Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing such molecules, and processes of using such molecules and compositions against such pests. These molecules and compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
Type:
Grant
Filed:
January 18, 2017
Date of Patent:
April 3, 2018
Assignee:
Dow AgroSciences LLC
Inventors:
Thomas Barton, Xin Gao, Jim Hunter, Paul R. LePlae, Jr., William C. Lo, Joshodeep Boruwa, Raghuram Tangirala, Gerald B. Watson, John Herbert
Abstract: Provided are substituted heteroaryl aldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
Type:
Grant
Filed:
December 28, 2012
Date of Patent:
April 21, 2015
Assignees:
Global Blood Therapeutics, Inc., Cytokinetics, Inc., The Regents of the University of California
Inventors:
Brian Metcalf, Chihyuan Chuang, Jeffrey Warrington, Kumar Paulvannan, Matthew P. Jacobson, Lan Hua, Bradley Morgan
Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
Type:
Grant
Filed:
November 15, 2012
Date of Patent:
October 21, 2014
Assignee:
Allergan, Inc.
Inventors:
Xialing Guo, Zhen Zhu, Thomas C. Malone, Julie Wurster
Abstract: The invention relates to novel heterocyclic compounds and pharmaceutical preparations thereof. The invention further relates to methods of treatment using the novel heterocyclic compounds of the invention.
Type:
Grant
Filed:
October 10, 2013
Date of Patent:
October 21, 2014
Assignee:
Calithera Biosciences Inc.
Inventors:
Jim Li, Lijing Chen, Bindu Goyal, Guy Laidig, Timothy Friend Stanton, Eric Brian Sjogren