Abstract: Described herein are methods and compositions for inducing melanogenesis in a human subject. The method comprises administering to a subject an alpha-MSH analogue, in an effective amount and time to induce melanogenesis by the melanocytes in epidermal tissue of subject without inducing homologous desensitization of the melanocortin-1 receptors.
Type:
Grant
Filed:
April 21, 2016
Date of Patent:
September 18, 2018
Assignee:
Clinuvel Pharmaceuticals Limited
Inventors:
Michael John Kleinig, Thomas R. Tice, Jay K. Staas