Patents Examined by Raymond J. Henley, III
  • Patent number: 10383852
    Abstract: The present invention targets the Zika virus and other disease-causing microbes including viruses, bacteria, fungi, and parasites. It does this using agents and methods with little toxicity compared to existing therapies.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: August 20, 2019
    Inventor: Steven Baranowitz
  • Patent number: 10376527
    Abstract: The present invention relates to a stable oral liquid pharmaceutical composition of celecoxib or its pharmaceutically acceptable salts thereof. The celecoxib present in the compositions as described herein do not show any precipitation when subjected in Fasted-State Simulated Gastric Fluid (FaSSGF) at pH 2.0, temperature of 37° C.±0.5° C. and under stirring at a speed of 50 rpm at least for 60 minutes. It also relates to the process of preparing and method of using said composition of celecoxib.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: August 13, 2019
    Assignee: DR. REDDY'S LABORATORIES LTD.
    Inventors: Ankit Baheti, Bijay Kumar Padhi, Supritha Vakada, Rajeev Singh Raghuvanshi
  • Patent number: 10369128
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a cis-diamine platinum(II) thione complex. A cis-diamine platinum(II) thione complex and compositions containing it.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: August 6, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohammed Yagoub Jomaa, Anvarhusein A. Isab
  • Patent number: 10357473
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a cis-diamine platinum(II) thione complex. A cis-diamine platinum(II) thione complex and compositions containing it.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: July 23, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohammed Yagoub Jomaa, Anvarhusein A. Isab
  • Patent number: 10350182
    Abstract: The present invention relates to methods of treating overactive bladder and the symptoms associated therewith, for example, urinary urgency, frequency of micturitions, nocturia, and urgency urinary incontinence. One treatment method according to the present invention comprises treatment with the beta-3 adrenergic receptor agonist solabegron. Another treatment combination according to the invention comprises solabegron, and a muscarinic receptor antagonist which results in a synergistic effect on the symptoms associated with OAB.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: July 16, 2019
    Assignee: VELICEPT THERAPEUTICS, INC.
    Inventors: Stephen Caltabiano, Eliot Ohlstein, Stewart McCallum
  • Patent number: 10350187
    Abstract: The present disclosure relates to methods and compositions for suppressing pathogenic bacterial growth, fungal growth, or microbial growth in or on a selected area of skin or open wound. An area of the skin or open wound having pathogenic bacterial growth, fungal growth, or microbial growth is selected for the suppression of the growth. A suppressing material comprising punicic acid is applied to the selected area of the skin and the pathogenic bacterial growth, fungal growth, or microbial growth is suppressed. Methods of making and using the suppressing material comprising punicic acid are also presently provided.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: July 16, 2019
    Inventor: David Changaris
  • Patent number: 10335387
    Abstract: A method for treating an infectious disease, including the step of administering an isothiocyanate functional surfactant to a patient having an infectious disease.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: July 2, 2019
    Assignee: The William M. Yarbrough Foundation
    Inventor: Michael E. Silver
  • Patent number: 10335375
    Abstract: Described herein are abuse deterrent oral pharmaceutical compositions, methods for making the same, and methods of treatment using such compositions. In particular, oral pharmaceutical compositions that mitigate the risk of overingestion of one or more active pharmaceutical ingredients are described.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: July 2, 2019
    Assignee: Patheon Softgels, Inc.
    Inventors: Justin Hughey, Jason Vaughn
  • Patent number: 10328044
    Abstract: The invention features a pharmaceutical suspension containing drug particles, a drug delivery device anchored in the mouth for continuously administering the pharmaceutical suspension, and methods of their use.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: June 25, 2019
    Assignee: SynAgile Corporation
    Inventor: Adam Heller
  • Patent number: 10328154
    Abstract: A topical composition and methods of making the composition is disclosed. The composition may comprise an ointment base, C11-C40 alcohols or acids, and a polymer. The ointment base may be in an amount of at least about 50% of the topical composition by weight. The polymer may be substantially soluble in the ointment base.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: June 25, 2019
    Assignee: BUFFERAD Illinois Inc.
    Inventors: Xiaoyan Xu, Wen Yang, Nguyet Le, Jerry Z. Zhang
  • Patent number: 10322095
    Abstract: Disclosed are methods and topical formulations for treating and/or preventing cell proliferative diseases and disorders including breast cancer and ductal carcinoma is situ (DCIS) using local transdermal therapy (LTT). The disclosed methods typically include administering topically to the breast or breasts of the patient a topical formulation comprising an effective dose of the tamoxifen metabolite, N-desmethyl-4-hydroxytamoxifen (i.e., endoxifen or ENX) for treating breast cancer. The topical formulation may be described as a transdermal formulation and the topical formulation may comprise, consist essentially of, or consist of endoxifen as an active ingredient.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: June 18, 2019
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Seema Ahsan Khan, Oukseub Lee
  • Patent number: 10322209
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: June 18, 2019
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd Boyce, Lawrence A. Shimp
  • Patent number: 10307432
    Abstract: The present invention relates to stable pharmaceutical compositions of fosaprepitant or a salt thereof in the form of ready-to-use or ready-to-dilute compositions suitable for parenteral administration.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: June 4, 2019
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Sarabjit Singh, Abhijit Jadhav
  • Patent number: 10307392
    Abstract: The disclosed invention generally relates to treatment and/or prevention of symptoms associated with cannabinoid responsive diseases and disorders in subjects in need thereof, as well as the method of administering therapeutically-effective amount of a pharmaceutical compound containing cannabinoids. The disclosed invention further relates to pharmaceutical compounds for treating and/or preventing symptoms associated with said diseases and disorders.
    Type: Grant
    Filed: October 21, 2017
    Date of Patent: June 4, 2019
    Inventor: Alexander Kariman
  • Patent number: 10300033
    Abstract: The invention features a pharmaceutical suspension containing drug particles, a drug delivery device anchored in the mouth for continuously administering the pharmaceutical suspension, and methods of their use.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: May 28, 2019
    Assignee: SynAgile Corporation
    Inventor: Adam Heller
  • Patent number: 10300077
    Abstract: The present disclosure is directed to methods, compositions, and kits for treating dementia.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: May 28, 2019
    Inventor: Steven Hoffman
  • Patent number: 10292972
    Abstract: A pharmaceutical composition containing an anticancer compound, named isopicrinine, isolated from the plant Rhazya Stricta. The pharmaceutical composition may contain a salt, an analog, a derivative, and/or the prodrug of isopicrinine. A method of treating cancer with the pharmaceutical composition is disclosed. A method of extracting isopicrinine is also disclosed.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: May 21, 2019
    Assignee: King Abdulaziz University
    Inventors: Jamal Sabir M. Sabir, Abdullah Y. Obaid, Nahid H. Hajrah, Waseem Mohammed, Zainab H. Abdul-Hameed, Walied M. Alarif, Roop Singh Bora, Seif-Eldin N. Ayyad, Nouf Saeed A. Al-Abbas, Abdulkader M. Shaikh Omer, Mohammed Zainy Mutawakil, Neil Hall, Kulvinder Singh Saini
  • Patent number: 10278389
    Abstract: This disclosure relates to a method for the control or repellency of biting arthropods. The method comprises bringing the biting arthropods into contact with a biting arthropod repellent formulation. The biting arthropod repellent formulation comprises an alkoxy nootkatol separate from, or in combination, or in synergistic combination, with skin or plant derived compounds and compounds structurally similar to them (e.g., ketones, cyclic ketones, esters, gamma or delta lactones, and branched and/or unsaturated carboxylic acids), and/or one or more repellents selected from the group consisting of DEET®, para-menthane-3,8-diol (PMD), Picaridin, ethyl 3-[acetyl(butyl)amino]propanoate (IR3535), and other nitrogen-containing repellents including amines, amides, and nitrogen-containing heterocyclic compounds.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: May 7, 2019
    Assignee: Bedoukian Research, Inc.
    Inventors: Robert H. Bedoukian, Patrick Murray Foley
  • Patent number: 10278944
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a cis-diamine platinum(II) thione complex. A cis-diamine platinum(II) thione complex and compositions containing it.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: May 7, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohammed Yagoub Jomaa, Anvarhusein A. Isab
  • Patent number: 10258617
    Abstract: A dose regimes comprising the simultaneous administration of two pharmaceutical compositions, wherein the first pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof for once daily oral administration, and the second pharmaceutical composition is a composition comprising vortioxetine or a pharmaceutically acceptable salt thereof which together with said first composition quickly achieves a steady-state plasma level of vortioxetine in said patient which steady-state plasma level is the same as the steady-state vortioxetine plasma level achieved by the administration to said patient of said first composition alone.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: April 16, 2019
    Assignee: H. Lundbeck A/S
    Inventors: Connie Sanchez Morillo, Karina Krøjer Søby, Benny Bang-Andersen