Patents Examined by Phuoung Huynh
  • Method of inducing a CTL response
    Patent number: 6994851
    Abstract: A method of inducing a cytotoxic T-lymphocyte (CTL) response to an antigen is disclosed. The method involves delivering the antigen to the lymphatic system of an animal regularly over a sustained period of time using, e.g., an osmotic pump. The method is advantageous over prior art methods for inducing a CTL response in that it does not require repetitive immunizations or the use of adjuvants. The method of the present invention can be used for the induction of CTLs in tumor or infectious disease immunotherapy.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: February 7, 2006
    Assignee: MannKind Corporation
    Inventors: Thomas M. Kundig, John L. Simard