Abstract: Described here are systems and method for using ultrasound to localize a medical device to which an active ultrasound element that can transmits ultrasound energy is attached. Doppler signal data of the medical device are acquired while the active element is transmitting acoustic energy, and the Doppler signal data are processed to detect symmetric Doppler shifts associated with the active element. The systems and methods described in the present disclosure enable tracking and display of one or more locations on or associated with the medical device.

Abstract: A T1-weighted turbo-spin-echo magnetic resonance imaging system configured to capture data associated with a subject's heart during a time period and produce MR images has a dark-blood preparation module, a data capture module, and an image reconstruction module. The dark-blood preparation module performs dark-blood preparation through double inversion during some, but not all of the heartbeats within the time period. The data capture module configured performs data readouts to capture imaging data of an imaging slice during every heartbeat in which dark-blood preparation is performed. The data capture module also performs a steady state maintenance step during every heartbeat in which dark-blood preparation is not performed in order to maintain maximum T1-weighting. The image reconstruction module configured to reconstruct a T1-weighted image based on the imaging data.

Abstract: Disclosed is an ultrasonic diagnostic apparatus including an improved actuator to compensate for a weight of an input/output device. The ultrasonic diagnostic apparatus includes a main body, an input/output device coupled to the main body and configured to receive information from a user or output information received from the main body, and a connection device to connect the main body and the input/output device, wherein the connection device includes a shaft having a shaft body, a link frame having a frame body and a shaft coupling portion extending from the frame body to be coupled with the shaft, and an actuator including a torsion spring having a first end supported by the shaft and a second end supported by the link frame, so as to compensate for a weight of the input/output device.

Abstract: Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed. In some embodiments, for example, a method may include exposing a portion of tissue that does not include a fluorescent probe to an excitation source of the tissue, wherein at least a portion of the tissue has an autofluorescence spectrum which includes wavelengths greater than 900 nm, and imaging the tissue with a detector that is sensitive to electromagnetic radiation with wavelengths greater than or equal to 900 nm. In certain other embodiments, a system comprises a fluorescent probe including a fluorescent component attached to a carrier, an excitation source, and a detector that detects a tail portion of the fluorescence of the fluorescent component. Methods associated with such a system are also disclosed.

Abstract: Systems and methods include control of a nuclear imaging scanner to acquire nuclear imaging scan data of a body, control of a computed tomography scanner to acquire computed tomography scan data of the body, determination of a scanning speed, of the nuclear imaging scanner, associated with each of a plurality of scanning coordinates based on locations of one or more internal volumes associated with radioactivity greater than a threshold level, a classification determined for each of the one or more of the internal volumes indicating a degree of clinical interest based at least in part on the radioactivity associated with the internal volume, and an attenuation coefficient map based on the computed tomography scan data, and control of the nuclear imaging scanner to scan the body over each of the scanning coordinates at the associated scanning speed.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system (100) includes a measurement apparatus (102) configured to be placed within a vascular pathway. The measurement apparatus may include a sensor array (106) comprising two or more sensor modalities. The sensor array may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, transmit and receive ultrasound signals, and rotate around a longitudinal axis of the measurement device. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: A medical information processing system in an embodiment includes processing circuitry. The processing circuitry acquires an ultrasound image including an observation target and having additional information, positional information indicating a position of an ultrasound probe in a subject at time of collection of the ultrasound image, and a reference image obtained by taking an image of a region including the observation target at a time point other than the time of collection. The processing circuitry generates, based on the positional information, correspondence information in which the ultrasound image and the reference image are associated with each other. The processing circuitry causes an output unit to output the generated correspondence information.

Abstract: An ultrasonic diagnostic imaging system is used to acquire a fetal image in a sagittal view for the performance of a nuchal translucency measurement. After a fetal image has been acquired, a zoom box is positioned over the image, encompassing a region of interest. The size of the zoom box is automatically set for the user in correspondence with gestational age or crown rump length. The system automatically tracks the region of interest within the zoom box in the presence of fetal motion in an effort to maintain the region of interest within the zoom box despite movement by the fetus.

Abstract: According to one embodiment, an ultrasonic diagnostic apparatus includes an ultrasonic probe and control circuitry. The ultrasonic probe includes a plurality of ultrasonic transducers two-dimensionally arranged along a first arrangement direction and a second arrangement direction. The control circuitry transmits first line delay data and second line delay data to the ultrasonic probe. The ultrasonic probe further comprises setting circuitry configured to set a delay amount for each of the plurality of ultrasonic transducers, by using the transmitted first line delay data and second line delay data.

Abstract: A tongue-image-based diagnostic system and a tongue-image-based diagnostic method are disclosed. The diagnostic system includes a parameter collector configured to acquire environmental parameter information; a model establishment circuitry configured to perform a training process using image training data and the environmental parameter information and establish an estimation model; and an analysis circuitry configured to analyze acquired image information using the estimation model, and generate an analysis result corresponding to the acquired image information.

Abstract: A system and method for tracking an object within a surgical field are described. A system may include a mesh of cameras distributed around the surgical field, the mesh of cameras including, for example at least three cameras. Cameras in the mesh of cameras may be in known positions or orientations relative to the surgical field or may be mobile with position or orientation to be determined by the system. The system may include a computing system communicatively coupled to the mesh of cameras, the computing system including a processor and a memory device. The computing system may be used to generate tracking data for a tracked object from images or image data taken by one or more cameras of the mesh of cameras.

Abstract: An ultrasound signal processing device includes a transmitter that causes transducers to transmit an ultrasound beam, a receiver that, based on reflected waves received by reception transducers, generates reception signal sequences corresponding to the reception transducers, and a delay-and-sum section that, for a reference observation point in a region of interest, calculates delay times of reflected wave arrival to each of the reception transducers from the reference observation point as reference delay times and generates acoustic line signals by using the reference delay times corresponding to the reception transducers. For one or more dependent observation points in the region of interest that are contiguous in a depth direction from the reference observation point, the delay-and-sum section generates acoustic line signals by applying the reference delay times corresponding to the reception transducers.

Abstract: A method for mapping shear wave velocity in biological tissues includes using an ultrasound transducer to generate mechanical excitations at a plurality of locations in a region of interest. An MRI system is used to capture a phase image of each mechanical excitation, wherein motion encoding gradients (MEGs) of the MRI system encode a propagating shear wavefront caused by the mechanical excitation. A plurality of shear wave velocity maps is generated based on the phase images, wherein each shear wave velocity map depicts velocity between adjacent propagating shear wavefronts. The shear wave speed values are combined to generate a composite shear wave velocity map of the region of interest.

Abstract: An intraoperative imaging system combines a gamma probe and an ultrasound probe. The probes are linked to provide co-registration of gamma radiation detected by the gamma probe with an image acquired by the ultrasound probe. The gamma probe has a converging collimator made of a metal block having a plurality of channels therein, which converge from an output face toward an input face. Each channel extends between and opens out at the faces such that openings at the input face have smaller cross-sectional areas than openings at the output face so that each channel tapers inwardly from the output face to the input face. The collimator has an external focal point distant from the input face. The system improves identification and localization of cancerous cells, facilitating more accurate biopsy data and more complete surgical resection. The gamma probe increases sensitivity, while maintaining spatial resolution, and increasing depth of view.

Abstract: A catheter-based ultrasound imaging system configured to provide a full circumferential 360-degree view around an intra-vascular/intra-cardiac imaging-catheter-head by generating a three-dimensional view of the tissue surrounding the imaging-head over time. The ultrasound imaging system can also provide tissue-state mapping capability. The evaluation of the vasculature and tissue characteristics include path and depth of lesions during cardiac-interventions such as ablation. The ultrasound imaging system comprises a catheter with a static or rotating sensor array tip supporting continuous circumferential rotation around its axis, connected to an ultrasound module and respective processing machinery allowing ultrafast imaging and a rotary motor that translates radial movements around a longitudinal catheter axis through a rotary torque transmitting part to rotate the sensor array-tip.

Abstract: Disclosed is a computer-implemented method for determining an ovarian follicle count and size (diameter) from a pair of 2-D transvaginal ultrasound scans.

Abstract: A system includes an acoustic probe and an acoustic imaging machine. The acoustic probe includes a substrate with first and second principal surfaces, a device insertion port with an opening passing through the substrate from the first principal surface to the second principal surface, and an array of acoustic transducer elements supported by the substrate and disposed around the device insertion port. The acoustic imaging machine may systematically vary the size and/or position of the active acoustic aperture of the probe by providing transmit signals to selected acoustic transducer elements to cause the array to transmit an acoustic probe signal to an area of interest and may record a feedback signal of the transmit signals from an acoustic receiver provided at a distal end of an interventional device passed through the device insertion port into the area of interest to find an active acoustic aperture having optimal acoustic performance.

Abstract: A Bowman's Refractive Index (BRI) for quantification of microdistortions in Bowman's Layer (BL) after Small Incision Lenticule Extraction (SMILE) is defined for a patient. BRI is summation of one or more areas of the OCT image of anterior edge of Bowman's layer, quantifies the smoothness of the Bowman's layer. The anterior edge of Bowman's layer is segmented into pixels. After segmentation, a 3rd order polynomial is curve fit to the segmented pixels of the edge of Bowman's layer. BRI is calculated by segmentation of the 3-Dimensional (3-D) OCT image. BRI acts as a marker for mechanical stability and is useful for diagnosis of disease and prognosis of treatments in human.

Abstract: A biological analysis device includes: a pulse pressure calculation unit that calculates a pulse pressure index related to a pulse pressure of a biological body; an average blood pressure calculation unit that calculates an average blood pressure index related to an average blood pressure of the biological body; and a blood pressure calculation unit that calculates a systolic blood pressure and a diastolic blood pressure in accordance with the pulse pressure index and the average blood pressure index. At least one of the pulse pressure index and the average blood pressure index is calculated in accordance with a blood flow index which is calculated from an intensity spectrum related to a frequency of light reflected and received from an inside of the biological body through radiation of a laser beam and is related to a blood flow of the biological body.

Abstract: Fresnel elevation focusing at a selected elevation angle is performed by transmitting a sequential set of Fresnel-focused ultrasound pulses, where a different Fresnel phase pattern is used for each pulse, and where the receive signals are coherently compounded. The different Fresnel patterns cause the secondary lobe energy to be reduced via averaging of variations of the pressure fields in the secondary lobe regions. In some embodiments, the method of coherently compounded Fresnel focusing is combined with coherently compounded defocused wave (e.g. plane wave or diverging wave) imaging in the azimuth direction. Each of the elevation slices are collected by changing the Fresnel patterns respectively employed when the sequence of plane waves or diverging waves are transmitted, such that the coherent compounding can benefit both planes simultaneously. Hadamard receive encoding and subsequent dynamic receive beamforming may be employed to further improve performance in the elevation direction.