Patents Examined by Richard C. Ekstrom
  • Patent number: 11326194
    Abstract: The present invention provides a method for producing dietary fiber that has a mild sweet taste by reducing sugars and provides by-products having high added values, and dietary fiber produced by the method. The dietary fiber may be produced by including: liquefying roasted dextrin; and adding enzymes including ?-amylase, ?-amylase, and maltogenic amylase to the liquefied roasted dextrin, and saccharifying the same.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: May 10, 2022
    Assignee: DAESANG CORPORATION
    Inventors: Kyoung Hee Cho, Ki Chan Kim, Kyoung Ok Park, Hak Jun Kim
  • Patent number: 11326130
    Abstract: The present invention relates to polypeptides having hexosaminidase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: May 10, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Christian B. Oehlenschlaeger, Dorotea R. Segura, Rebecca M. Vejborg, Henrik M. Geertz-Hansen, Lilian E. T. Baltsen, Jesper Salomon
  • Patent number: 11319567
    Abstract: The present disclosure relates to an ?-fucosidase having ?-(1,2), ?-(1,3), ?-(1,4), and ?-(1,6) fucosidase activity. The present disclosure also relates to the compositions comprising the ?-fucosidase, and the methods of producing and using the ?-fucosidase in cleaving ?-(1,2), ?-(1,3), ?-(1,4), and/or ?-(1,6)-linked fucoses in the glycoconjugates.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: May 3, 2022
    Assignee: ACADEMIA SINICA
    Inventors: Chi-Huey Wong, Tsung-I Tsai
  • Patent number: 11312977
    Abstract: A process for converting lignocellulosic biomass to glucose or ethanol includes subjecting the lignocellulosic biomass to a lignosulfonic acid pretreatment, wherein the lignosulfonic acid has a concentration of sulfonate groups in acid form that is greater than 0.02 mol/L and a total amount of sulfur dioxide is greater than 15 wt % based on dry weight of lignocellulosic biomass.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: April 26, 2022
    Assignee: Iogen Corporation
    Inventors: Jeffrey S. Tolan, Brian Foody, Daniel G. MacDonald
  • Patent number: 11312944
    Abstract: Compositions comprising modified recombinant polymerizing enzymes are provided, along with nucleic acid molecules encoding the modified polymerizing enzymes. In some aspects, methods of using such polymerizing enzymes to synthesize a nucleic acid molecule or to sequence a nucleic acid template are provided.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: April 26, 2022
    Assignee: Quantum-Si Incorporated
    Inventors: Brian Reed, Mohammad Wadud Bhuiya, Manjula Pandey, Jeremy Lackey, Jonathan M. Rothberg, Thomas Christian
  • Patent number: 11306301
    Abstract: The present invention relates to an isolated polypeptide having xylanase activity. Also disclosed are isolated polynucleotides encoding the polypeptide, recombinant host cells expressing the polypeptide, and methods for degrading lignocellulosic biomass using the polypeptide. He invention finds utility in the production of biofuels, in the paper and pulp industry, in clothing or leather softening, in the food industry such as baking, etc.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: April 19, 2022
    Assignees: MONAGHAN MUSHROOMS IRELAND UNLIMITED COMPANY, UNIVERSITY OF LIMERICK
    Inventors: Darragh Gaffney, Kelly Dwyer, Gary Walsh, Alison Winger
  • Patent number: 11306337
    Abstract: An industrial process using kestose hydrolases to enable the use of sugar mixtures containing 1-kestose in the industrial production of sucrose (as crystallized sugar) by providing a method for the conversion of 1-kestose into sucrose and fructose in a sugar solution, containing kestose and more than 10 mM sucrose (3 g/L), and comprising the enzymatic hydrolysis (preferably using 1-FEH enzymes—EC 3.2.1.153) of 1-kestose. The process further provides a method of producing a polypeptide having 1-kestose hydrolase activity and a composition comprising the polypeptide.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: April 19, 2022
    Assignee: CTC—Centro de Tecnologia Canavieira S.A.
    Inventors: Iuri Estrada Gouvea, Cesar Moises Camilo, Jaime Finguerut, Michael Cook
  • Patent number: 11302455
    Abstract: A method for removing iodine by using Deinococcus radiodurans having a gold nanoparticle synthesis ability is disclosed. More particularly, a method for removing radioactive iodine by adsorbing radioactive iodine onto gold nanoparticles synthesized in cells of Deinococcus radiodurans is disclosed. A recombinant microorganism having an enhanced radioactive iodine removal ability according to the present invention may selectively remove radioactive iodine present in various types of solutions at a high efficiency of 99% or higher, and thus may be very effective in removing radioactive iodine generated in large-scale hospitals, industries, nuclear facility accidents, and the like.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: April 12, 2022
    Assignee: UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATIO
    Inventor: Yong Jun Choi
  • Patent number: 11299723
    Abstract: The present invention provides engineered ?-glucosidase (BGL) enzymes, polypeptides having BGL activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. The present invention also provides compositions comprising the enzymes, and methods of using the engineered BGL enzymes to make products with ?-glucose linkages.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: April 12, 2022
    Assignee: Codexis, Inc.
    Inventors: Jack Liang, Jonathan Vroom, Stephanie Sue Galanie, Nikki Dellas, Ravi David Garcia
  • Patent number: 11279955
    Abstract: Described herein is a process of producing an organic compound, the process including: I) cultivating a genetically modified microorganism in a culture medium including sucrose as an assimilable carbon source to allow the genetically modified microorganism to produce the organic compound, and II) recovering the organic compound from the fermentation broth obtained in process step I) The genetically modified microorganism includes A) at least one genetic modification that leads to an increased activity of the enzyme encoded by the rbsK-gene, compared to the original microorganism that has not been genetically modified, and the original microorganism belongs to the family Pasteurellaceae. Also described herein are a genetically modified microorganism and the use thereof for the fermentative production of an organic compound from sucrose as an assimilable carbon source.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: March 22, 2022
    Assignee: BASF SE
    Inventors: Hartwig Schroeder, Stefan Haefner, Oskar Zelder, Christoph Wittmann, Anna Christine Schroer, Birgit Hoff, Nico Boehmer
  • Patent number: 11278610
    Abstract: The invention relates to microbial host cells engineered to produce glycoconjugate vaccines by stable integration of an acceptor protein and an oligosaccharyltransferase into the host's genome, wherein expression of the oligosaccharyltransferase is regulated.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: March 22, 2022
    Assignee: London School of Hygiene and Tropical Medicine
    Inventors: Brendan Wren, Jon Cuccui, Sherif Abouelhadid
  • Patent number: 11268113
    Abstract: Provided are a PHA-producing microorganism producing a higher molecular weight PHA and a PHA production method using the PHA-producing microorganism. A PHA-producing microorganism including a gene encoding a PHA synthase derived from genus Aeromonas, in which at least a portion of a PHA degrading enzyme gene is altered by substitution, deletion, insertion, and/or addition to reduce or eliminate activity of a PHA degrading enzyme encoded by the gene, and further a glycerol kinase activity is enhanced.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: March 8, 2022
    Assignee: KANEKA CORPORATION
    Inventors: Rina Aoki, Shunsuke Sato
  • Patent number: 11268121
    Abstract: A mutant carotenoidogenic bacterium, comprising any of genes (a)-(c) below: (a) a gene encoding a protein comprising a mutant amino acid sequence in which at least the 225th amino acid residue in the amino acid sequence of 1-deoxy-D-xylulose 5-phosphate synthase of a carotenoidogenic bacterium has been substituted with other amino acid residue; (b) a gene encoding a protein comprising a mutant amino acid sequence in which at least the 305th amino acid residue in the amino acid sequence of decaprenyl diphosphate synthase of a carotenoidogenic bacterium has been substituted with other amino acid residue; and (c) both of the genes (a) and (b) above.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: March 8, 2022
    Assignee: ENEOS CORPORATION
    Inventors: Hidetada Nagai, Wataru Sato, Toshiyuki Takahashi, Harumi Sato
  • Patent number: 11268112
    Abstract: Provided herein are recombinant fungal or bacterial cells comprising a heterologous L-lactate dehydrogenase, and processes of preparing L-lactic acid employing such cells.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: March 8, 2022
    Assignee: Lygos, Inc.
    Inventors: Andrew Jonathan Conley, Mario Ouellet, Jeffrey A. Dietrich
  • Patent number: 11261436
    Abstract: Provided is a mutant ?-glucosidase capable of more efficiently saccharifying biomass. A mutant ?-glucosidase comprising an amino acid sequence having at least 80% sequence identity to SEQ ID NO: 1, wherein the amino acid sequence has asparagine at one or more positions selected from the group consisting of positions corresponding to positions 787, 790, and 797 of SEQ ID NO: 1, and has ?-glucosidase activity.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: March 1, 2022
    Assignee: Kao Corporation
    Inventors: Hiroshi Kakeshita, Nozomu Shibata, Junichi Sumitani, Yutaro Baba, Shuji Tani, Takashi Kawaguchi
  • Patent number: 11248246
    Abstract: The present invention relates to a novel beta-glucosidase for producing glucose and a laminarioligosaccharide from seaweed. More particularly, the present invention may produce glucose from a beta-glucosidase exhibiting transglycosylase activity while showing exo-type glucanase activity against beta-glucan, as well as produce a laminarioligosaccharide by exhibiting transglycosylase activity against laminarin under different reaction conditions.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: February 15, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Kyoung Heon Kim, Dong-Hyun Kim
  • Patent number: 11248221
    Abstract: The present disclosure relates to an enzyme complex of arabinose isomerase, agarase and 3,6-anhydro galactosidase and a method for producing tagatose by degrading agar using the same. By using the enzyme complex according to the present disclosure, agar obtained from marine biomass can be degraded effectively and useful physiologically active substances such as tagatose can be obtained effectively therefrom.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: February 15, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Da-Woon Jeong, Jeong Eun Hyeon
  • Patent number: 11236375
    Abstract: The present invention relates to a novel mutant strain Clostridium thermocellum M2_15-C8 and a genetic modification process of said bacteria, wherein the mutant strain according to this invention can produce cellulase and xylanase more than the wild type. Moreover, the obtained enzymes can be used to digest the pretreated bagasse to further produce sugars effectively.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: February 1, 2022
    Assignee: PTT Global Chemical Public Company Limited
    Inventors: Chakrit Tachaapaikoon, Khanok Ratanakhanokchai, Patthra Pason, Rattiya Waeonukul, Prattana Ketbot, Wikanda Techanan, Kraileark Kittisuriyanont, Narong Kaewsuwan
  • Patent number: 11236316
    Abstract: The present invention relates to processes comprising enzymatic degradation of mannan-containing cellulosic materials for producing a hydrolyzate. The invention also relates to processes of producing a fermentation product from mannan-containing cellulosic materials.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: February 1, 2022
    Assignee: Novozymes A/S
    Inventors: Harry Showmaker, Laerke Tvedebrink Haahr, Kristian Bertel Romer M. Krogh, Johan Belfrage, Lone Baekgaard, Armindo Ribiero Gaspar, Claudia Geddes
  • Patent number: 11236368
    Abstract: An ethanologen for producing biofuel from one or more carbohydrates and reducing lactate and acetate production in a biofuel manufacturing process. The ethanologen is made by introducing into the ethanologen one or more exogenous genes required for production of a bacteriocin. The resulting ethanologen reduces lactate and acetate production by contaminant lactic acid bacteria by expression of the bacteriocin during the biofuel manufacturing process. Certain resulting ethanologens ferment sugars not naturally or not preferentially utilized by Saccharomyces cerevisiae during the manufacturing process.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: February 1, 2022
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James L. Steele, Jeffrey Broadbent, Ekkarat Phrommao