Abstract: A porous textile product made from bioactive glass fibers. The fibers in the product are of at least two types, fiber A and fiber B, with fiber A being made from a bioactive glass, and fiber B being made from a weakly bioactive glass.
Type:
Grant
Filed:
June 7, 2001
Date of Patent:
February 11, 2003
Inventors:
Heimo Ylänen, Hannu Aro, Kaj Karlsson, Antti Yli-Urpo, Mikko Hupa, Egon Nordström
Abstract: Compositions and methods for treating nails and adjacent tissues are disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with therapeutic agents, hydrophilic polymers, and other optional components. The compositions optionally include an appropriate aqueous carrier for topical administration. The methods involve applying an effective nail-enhancing amount of the composition to the nails and adjacent tissues for a sufficient amount of time to cause the formation of a hydroxyapatite or other calcium phosphate mineral layer on the nail surface.
Type:
Grant
Filed:
January 19, 2000
Date of Patent:
February 11, 2003
Assignee:
USBiomaterials Corporation
Inventors:
Guy LaTorre, David C. Greenspan, Alice D. Greenspan
Abstract: An embodiment of the present invention is a cosmetic composition with enhanced gloss properties. The cosmetic compositions of the present invention contain at least one film former with high gloss properties, i.e., a glossy film former having a gloss effect measurement of greater than 50%, at least one thickener, and at least one wax. The combination of the thickener and the wax are present in a combined amount such that the gloss effect measurement of the composition is greater than 50%. The glossy cosmetic composition may be a mascara, eyeliner, lip gloss, or blush.
Abstract: This invention concerns wettable microcapsules ethylcellulose coated cores and to processes for their preparation; in particular, to microcapsules with ethylcellulose coats that are wettable so that they are suspendable in aqueous medium. The wettable microcapsules can be prepared by applying ethylcellulose onto drug containing core by phase separation from a solvent to provide microcapsules, optionally washing said microcapsules with a solvent in which said microcapsules are substantially insoluble and drying, (a) one or more surfactants is/are incorporated in the solvent at the phase separation step; and/or (b) one or more surfactants is/are incorporated in the solvent used to wash the microcapsules; and/or said microcapsules being coated with one or more surfactants optionally in the presence of a binder.
Type:
Grant
Filed:
October 10, 2000
Date of Patent:
January 21, 2003
Assignee:
Eurand International S.p.A.
Inventors:
Massimo Maria Calanchi, Stefano De Luigi Bruschi, Leonardo Gentilini, Luigi Giovanni Mapelli
Abstract: A hair coloring composition suitable for application to hair by containing one or more hair substantive direct dyes, in a controlled evaporation rate vehicle, and on an optional polymeric ruboff shield, and a controlled viscosity to be reasonably free flowing yet not drip or cause build-up on the hair.
Abstract: Described is a permanently and continuously fragrance-emitting dry or wet wipe laminar fabric article comprising a non-woven fabric lamina having woven therethrough and substantially throughout at least a major portion of the lamina surface at least one continuous fragrance-containing thermoplastic, substantially water-insoluble fiber, which controllably and continuously releases fragrance at least for the time period during which the fabric article is in use. Such fragrance may also have antimicrobial properties. Optionally, one or more antimicrobial substances may also be releasably contained in the fiber containing the fragrance or in a fiber apart therefrom. The fabric article optionally contains additional fragrance and/or antimicrobial agent absorbed in or adsorbed on the non-woven fabric lamina.
Type:
Grant
Filed:
December 21, 1999
Date of Patent:
December 31, 2002
Assignee:
International Flavors & Fragrances Inc.
Inventors:
Dionisio Ferenc, Marcos Angelini, Elena Susana Novas, Leonardo Oscar D'Ascanio
Abstract: The invention concerns a hairstyling composition, in a cosmetically acceptable medium: (1) at least a polymer (A) selected such that the film obtained by drying a mixture of said polymer (A) with ethanol or water, at room temperature and a relative moisture content of 50%, has a mechanical profile defined by at least (i) an ultimate elongation rate (&egr;r) not less than 300%; (ii) a creep at 300 seconds (R300) not less than 45%; and (iii) when the creep at 300 seconds ranges between 45 and 60% the elongation is less than 1300%; (2) at least a non-ionic film forming polymer (B), different from polymer (A). The invention also concerns a hairstyling of hair-fixing method using said composition and its use for formulating hairstyling products such as lacquers, sprays or foams, for hairstyling or hair-fixing.
Abstract: A highly storage-stable composition for vaginal administration of clindamycin is disclosed which is useful for the treatment of bacterial vaginosis. The composition is a vaginal suppository containing an antimicrobially effective amount of clindamycin dispersed in a Hard Fat NF suppository base. Hard Fat NF suppository bases provide a clindamycin product having long term storage stability while providing efficacy against bacterial vaginosis which is equivalent to clindamycin vaginal creams.
Type:
Grant
Filed:
July 20, 2000
Date of Patent:
December 17, 2002
Assignee:
Pharmacia & Upjohn Company
Inventors:
Lorraine Elisabeth Pena, Phil Bryan Bowman, Robert Shih-Liang Chao, Carolyn V. Pesheck
Abstract: Injectable compositions having improved injectability. The injectable compositions include microparticles suspended in an aqueous injection vehicle having a viscosity of at least 20 cp at 20° C. The increased viscosity of the injection vehicle that constitutes the fluid phase of the suspension significantly reduces in vivo injectability failures. The injectable compositions can be made by mixing dry microparticles with an aqueous injection vehicle to form a suspension, and then mixing the suspension with a viscosity enhancing agent to increase the viscosity of the fluid phase of the suspension to the desired level for improved injectability.
Type:
Grant
Filed:
May 25, 2000
Date of Patent:
December 17, 2002
Assignee:
Alkermes Controlled Therapeutics, Inc. I
Inventors:
J. Michael Ramstack, M. Gary I. Riley, Stephen E. Zale, Joyce M. Hotz, Olufunmi L. Johnson
Abstract: This invention is to provide an agent for therapy and prevention of allergic diseases which has no adverse action, shows a high safety even by administration for a long period and is able to be utilized to food and/or beverage, cosmetics, etc. which are used daily. To be specific, it provides antiallergic agent and anti-inflammatory agent characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient; a method for the addition of an antiallergic agent for oral administration or an anti-inflammatory agent for oral administration which is characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient to food and/or beverage for prevention, suppression and mitigation of allergic symptoms or inflammatory symptoms.
Type:
Grant
Filed:
February 8, 2001
Date of Patent:
December 10, 2002
Assignee:
National Agricultural Research Organization
Inventors:
Kenkou Tsuji, Mari Yamamoto, Keiko Kawamoto, Hirofumi Tachibana
Abstract: The present invention relates to novel, orally administered compositions comprising two redox systems: reduced ascorbic acid in a sustained release form and oxidized isoquercetin with an increased concentration of reduced vitamin C over a prolonged time in the brain. These compositions are useful as neuroprotective agents possessing preventive properties against memory dysfunctions.
Abstract: Methods and compositions are disclosed for providing prolonged-release of therapeutic agents by way of in situ stereotaxic implantation in specific loci, including pathways, to treat known disorders. One or more microstructures comprising therapeutic agents and pharmaceutically acceptable carriers are implanted, for example, through a cannula. The microstructures are of a sufficient size and shape to prevent dispersion from the implant site.
Type:
Grant
Filed:
July 2, 2001
Date of Patent:
December 10, 2002
Assignee:
Advanced Research and Technology Institute, Inc.
Abstract: The present invention relates to a disposable cleansing article comprising:
a) a water insoluble substrate comprising:
1) an apertured first layer wherein said first layer has a water flux rate of from about 0.4 cm3/cm2-s to about 20 cm3/cm2-s;
2) a second layer attached to said first layer; and
b) a cleansing component comprising a surfactant, said component being disposed adjacent to the substrate.
The present invention also relates to a method of cleansing the skin and hair which comprise the steps of:
a) wetting with water a disposable cleansing article comprising a water insoluble substrate comprising:
1) an apertured first layer having a water flux rate of from about 0.4 cm3/cm2-s to about 20 cm3/cm2-s; and
2) a second layer attached to said first layer;
and a cleansing component comprising one or more surfactants said component being disposed adjacent to the substrate; and
b) contacting the skin or hair with the wetted article.
Abstract: A composite thermoset polymer matrix structure having a plurality of homogeneously bonded thermoset polymer layers and a method of forming the same is disclosed. Each of the layers is formed from either a pure thermoset polymer resin or a composition of any of a variety of thermoset polymer resins and any of a variety of agents or combination of agents heterogeneously dispersed and suspended within the thermoset polymer resin. In this manner, each layer exhibits a distinct desirable functional property or characteristic depending upon an intended application. The agents are selected from a group of additives including but not limited to anti-microbial agents, anti-fungal agents, anti-viral agents, anti-thrombotic agents, friction reducing agents; radiopaque agents, and electrically conductive or resistive agents. The composite thermoset polymer matrix structure may be formed into any size or any shape, object, or structure.
Type:
Grant
Filed:
September 21, 1999
Date of Patent:
November 26, 2002
Assignee:
Phelps Dodge High Performance Conductors of SC & GA,
Inc.
Abstract: A single serving paraffin treatment system and method of application is disclosed which includes the steps of heating a small quantity of paraffin above its melting temperature, applying the paraffin to the hand or foot with a brush. The paraffin is contained in individualized disposable containers which are receivable in a heating unit. The heating unit preferably has at least two temperature settings.
Type:
Grant
Filed:
November 8, 2000
Date of Patent:
November 26, 2002
Assignee:
E.O.H. Industries, Inc.
Inventors:
Beth Ann Barrick Hickey, Rebecca Phillips Gentry, Royce E. Gentry
Abstract: A method for reducing certain effects associated with a negative calorie balance in a human includes the step of administering conjugated linoleic acid to a human in an amount effective to reduce at least one of the effects.
Type:
Grant
Filed:
April 4, 2000
Date of Patent:
November 19, 2002
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Michael W. Pariza, Richard L. Atkinson, Jr.
Abstract: The invention provides a method for combating and preventing nosocomial infections, comprising providing to health care facilities textile fabrics incorporating fibers coated with an oxidant, cationic form of copper, for use in patient contact and care, wherein the textile fabric is effective for the inactivation of antibiotic resistant strains of bacteria.
Abstract: Biodegradeable polymer compositions suitable for intraperitoneal administration to treat a mammalian subject having ovarian cancer are described, wherein the polymer compositions provide extended release of the antineoplastic agent into the peritoneum of the subject. The subject compositions can increase the median survival rate from the cancer by at least about 10%, as compared with the median survival rate obtained by administration of a composition comprising the same dosage of the antineoplastic agent without the biodegradeable polymer. Solid articles and methods for treating ovarian cancer are also described.
Abstract: Disclosed are kits of parts comprising a first container comprising a cyanoacrylate composition and a second container comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. Mixture of these compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film on mammalian skin.
Type:
Grant
Filed:
June 1, 2000
Date of Patent:
November 5, 2002
Assignee:
Flowers Park Ltd.
Inventors:
Connie C. Lee, Richard J. Greff, Ian N. Askill
Abstract: The present invention relates to substantially uniform, discontinuous films of a topical product having a defined abrasion resistance, coverage value and particle spacing. The films are wear or transfer resistant and provide good skin coverage, while simultaneously providing improved skin appearance, e.g., good apparent coverage and a natural look. The films can be formed by methods which provide the defined particle coverage and spacing, including silk screening and the like and electrostatic spray techniques. The films are preferably formed by electrostatically spraying the composition onto the skin.