Patents Examined by Ponnathapu Achutamurty
  • Effector proteins of Rapamycin
    Patent number: 6313264
    Abstract: This invention comprises novel Rapamycin-FKBP12 binding proteins of mammalian origin for identification, design and synthesis of immunomodulatory, anti-restenosis or anti-tumor agents, as well as fragments of the proteins and the DNA, cDNA, antisense RNA and DNA segments corresponding to the proteins. This invention also comprises methods for isolating the proteins and therapeutic uses related to the proteins.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 6, 2001
    Assignees: American Home Products Corporation, The Trustees of Columbia University
    Inventors: Thomas J. Caggiano, Yanqiu Chen, Amedeo A. Failli, Katherine L. Molnar-Kimber, Koji Nakanishi