Abstract: Various approaches for microbubble-enhanced ultrasound treatment of target tissue include retrieving a treatment plan stored in memory; causing administration of an exogenous agent in accordance with the treatment plan; causing, in accordance with the treatment plan, an ultrasound transducer to transmit ultrasound waves to the target tissue and generate a focus therein in the presence of administered exogenous agent; receiving, from a monitoring system, a measured parameter value indicating a treatment condition in response to administration of the exogenous agent and transmission of the ultrasound waves during treatment; and adjusting the treatment plan based at least in part on the measured parameter value.

Abstract: A nasogastric tube stabilization system is provided. The nasogastric tube stabilization clip includes a clip operatively associated between the first portion and the second portion of nasogastric tube stabilization adhesive, wherein the clip is movable between a clipped condition and an unclipped condition, enabling the first and second portions of nasogastric tube stabilization adhesive to move independently of each other for facilitating treatment of a patient, wherein the nasogastric tube stabilization adhesive portions adhere to a nasogastric tube and the nose of patient, respectively, thereby in the clipped condition the nasogastric tube stabilization system stabilizes the nasogastric tube relative to the patient.

Abstract: A catheter system that is actuatable to a deployed state and includes a catheter body and a dilator positioned at least partially within the lumen of the catheter. A distal end of the dilator can be releasably connected to a distal tip of the catheter body. The dilator can be retractable to expand and invert the distal tip and form a funnel shape in the deployed state.

Abstract: A fixing device of a nasogastric tube contains: an adhesion member, a connection member, and a retainer. The adhesion member includes an adhesive face, a circular column, and an engagement portion. The connection member includes a connecting sheet, a locating post, and a spherical portion. The connecting sheet has a rectangular slot and an annular orifice, such that the annular orifice accommodates the engagement portion of the adhesion member, the rectangular slot slidably receives the circular column of the adhesion member, an end of the connecting sheet proximate to the annular orifice is connected with the locating post, and the other end of the locating post is connected with the spherical portion. The retainer includes a coupling bar and a joining knob. The retainer further includes a clamp section and two press portions. Furthermore, the clamp section has a hollowly circular space defined therein.

Abstract: A puncture visualization device can include a guidewire having a proximal section, a distal section, and a distal tip. The device can include a needle having a needle lumen configured to receive the guidewire. The device can include a lock, and the lock can engage with the guidewire. For instance, engagement of the lock with the guidewire can inhibit relative motion between the guidewire and the needle. The device can include an optical sensor, for example located at the distal tip of the guidewire. The optical sensor can be locked into a position, for instance by the lock. In an example, the device provides a distal field of view from a location within the needle and near a distal end of the needle for visualization to facilitate puncturing a target with the distal end of the needle.

Abstract: A needle protection device may include a hub, a housing disposed within the lumen of the hub, and a needle. The housing may include a tubular portion, which may include two arms coupled thereto. Each of the arms may include a first end coupled to the tubular portion, a second end disposed within the tubular portion, and a bent portion therebetween. The second end of the first arm and the second end of the second arm may form a duckbill valve. A needle may extend through the housing. Withdrawing a sharp distal tip of the needle in a proximal direction beyond the second end of each of the arms may close the duckbill valve and facilitate removal of the housing from the hub. Shielding the sharp distal tip of the needle in this manner may prevent blood spatter and exposure to blood and blood-borne pathogens.

Abstract: Catheters include first and second segments that each include a proximal end and a distal end. A first connector of each catheter includes a first portion connected to the distal end of the first segment and a second portion connected to the proximal end of the second segment. The first portion and the second portion are engaged so that the first portion can rotated relative to the second portion about an axis of the first connector. The first segment and the second segment can bend in multiple planes via a rotation of the first portion relative to the second portion about the axis.

Abstract: A catheter mounting arrangement including a main housing unit configurable to be fastenable around a catheter that has been inserted into a fluid cavity within a patient. The main housing unit includes a slot that defines a longitudinal opening through which an uninserted section of tubing of the inserted catheter is passable there through. The main housing unit and inserted catheter includes an engagement arrangement so that once the uninserted section of the tubing of the inserted catheter has passed through the slot there is a fixed vertical support of the catheter within the main housing unit so that the uninserted section of tubing of the inserted catheter remains substantially upright and/or substantially free of kinks or bends.

Abstract: A medical device includes: an elongated tube having a wall defining a lumen for the elongated tube, wherein the wall of the elongated tube comprises a first opening; and a first actuating element coupled directly or indirectly to the wall of the elongated tube; wherein at least a part of the first actuating element and the first opening of the wall are located at a same longitudinal position with respect to a longitudinal axis of the elongated tube; and wherein the first actuating element is configured to change size to induce stress and/or displacement at the wall of the elongated tube to cause the elongated tube to bend.

Abstract: A securement device 1 for securely attaching tubular articles 2 to surfaces comprising an anchor pad 3 for placing the securement device 1 on the surface, a substantially cylindrical base 4 on the anchor pad 3 and a screw cap 5 rotatably mountable on the base 4 at a screw mounting 6 defined between the base 4 and the screw cap 5 between an article receiving position and an article gripping position in which radial pressure is applied to the article 2 placed in the securement device 1 to securely hold the article 2 without the use of external adhesive fixings and prevent micro-pistoning of the article 2.

Abstract: The designs herein can be for a flexible and kink-resistant catheter with a support tube which can be radially expanded to enable it to be slid over an inner liner on a mandrel during assembly. The designs are flexible enough to allow the catheter to access remote vessel occlusions but also benefit from good compressive and tensile stiffness. The designs can have a laser cut frame with interlocking structure of circumferentially discontinuous rib struts. The discontinuities can be aligned to form at least one continuous axial seam which is separable to allow for the radial expansion during manufacturing. A series of polymeric outer jackets can coat or encapsulate the struts of the frame, giving variable stiffness and preventing disengagement of the interlocking structure while the catheter is pushed through tortuous anatomy.

Abstract: A smoke evacuating tissue guard includes a tubular body defining a longitudinally-extending passageway, a collar coupled to a proximal end portion of the tubular body, and an outlet coupled to the collar and in fluid communication with an annular channel defined through the collar. Upon application of suction through the smoke evacuating tissue guard, the smoke evacuating tissue guard establishes a fluid path extending from the passageway of the tubular body and into the annular channel of the collar via an annular gap defined between the tubular body and the collar.

Abstract: In one embodiment, a filter assembly for use in an insufflation system is described. The filter assembly comprises: a filter medium operative to filter medical gases; a housing comprising an inlet, an outlet and the filter medium, the housing defining a gases flow path through the filter medium between the inlet and the outlet; and at least one heating element being positioned in the housing and being configured to heat the filter medium; and wherein, the at least one heating element is spaced apart from the filter medium and from an inner surface of the housing.

Abstract: An ear irrigation device includes a water reservoir, a water inlet chamber, a water inlet assembly communicating with the water inlet chamber and a water outlet assembly communicating with the water inlet chamber. A piston is inserted at one end of the water inlet chamber, the piston and an interior of the water inlet chamber form a chamber, a recess is formed on a side of the piston away from the chamber, a rotor is rotatably connected in the recess, the rotor is connected with a link, an end of the link away from the rotor is connected with an eccentric rotating assembly, one end of the water inlet assembly communicates with the water reservoir, a check valve is arranged in the water inlet assembly, and another check valve is arranged in the water outlet assembly.

Abstract: A device for conveying a biological material includes a body including an aperture configured to enable connection with an outside of the body and a chamber configured to store a biological material, a plurality of conveyors accommodated in the body and configured to convey the material, and a driver configured to select one of the plurality of conveyors, align the selected conveyor with the aperture, and move the selected conveyor to the outside of the body through the aperture.

Abstract: A needleless injection system includes a pusher that pushes a plunger within a tapered bore of a cartridge. The pusher includes a nib, the tip of which is a ball.

Abstract: An apparatus for rinsing sinuses or eyes, comprising a hand crushable container containing saline solution, and a dispenser configured to make a liquid tight seal with the container at one end, and a liquid tight seal with a nostril or an eye socket at the other end.

Abstract: A disposable medical introduction system including a medical device and a disposable inserter. The disposable inserter includes a carrier to receive the medical device. The carrier includes at least one annular projection. The disposable inserter includes a retractor received within the at least one annular projection and movable relative to the at least one annular projection. The retractor has at least one retaining arm. The disposable inserter includes a needle cartridge coupled to the retractor that includes an insertion needle. The at least one retaining arm cooperates with the needle cartridge to maintain the insertion needle in a first, extended state. A movement of the retractor relative to the at least one annular projection releases the at least one retaining arm to move the insertion needle from the first, extended state to a second, retracted state.

Abstract: An organizing, safety and securement device for use with a peripheral intravenous catheter includes: (a) a catheter base with an opening, that is covered by a transparent membrane, and an upper securement element with a luer fitting indentation, (b) a lower securement element having a top surface with a luer fitting indentation (c) an organizer base with upper and lower clamping members that are hinged together and have free surfaces with tubing indentations that include color coded, mainline and apinch tubing portions, and (d) a tether which connects the catheter and organizer bases.

Abstract: The present embodiments provide strain relief members for a medical device delivery system, methods of use thereof, and methods of manufacturing. In one embodiment a strain relief member may include a support having a first end with a first outer diameter, a second end having a second outer diameter, an inner surface facing a support lumen that extends axially through the support along a longitudinal axis, and an outer surface opposite to the inner surface. An embodiment may also include an overlay coupled to a portion of the outer surface of the support, where the overlay comprises a first material and the support comprises a second material, and the first material is more flexible than the second material. A liner may be disposed in a portion of the support lumen and a first connector disposed over a portion of the support.