portion is reduced.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: January 5, 2021
    Inventor: Lawrence Allan Lynn
  • Patent number: 10874827
    Abstract: This disclosure concerns polymer catheter designs incorporating joints that break under tension. The joints are generally formed from two tubular elements comprising two different polymers with dissimilar thermal and/or mechanical characteristics, which are overlapped and exposed to heat and pressure. The disclosure also concerns methods of making and using such catheters, for instance to deliver medical implants.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: December 29, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Pauric John McGowan
  • Patent number: 10869996
    Abstract: An intra-tumoral agent deployment apparatus for diagnosing and delivering targeted, sequential deployment of agents to an endo-bronchial and, or an intra-parenchymal tumor, said apparatus formed of, among other things, an elongated shaft assembly including: at least one lumen; an intra-tumoral probe wire for tumor traversal, slidably interposed there between or slidably disposed between any one of, or combination of the at least one lumen; and wherein the displacement of the intra-tumoral probe wire causes disruption of an endo-bronchial and, or an intra-parenchymal tumor tissue, and, or creating an inlet for deployment of at least a first agent comprising any one of a therapeutic agent and, or a delivery vehicle from the first lumen, and a subsequent second agent comprising any one of a therapeutic agent and, or a binding agent from any one of the first lumen, second lumen, and, or the delivery vehicle.
    Type: Grant
    Filed: October 29, 2016
    Date of Patent: December 22, 2020
    Inventor: Stephen Kuperberg
  • Patent number: 10869832
    Abstract: A substance delivery device comprises a substrate, a plurality of dissolvable supporting structures and a plurality of carriers. The substrate attaches to a tissue. The dissolvable supporting structures are disposed on the substrate. The carriers are disposed on the dissolvable supporting structures and encapsulating substances. The present invention further provides a substance delivery method. The substance delivery device and the substance delivery method of present invention is advantageous for providing sustained release effect and rising the applicability of transdermal or transmucosal delivery techniques.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: December 22, 2020
    Inventors: Mei-Chin Chen, Zih-Yao Lin, Chia-Sui Chen
  • Patent number: 10850029
    Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: December 1, 2020
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, Larry B. Gray, Russell H. Beavis
  • Patent number: 10839669
    Abstract: In some embodiments, a method includes producing, from an adapter, a first wireless signal characterized by a first communication mode with a computing device when a portion of at least one of a medicament delivery device or a simulated medicament delivery is disposed within the adapter. An indication is received when the portion of the medicament delivery device or the simulated medicament delivery device is removed from the adapter. A second wireless signal characterized by a second communication mode with the computing device is produced in response to the indication. The second communication mode is different from the first communication mode. The second communication mode can be, for example, a hold mode, a sniff mode or a park mode.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: November 17, 2020
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Mark J. Licata, Paul F. Meyers, Vaishali Vilas Kamat, Steven David Gardner, Robert George Milner
  • Patent number: 10821232
    Abstract: A needleless syringe for injecting an injection objective substance into an injection target area of a living body is provided. The syringe includes an enclosing unit enclosing the injection objective substance, and an ignition device including an ignition charge and flowing an ignition current so that the ignition charge is combusted. The syringe also includes a pressurizing unit pressurizing the injection objective substance, and a flow passage unit defining a flow passage so that the pressurized injection objective substance is allowed to inject to the injection target area. The pressurizing unit raises a pressure applied to the injection objective substance to a peak pressure for the injection objective substance to penetrate through a surface of the injection target area and then lowers the pressure applied to the injection objective substance to a waiting pressure within 2 msec after the ignition current was allowed to flow to the ignition device.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: November 3, 2020
    Assignee: Daicel Corporation
    Inventor: Shingo Oda
  • Patent number: 10821238
    Abstract: An intradermal injection needle is an intradermal injection needle assembly to be used by piercing the intradermal injection needle into the skin of a living body. The intradermal injection needle has a hollow needle having a blade edge pierceable into the skin and a discharge port of an administration product; and a hub holding the hollow needle. The hollow needle has an outer diameter of 0.15 to 0.20 mm. The discharge port has a length of 0.10 to 0.80 mm in an axial direction of the hollow needle. When the intradermal injection needle is pierced into the skin of the living body, the discharge port thereof is entirely subcutaneously pierceable within a range of 0.20 to 1.00 mm.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: November 3, 2020
    Inventors: Takehiro Ura, Kiyoshi Sakata, Sakiko Tsuneda, Kazunori Koiwai
  • Patent number: 10814106
    Abstract: An IV catheter system may have a catheter component and a needle component. The catheter component may have a catheter hub, a cannula extending distally from the catheter hub, and a push feature extending outward from the catheter hub. The push feature may have an outer surface that receives contact from a digit to move the IV catheter system from an insertion configuration, in which the needle is within the cannula, to a fluid delivery configuration, in which the needle is outside the catheter hub. The needle component may have a needle hub and a needle extending distally from the needle hub along an axis. The push feature may be formed of a flexible material that causes the push feature, in response to pressure exerted on the outer surface by a dressing securing the catheter component to a patient, to deflect the outer surface toward the cannula axis.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: October 27, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Michael Garrison, Bart D. Peterson, Ralph L. Sonderegger, Jonathan Karl Burkholz, Nathan Mitchell
  • Patent number: 10814129
    Abstract: A method and system for delivering a molecule to a specific area of a tissue by controlling temperature and impedance is presented. The method is generally comprised of applying heat to a biological structure, such as cells or tissues, to heat the biological structure to a preset temperature after which at least one electroporation pulse is administered to the biological structure. Impedance is measured as a feedback control mechanism after each pulse and pulse parameters are adjusted accordingly until desired impedance is reached. The system generally comprises an electroporation system capable of generating at least one pulse, measuring impedance and measuring temperature.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: October 27, 2020
    Assignees: University of South Florida, Old Dominion University
    Inventors: Mark Jeffery Jaroszeski, Richard Heller