Abstract: A needle and suture assembly is provided for use with an endoscopic suturing device with a needle holder arm. The needle assembly includes a needle tip and a needle body. The needle tip has a sharp end, a capture groove, a tab groove and a plug portion positioned between the capture groove and the tab groove. The needle body has first and second ends, tip tabs, retainers for removably retaining the needle body relative to the needle holder arm, and a suture opening. The needle tip is fixed relative to the needle body by plastic deformation of the tip tabs into the tab groove. A suture extends into the suture opening of the needle body and is fixed therein.

Abstract: Disclosed are implantable medical devices for the occlusion of a bodily lumen, cavity, vessel, or organ, as well as methods for manufacturing such occlusion devices, and methods for treating a subject using the occlusion devices. The devices generally include a wire having shape memory properties and a flexible membranous material disposed about the wire. Some embodiments include a lateral fringe on the membranous material. Some embodiments include a fluid capture cup affixed to the wire.

Abstract: A tissue specimen retrieval bag assembly includes a tissue specimen bag having an open proximal end and a closed distal end, the proximal end including a cuff defined therein and extending therearound. A flexible bag brim is disposed within the cuff, the flexible bag brim transitionable between a first, collapsed configuration and a second, expanded configuration. The flexible bag brim includes a D-Shaped cross section configured to facilitate both furling the tissue specimen bag onto itself around the bag brim when the bag brim is disposed in the second, expanded configuration and securing the tissue specimen bag in a desired furled configuration. The flexible bag brim defines a cavity therein configured to facilitate compression thereof and to facilitate handling of the bag brim by a surgical instrument.

Abstract: The present disclosure is directed to a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method may include providing an intravascular device having a distal portion and a longitudinal axis and inserting the intravascular device into the vascular lumen. The method may further include positioning the distal portion in the vascular wall, rotating the intravascular device about the longitudinal axis, and advancing the intravascular device within the vascular wall.

Abstract: Provided herein are vitrectomy instruments and related systems and methods in which the vitrectomy instruments may include a forward needle stop and a cutter stop to reduce dimensional variation of a cutter of the vitrectomy instruments, allowing for a location of the port formed in a needle of the cutter to be positioned closer to a distal tip of the cutter. With the port located closer to a distal end of the cutter, the port is able to be positioned closer to the retina of an eye.

Abstract: A surgical device is provided.

Abstract: A forceps includes a drive assembly and an end effector assembly having first and second jaw members movable between a spaced-apart position, a first approximated position, and a second approximated position. The drive assembly includes a drive housing and a drive bar. The proximal end of the drive bar is coupled to the drive housing, while the distal end of the drive bar is coupled to at least one of the jaw members. The drive housing and the drive bar are selectively movable in conjunction with one another between a first position and a second position to move the jaw members between the spaced-apart position and the first approximated position. The drive assembly is selectively activatable to move the drive bar independent of the drive housing from the second position to a third position to move the jaw members from the first approximated position to the second approximated position.

Abstract: An apparatus for use in tissue removal from a body organ is presented. The apparatus comprises a hand-held probe device, a rotating motor device and a connection assembly configured for removably interconnecting between the hand-held probe device and the rotating motor device. The hand-held probe device is disposable and comprises a housing having proximal and distal ends, a rotatable cutting tool extending distally from the distal end of the housing and being configured for cutting and removing tissue during rotation, and a transmission assembly passing inside the housing between the proximal and distal ends and being configured for transmitting rotational power to the rotatable cutting tool. The connection assembly is configured for engaging between the rotating motor device and the transmission assembly to thereby controllably rotate the cutting tool and remove tissue.

Abstract: A soft suture anchor construct is provided for placement in or against tissue or bone. The anchor includes an all-suture anchor having two ends positioned in a first direction in a pre-deployment configuration. In a deployed configuration, the two ends are positioned in a second direction different from the first direction. The suture anchor construct also includes a filament passing through the anchor at a plurality of passing locations, where the filament changes direction at least once along the direction of the longitudinal axis of the anchor and forms at least one slack line. In the pre-deployment configuration, the filament extends a first length between adjacent passing locations, and in the deployed configuration, the filament extends a second length between adjacent passing locations. The second length is shorter than the first length. The suture anchor construct may be deployed in a bone hole with an inserter, anchor driver, or other deployment device.

Abstract: The present invention relates to a device for fracturing and removing ocular lenses. The device mainly comprises a rotational screw drill, a sleeve and a hydraulic suction system. The rotational screw drill has reversed conical propellers which help to grind the particles. The rotational screw drill is housed in a sleeve, which comprises a rigid cylinder and a suction cup. The suction cup has a bell or funnel shape with an elliptical cross-section. Finally, the hydraulic suction system is key for the present invention performance. Also, the invention relates to a method comprising the steps of breaking, splitting the cataract or lens tissue and simultaneously or subsequently grinding the particles inside the sleeve by means of the rotational screw drill and the sleeve, and finally removing them from the medium via the sleeve by means of a hydraulic suction system.

Abstract: A catheter placing instrument is provided. The catheter placing instrument includes an elongated body that extends in a longitudinal direction from a proximal end to a distal end. The elongated body has a top surface configured to receive a catheter extending from the proximal end to the distal end. The elongated body includes a catheter insertion section and a grip section. The catheter insertion section includes a catheter locking clamp located at the distal end of the elongated body, and the grip section includes a catheter guide. The catheter placing instrument can be used to place or implant any tubular medical device within a patient's body. A method of placing a tubular medical device at a deep location within a patient's body is also provided.

Abstract: An atherectomy catheter includes an elongate catheter body, a cutter at a distal end of the catheter body, and a nosecone attached to a distal end of the catheter body. The cutter is configured to excise tissue from the body. The nosecone is configured to hold tissue excised from the cutter. The nosecone includes a distal section, a proximal section, and a connection mechanism that is configured to allow the distal section to attach and detach from the proximal section during use. The distal section includes a plug configured to sit within an inner diameter of the proximal section when the proximal section is connected to the distal section.

Abstract: A medical device for crushing an object in a body lumen, the medical device including: an elongated shaft portion rotatably driven; a crushing unit provided with bendable wire rods and rotatable together with the shaft portion; and a sliding unit fixed to each of end portion of the wire rods on at least one of a distal side of and a proximal side of the wire rods and is interlocked with the shaft portion so as to be slidable in an axial direction of the shaft portion. The shaft portion is provided with contact portions that come into contact with the sliding unit during rotation and limit relative rotation of the shaft portion and the sliding unit. After the sliding unit is attached to the contact portions, the sliding unit rotates in the same direction as the shaft portion along with the rotation of the shaft portion.

Abstract: The present invention related to a coring tool for preparing a core or opening through tissue and methods of use thereof.

Abstract: A system for accessing a central pulmonary artery includes an elongate, flexible tubular catheter, having a proximal end, a distal end and a catheter hub on the proximal end. An elongate, flexible rail has a proximal end, a distal end and a rail hub on the proximal end. The rail has a distal advance segment which extends at least about 10 cm beyond the distal end of the catheter when the catheter hub is adjacent the rail hub.

Abstract: Systems and methods for delivering and implanting heart valves are disclosed. The delivery systems can include an integrated introducer. The integrated introducer can include a sheath having an inner diameter that is smaller than the outer diameter of a delivery capsule of the delivery system and an outer diameter that is approximately equal to the outer diameter of the delivery capsule. The integrated introducer can include a hub having a hemostatic seal. The hub can have a locking mechanism configured to fix the integrated introducer in place on the delivery system.

Abstract: A surgical portal apparatus includes a sleeve having a proximal end and a distal end that extends along a longitudinal axis, and a surgical tape. The sleeve includes an inner wall defining an internal longitudinal passageway dimensioned for permitting passage of a surgical object therethrough and an outer wall configured for positioning against tissue. The inner and outer walls define at least a partial annular space therebetween, the annular space being in fluid communication with an opening in the outer wall. The surgical tape includes a body portion retained within the annular space of the sleeve and a leading tab extendable through the opening in the outer wall of the sleeve. The surgical tape has a first surface and a second surface, each of the first and second surfaces having at least one of tissue reactive functional groups and self-reactive functional groups.

Abstract: Balloon catheter devoid of guidewire or guidewire lumen and having a proximal shaft with only a single continuous lumen. A coil assembly is mounted at its proximal end to the distal end of the proximal shaft defining an interface therebetween. Disposed about a distal section of the proximal shaft and a proximal section of the coil assembly is a sleeve. A balloon, having a vent hole, forms a proximal leg seal about an outer surface of a distal end of the sleeve and an opposite distal leg seal. The sleeve covers the interface and extends axially in a distal direction terminating underneath the proximal leg seal of the balloon. A distal section of the coil assembly at least partially coincides with the distal leg seal of the balloon. A wire member secured at a plurality of connection points along the coil assembly extends axially within the balloon.

Abstract: An exemplary valve repair device is released from tissue of a valve of a patient by applying tension to a movable arm of a clasp in a retraction direction. A fixed arm of the clasp is attached to an inner paddle portion of a paddle of the valve repair device. The inner paddle portion is connected to an outer paddle portion of the paddle of the valve repair device. Pulling the moveable arm of the clasp flexes the inner paddle portion to allow the moveable arm to move in the retraction direction and thereby release the clasp from the valve tissue.

Abstract: In a treatment instrument, a shaft is rotatable around a predetermined rotation axis relative to the housing, and an end effector is bendably or curvably attached to the shaft. In the treatment instrument, an interlocking member is provided independently of the shaft, and a receiver is provided in such a manner that rotation of the receiver relative to the housing is restricted or that rotation of the receiver relative to the shaft is restricted. The interlocking member moves in conjunction with bending or curving movement of the end effector so that the receiver engages with the interlocking member, thereby preventing rotation of the shaft around the predetermined rotation axis.