Patents Examined by Rao M. Uppu
  • Compounds
    Patent number: 6342601
    Abstract: The invention provides certain pyrrolo-, thieno-, furano- and pyrazolo-[3,4-d]pyridazinones, processes for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and methods of treatment involving their use.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: January 29, 2002
    Assignee: AstraZeneca AB
    Inventors: John Bantick, Martin Cooper, Philip Thorne, Matthew Perry
  • Triazolo-pyridazine derivatives as ligands for GABA receptors
    Patent number: 6291460
    Abstract: 1,2,4-triazolo[4,3-b]pyridazine derivatives, represented by wherein Z represents cyclobutyl, 1-methylcyclopentyl or pyrrolidin-1-yl, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, are useful in the treatment of anxiety and convulsions.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: September 18, 2001
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Timothy Harrison, Timothy Jason Sparey, Martin Richard Teall