Patents Examined by Rebecca L. Thompson
  • Patent number: 4734370
    Abstract: A strain of Actinomadura sp., NRRL 15758, is capable of producing the CL-1724 complex of antibiotic substances in isolable quantities under conditions of aerobic fermentation in a culture medium containing assimilable sources of carbon and nitrogen.
    Type: Grant
    Filed: July 1, 1985
    Date of Patent: March 29, 1988
    Assignee: Warner-Lambert Company
    Inventor: Josefino B. Tunac
  • Patent number: 4654306
    Abstract: A novel species of acetic acid bacteria belonging to the genus of Acetobacter, to which a scientific name of Acetobacter altoacetigenes MH-24 (FERM BP-491) is given. The bacteria can grow in a culture medium containing at least 4 w/v % of acetic acid with a pH of 3.5 at the highest. Pure samples of species have been isolated and used for the fermentation production of vinegar without undertaking the conventional inoculation process using the prior art seed vinegar to provide a high-quality vinegar of high acetic acid concentration such as white vinegar, with high production efficiency.
    Type: Grant
    Filed: February 21, 1985
    Date of Patent: March 31, 1987
    Assignee: Nakano Vinegar Co., Ltd.
    Inventors: Etsuzo Entani, Seiichi Fujiyama, Shoji Ohmori, Hiroshi Masai
  • Patent number: 4634667
    Abstract: Process for preparing a heteropolysaccharide from strain NCIB 11883 and use of the latter e.g. as viscosity modifier in an aqueous system such as completion fluids, work over fluids, stimulation fluids, and preferably in drilling fluids and use in connection with well-treatments, and enhanced oil recovery.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: January 6, 1987
    Assignee: Shell Oil Company
    Inventors: John D. Linton, Michael W. Evans, Andrew R. Godley
  • Patent number: 4623624
    Abstract: Highly active pancreatin is obtained by autolysis of an aqueous isopropanol-containing tissue slurry, preferably buffered with sodium bicarbonate, until a test precipitation with aqueous isopropyl alcohol proves positive, and precipitating the batch with a higher concentration of isopropyl alcohol, resulting in a fiber suspension which can be sieved so that the solution obtained permits direct isolation of pancreatin by further increasing the concentration of isopropyl alcohol. A high bulk density of the finished dry preparation is achieved by stirring the precipitated pancreatin with isopropyl alcohol or acetone so as to bring the pancreatin to a concentration of 70-85% of isopropanol or 80-95% of acetone, isolating the pancreatin by suction filtration or centrifuging and drying it by treatment with dry air or nitrogen.
    Type: Grant
    Filed: December 23, 1983
    Date of Patent: November 18, 1986
    Assignee: BASF Aktiengesellschaft
    Inventor: Hans Schultze
  • Patent number: 4612285
    Abstract: A novel antibiotic, awamycin, and its production. Awamycin is active against gram positive bacteria and exhibits growth inhibitory activity against Erhlich ascites and Sarcoma 180 cells. Some of the identifying characteristics of awamycin include a molecular weight of 744.+-.1 (mass spectrum analysis), an elementary analysis of 59.16% C, 6.48% H and 1.88% N; a melting point of 158.degree. C.; an optical rotation of [.alpha.].sub.D 24=+836.degree.. Awamycin is an acidic substance, which provides an orange colored powder, and is poorly soluble in water.
    Type: Grant
    Filed: October 25, 1983
    Date of Patent: September 16, 1986
    Assignee: Kitasato Institute
    Inventors: Iwao Umezawa, Kanki Komiyama
  • Patent number: 4608343
    Abstract: This disclosure describes four new antibacterial agents designated LL-C08078.alpha..sub.1, LL-C08078.alpha..sub.2, LL-C08078.alpha..sub.3 and LL-C08078.beta. produced in a microbiological fermentation under controlled conditions using a new strain of a new species of the genus Streptomyces called Streptomyces majorciensis Labeda, sp. nov., and mutants thereof. These new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found. In addition, these agents are active as growth promotants in warm-blooded animals.
    Type: Grant
    Filed: May 30, 1985
    Date of Patent: August 26, 1986
    Assignee: American Cyanamid Company
    Inventors: David P. Labeda, Joseph J. Goodman, Donald B. Borders, Raymond T. Testa, John H. E. J. Martin, deceased
  • Patent number: 4604352
    Abstract: Starch is converted directly to ethanol by growing a co-culture of Clostridium thermosulfurogenes and Clostridium thermohydrosulfuricum under anaerobic conditions on a starch containing substrate in a medium comprising essential vitamins, minerals and growth factors. The co-culture also produces the thermostable enzymes .beta.-amylase, glucoamylase and pullulanase.
    Type: Grant
    Filed: September 18, 1984
    Date of Patent: August 5, 1986
    Assignee: Michigan Biotechnology Institute
    Inventors: Joseph G. Zeikus, Hyung-Hwan Hyun
  • Patent number: 4603110
    Abstract: Starch hydrolyzates having a dextrose equivalent value of not more than about 25 which contain up to about 20% glucose by weight and up to about 40% maltose by weight, with the combination of glucose and maltose not exceeding about 40% by weight of the composition.
    Type: Grant
    Filed: October 21, 1983
    Date of Patent: July 29, 1986
    Assignee: Grain Processing Corporation
    Inventors: Alpha L. Morehouse, Pamela A. Sander
  • Patent number: 4591559
    Abstract: The present invention relates to a novel polyether ionophore antibiotic of the formula ##STR1## and its pharmaceutically acceptable salts. The compound of formula I and its salts exhibit activity as an antibacterial agent and as an anticoccidial agent.
    Type: Grant
    Filed: January 22, 1985
    Date of Patent: May 27, 1986
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Chao-Min Liu, John Westley
  • Patent number: 4591561
    Abstract: A process for the preparation of maltopentaose is disclosed, comprising cultivating a maltopentaose-producing microorganism belonging to a genus Bacillus in a medium and isolating the thus-accumulated maltopentaose from the culture broth. A typical example of the maltopentaose-producing microorganism is Bacillus cereus NY-14. This process permits the preparation of maltopentoase without the use of amylase as in conventional methods. Maltopentaose is useful, for example, as a substrate for the determination of serum amylase.
    Type: Grant
    Filed: August 26, 1983
    Date of Patent: May 27, 1986
    Assignee: Sapporo Breweries Limited
    Inventors: Naohiro Yoshigi, Takahide Chikano, Yoshitada Mori
  • Patent number: 4569914
    Abstract: The invention relates to a process for the production of propagating material of plants by micropropagation in sterile tissue culture which comprises(a) planting sterile shoot cuttings of plants in solid nutrient medium in a suitable flask, filling up the flask with a suitable liquid nutrient medium optionally containing a growth regulator and growing the shoots in the submersed system; thereafter(b) cutting up into pieces the ramified culture thus obtained which contains a number of lateral buds and shoots, rooting the top-end shoots and planting the same after adaptation, and subjecting the cuttings prepared from the lower and middle parts of the shoot cultures to further cultivations according to step (a);and repeating steps (a) and (b) until the desired number of top-end shoots is reached.
    Type: Grant
    Filed: June 28, 1983
    Date of Patent: February 11, 1986
    Assignee: Gyogynoveny Kutato Intezet
    Inventors: Gyorgy Molnar, Peter Tetenyi, Eva Dobos, Jeno Bernath
  • Patent number: 4560657
    Abstract: A process for the production of an alkylene oxide containing at least 3 carbon atoms which comprises cultivating an ethylene-utilizing microorganism under aerobic conditions in a liquid nutrient medium containing the corresponding alkene together with assimilable sources of nitrogen and essential mineral salts, the cultivation being carried out in the presence of ethylene in a molar proportion to alkene below 1:40.
    Type: Grant
    Filed: July 20, 1983
    Date of Patent: December 24, 1985
    Assignee: Shell Oil Company
    Inventors: Jan W. Drozd, Maureen L. Bailey
  • Patent number: 4548727
    Abstract: An aqueous enzyme preparation stabilized with an ester of the formula RCOOR' where R is an alkyl of from one to three carbons or hydrogen and R' is an alkyl of from one to six carbons, the ester being in an amount of from 0.1 to about 2.5% by weight.
    Type: Grant
    Filed: October 6, 1983
    Date of Patent: October 22, 1985
    Assignee: The Drackett Company
    Inventor: Elias H. Shaer