Abstract: An IV catheter system may have a catheter component and a needle component. The catheter component may have a catheter hub, a cannula extending distally from the catheter hub, and a push feature extending outward from the catheter hub. The push feature may have an outer surface that receives contact from a digit to move the IV catheter system from an insertion configuration, in which the needle is within the cannula, to a fluid delivery configuration, in which the needle is outside the catheter hub. The needle component may have a needle hub and a needle extending distally from the needle hub along an axis. The push feature may be formed of a flexible material that causes the push feature, in response to pressure exerted on the outer surface by a dressing securing the catheter component to a patient, to deflect the outer surface toward the cannula axis.

Abstract: A method for delivery of a pharmaceutical to a subject includes applying a dermal patch to a subject's skin, wherein the dermal patch comprises a reservoir that stores a pharmaceutical and further comprises at least one hollow needle configured for puncturing the skin, actuating the at least one needle to puncture the subject's skin, and causing at least a portion of the stored pharmaceutical to be released from the reservoir for delivery via a lumen of the hollow needle to the subject.

Abstract: Needle assemblies and related methods in which a valve opener is used to push into a valve to open one or more slits on the valve to open the valve. The needle assemblies each includes a needle hub with a needle, a catheter tube with a catheter hub and the valve and valve opener positioned in the interior cavity of the catheter hub. The valve can have a valve skirt and a nose section of the valve opener can locate therein. One or more reliefs can be provided with the valve opener so that an elbow or diagonal section on a needle guard can project from a holding space within the valve opener through the relief.

Abstract: A fluid delivery device comprises a drive unit including an actuator and one or more first features and a cartridge filled with a fluid prior to being inserted into the housing. The cartridge having a fluid reservoir sealed at one end by a movable piston and sealed at another end by a pierceable septum. The cartridge includes one or more second features that are configured to align and mate with the one or more first features allowing the cartridge to be inserted into the drive unit. The piston is moveable by the actuator once the cartridge is inserted into the drive unit.

Abstract: A vascular access wire is disclosed. The vascular access wire includes an elongated core member and a distal tip. The Distal tip comprising a crank configured with a crank distal surface and a crank center of rotation. The crank is configured to rotate about the crank center of rotation when the core member is sufficiently loaded axially and when the crank distal surface is pressed against a wall of a target blood vessel, for triggering or affecting a deflecting and/or a deforming of the core member proximally to the crank.

Abstract: An injection device is disclosed comprising a plunger for expressing medicament from a syringe and a delivery mechanism arranged in use to provide a forward biasing force to urge the plunger from a first rearward position to a second forward position to express a dose from the syringe. A latch arrangement is provided that releasably holds the plunger against the force of the delivery mechanism. The latch arrangement comprising at least two resilient segments which define opposing sections of an aperture within which a rearward end of the plunger is retained in the rearward position. A trigger is provided for releasing the plunger in use, the trigger being arranged to outwardly deflect at least one of the resilient segments such that the aperture is expanded to release the rearward end of the plunger. A method of manufacturing the injection device is also enclosed.

Abstract: A nasogastric tube securing device is an apparatus designed to hold various medical tubes that enter through a person's nose without the use of adhesive tape. A first configuration of the device will attach to an upper lip area of a patient allowing the tube to enter upward into the nasal cavity. A second configuration will attach to the distal end of a nose with a downward facing clip that also holds the tube as it enters the nasal cavity. In both configurations, the clip system used utilizes a plastic sliding track that holds the tube and allows it to slide back and forth, either across the upper lip or side to side along the user patient's nose. The tube clip on the track permits one tube to be exchanged for another one without removing the adhesive, thus eliminating repeating trauma to the skin area. Both clip systems are held in place with Allevyn® Adhesive, Mepilex® silicone foam dressing, or similar product to further reduce skin irritation.

Abstract: A vascular introducer system includes a first vascular introducer having an elongated first deflectable catheter sheath defining a lumen having an interior surface with an inner diameter. A tubular insert having a polygonal cross-section is associated with the interior lumen of the first catheter sheath. The system includes a second vascular introducer having an elongated second deflectable catheter sheath defining an exterior surface with an outer diameter that is less than the inner diameter of the interior surface of the first catheter sheath.

Abstract: A safety intravenous catheter that includes a passive release feature. The catheter assembly includes ready, safe, and released positions. In the release position, a retainer being in a proximal retainer position relative to a collar enables release of the catheter hub from the catheter insertion device. The sharp tip of the insertion needle remains inaccessible in the release position in order to prevent unwanted needle sticks.

Abstract: An assembly is provided for accessing a superior vena cava of a patient without visualization of a vasculature of the patient. A stylet has an elongated body including a core wire disposed within a tubular body, the core wire having a pre-formed shape in a first state and a straightened shape in a second state. A first portion of the core wire has a substantially straight shape in the first state. A second portion of the core wire has a first pre-formed bend in the first state. A third portion of the core wire has a substantially straight shape in the first state. A fourth portion of the core wire has a second pre-formed bend in the first state. A fifth portion of the core wire has a substantially straight shape in the first state and includes a narrow segment that increases deflection of the distal tip.

Abstract: An integrated vascular access device can include strain relief features to minimize the likelihood of the extension tubing becoming kinked during use. These strain relief features can be configured at both ends of the extension tubing to minimize the likelihood of kinking at the interfaces to the catheter adapter and luer adapter. To provide strain relief at the catheter adapter end of the extension tubing, an interface formed of a flexible material can be aligned with an extension of the catheter adapter into which the extension tubing inserts. The interface can be integrated into a stabilization platform or formed separately from a stabilization platform. To provide strain relief at the luer adapter end of the extension tubing, a flexible spacer can be coupled to a distal end of the adapter and have a distal portion that is positioned around the extension tube.

Abstract: A catheter assembly may include a catheter adapter. A body of the catheter adapter may include a distal end, a proximal end, and a first lumen extending through the distal end and the proximal end. The catheter adapter may include a side port, which may extend outwardly from the body. The side port may include a second lumen, which may be perpendicular to the first lumen. The catheter assembly may include a catheter extending distally from the distal end of the body. The catheter assembly may include a valve disposed within the first lumen. The valve may include an outer surface that is cylindrical and may seal the first lumen from the second lumen. The catheter assembly may include a divider disposed with the second lumen. The divider may divide the second lumen into a plurality of openings and may increase a burst value of the valve.

Abstract: A valve is disclosed that has a body with an inlet, an outlet, and a needleless access port coupled to the body. The access port has an interior space and is configured to be actuated by a needleless connector. The inlet is selectively coupled to the outlet through the interior space such that fluid entering the inlet entirely flows through the interior space to the outlet.

Abstract: Needle assemblies and related methods in which a valve opener is used to push into a valve to open one or more slits on the valve to open the valve. The needle assemblies each includes a needle hub with a needle, a catheter tube with a catheter hub and the valve and valve opener positioned in the interior cavity of the catheter hub. The valve can have a valve skirt and a nose section of the valve opener can locate therein. One or more reliefs can be provided with the valve opener so that an elbow or diagonal section on a needle guard can project from a holding space within the valve opener through the relief.

Abstract: A soft grip medical connector comprises a housing with an upstream end, a downstream end and a lumen extending through a central portion thereof. A flexible member comprises a valve portion integrally formed with a sleeve portion. The valve portion is positioned within a section of the housing and is configured to control a flow of fluid through the housing lumen. The sleeve is inverted to envelope at least a portion of the outer surface of the housing. In some embodiments the gripping portion is integrally formed with the valve portion. In some embodiments, the connector is also generally configured to create a positive pressure in a catheter lumen upon removal of a syringe or other medical device from the upstream end of the connector. Methods of making a medical fluid connector generally comprise forming a valve member with a sleeve extending there from, and assembling the valve, sleeve and housing.

Abstract: Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device, tool, or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Some systems described here may be configured to cut or tear the trabecular meshwork with the body of an elongate member located within Schlemm's canal. Other tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.

Abstract: Provided are active agent delivery devices configured to deliver an active agent formulation into or through a mucosal layer in a subject. The active agent delivery devices include a power reservoir configured to eject the active agent formulation at a pressure sufficient to deliver the active agent formulation into or through a mucosal layer in a subject. Methods of using the subject active agent delivery devices are also provided.

Abstract: Apparatuses of the type broadly applicable to numerous medical applications in which it is desirable to insert one or more steerable or non-steerable catheters or similar devices into a working channel of an associated device, such as an endoscope, catheter, etc., or passageway of a patient, are disclosed. The apparatuses may include catheters having a dedicated guide wire channel and one or more of the following: viewing capabilities, a working channel, and auxiliary channels, such as insufflation/irrigation channels. The catheters may include a guide wire channel that is configured to provide the catheter or other device with rapid exchange capabilities.

Abstract: A device, kit, and method for producing medically-deliverable intravenous solution may include supplying a water to a housing, pumping the water through the housing while purifying the water, metering concentrated intravenous solution into the water to create a medically-deliverable intravenous solution, and dispensing the medically-deliverable intravenous solution, such as immediate intravenous infusion to a patient.

Abstract: An intravenous (IV) device, may include a needle; a catheter coaxially formed around the needle; a fluidic path fluidically coupled to a hollow formed through the needle and catheter; and a printed circuit board (PCB), including: a network interface device; a plurality of sensors operatively coupled to the fluidic path to measure a biological characteristic related to a plurality of patient vitals.