Abstract: The present invention relates to a compound having the general formula (1) wherein in the general formula (1) the residues R1 to R8 and Ar are the same or different and are independently from each other selected from the group consisting of hydrogen, unsubstituted hydrocarbon groups, substituted hydrocarbon groups and inorganic groups, wherein at least one of the residues R1 to R8 and Ar is a hydrophilic group, such as for instance a group comprising one or more polyethylene groups.
Type:
Grant
Filed:
September 30, 2019
Date of Patent:
April 16, 2024
Assignee:
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
Inventors:
Qiang Chen, Akimitsu Narita, Klaus Müllen, Sapun Parekh, Mischa Bonn, Xiaomin Liu
Abstract: Provided include methods, compositions and kits for treating cancer in a subject. The method can comprise administrating an FGFR inhibitor (for example, AZD4547) and a PLK1 inhibitor (for example, onvansertib) to the subject in a manner sufficient to inhibit progression of the cancer.
Type:
Grant
Filed:
October 14, 2022
Date of Patent:
April 16, 2024
Assignee:
Cardiff Oncology, Inc.
Inventors:
Maya Ridinger, Mark Erlander, Anju Karki