Abstract: Persons having the Factor VLEIDEN mutation and a lower than average plasma level of TFPI have been found to be at elevated risk of thrombosis. Prophylactic methods for reducing the risk of thrombosis employ the administration of TFPI to achieve higher levels in the plasma.
Type:
Grant
Filed:
November 1, 1999
Date of Patent:
June 19, 2001
Assignee:
The University of Vermont and State Agriculture
College
Inventors:
Cornelis Van't Veer, Michael Kalafatis, Kenneth G. Mann