Patents Examined by Rachel B. Kapust
  • Antibodies to protein HPMBQ91
    Patent number: 6919433
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: July 19, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Yi Li, Zhizhen Zeng, Hla Kyaw, Carrie L. Fischer, Haodong Li, Daniel R. Soppet, Reiner L. Gentz, Ying-Fei Wei, Paul A. Moore, Paul E. Young, John M. Greene, Ann M. Ferrie, Gregg A. Hastings
  • Variant TLR4 nucleic acid and uses thereof
    Patent number: 6740487
    Abstract: The invention provides methods to identify polymorphisms at the human TLR4 locus, as well as methods to identify individuals at risk of indications that increase their morbidity and mortality.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: May 25, 2004
    Assignee: University of Iowa Research Foundation
    Inventors: David A. Schwartz, Brian C. Schutte