Abstract: Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.

Abstract: A system for diverting emboli within a patient can include a device that detects a presence of emboli in a first blood vessel of a patient. A compression member can be aligned, with a second blood vessel of the patient when a collar supporting the compression member is positioned at, least partially around a portion of the patient. In response to, the detection device, a controller can actuate the compression member, when the presence of emboli is detected, from an unactuated state to an actuated state in which at least a portion of the compression member (i) is closer to the second blood vessel than while in the unactuated state and (ii) compresses and limits blood flow through the second blood vessel.

Abstract: A percutaneous device including a temporary valve attached to a sheath, the sheath having an inverting section for delivery and removal thereof from a blood vessel. The sheath is inverted for delivery, housing the valve between inverted layers thereof. To deploy said valve, the sheath is everted to position the temporary valve on an outer surface thereof. The temporary valve and sheath are reversibly movable between inverted and deployed configurations. Upon eversion, the temporary valve assumes a radially expanded canopy shape having an outer diameter selected to contact the vessel wall and allow blood flow in only one direction. The temporary valve may be removed by releasing one end of the valve from the sheath, flattening the temporary valve along the longitudinal axis of the sheath. Also provided is a temporary valve system comprising a dilator for inverting and everting the sheath, said dilator being removably connected to the sheath.

Abstract: A device for occluding an atrial appendage includes a catheter-deliverable epicardial implant that is detachably secured to a delivery device. The implant includes an inflatable cuff that is positionable about the atrial appendage to an extent that, when adjustably inflated, the cuff physiologically occludes the atrial appendage. Such occlusion addresses health risks associated with atrial fibrillation and cardiac rhythm disorder.

Abstract: Embodiments of the present disclosure relate to apparatuses, systems, and methods for safely delivering and deploying an intravascular device. An apparatus for controlling an intravascular device may include a body having rotating assembly disposed through the body. The rotating assembly may be configured to hold a proximal end of an elongate mandrel. The rotating assembly may be rotationally connected to the body by a one-way bearing.

Abstract: A medical instrument according to the present disclosure includes: a contact portion configured to contact body tissue; a drive unit configured to generate drive force for causing the contact portion to contact the body tissue; and a limiter mechanism configured to impose restriction on transmission of the drive force to the contact portion, in accordance with contact force of the contact portion with respect to the body tissue. This configuration makes it possible to restrict force applied to body tissue during surgery, and to reduce failure risk, with a simple configuration.

Abstract: Devices and methods for anchoring soft tissue, tissue grafts, and the like to a bone are provided. In one example, an assembly includes a suture anchor, suture, and inserter. In another example, a method provides for reattaching soft tissue to a bone.

Abstract: A surgical manipulator includes an internal working end having an internal joint, and an external control interface linked to the internal working end for controlling the internal working end. The external control interface includes at least one lever defining a grip volume for a surgeon's hand when gripping and operating the at least one lever, and an external joint linked to the internal joint for controlling the internal joint. The external joint is positioned substantially within the grip volume.

Abstract: Release mechanism for medical device includes a bushing having a proximal end, a distal end and a channel extending therethrough. Plurality of extend proximally from the distal end are biased toward a release configuration in which engagement surfaces at distal ends thereof retract radially into the channel. A core pin insertable through the channel applies a radially expansive pressure to move the arms radially outward to a locking configuration. Engagement surfaces of the first and second arms connect to a retaining surface of a tissue treatment device containing capsule, which extends at an angle relative to the engagement surfaces selected so that a first portion of a force transmitted along an axis of the bushing moves the arms radially inward toward the release configuration before a second portion of the force exceeds a threshold level associated with the removal of a tissue treatment device from gripped tissue.

Abstract: An endoscopic clip device including a clip, a treatment instrument body comprising a sheath, an operation wire, and a distal connection portion, a sleeve accommodated inside the sheath and accommodating the connection portion in distal portion of the wire such that portion of inner diameter of the sleeve is smaller than outer diameter of the locking portion when the connection portion is drawable from the accommodation portion. The sleeve has diameter enlargement portion on distal side of the sleeve and elastically self-openable, a diameter reduction step portion on proximal side of the enlargement portion, and a sleeve body positioned on the proximal side of the enlargement portion from the step portion and having radial rigidity higher than that of the enlargement portion, and the inner diameter of the sleeve body is smaller than the outer diameter of the locking portion when the connection portion is drawable from the accommodation portion.

Abstract: An apparatus for intermittent vascular occlusion based on a personalized tourniquet pressure (PTP) includes a dual-purpose tourniquet cuff having an inflatable bladder, a sensor module having a pulsation sensor communicating pneumatically with the inflatable bladder for sensing and characterizing pressure pulsations indicative of a distal occlusion pressure (DOP) to identify a minimum pressure at which penetration of blood past the cuff is stopped, a PTP estimator responsive to the pulsation sensor for producing an estimate of a PTP, wherein the estimate of the PTP is a function of the DOP, an effector module communicating pneumatically with the inflatable bladder for maintaining pressure in the bladder near the PTP during a first time period and for maintaining pressure in the bladder near a second level of pressure during a second time period, and a controller selectively operating the inflatable bladder in conjunction with the sensor module and the effector module.

Abstract: Disclosed is an implant needle for introducing an implant into a patient. The needle has a hollow main body having a receiving portion configured to receive an implant. A taper-shaped tip portion is cut from the hollow needle main body and includes a first slant surface contiguous to an outer peripheral surface of the main body and formed at a first predetermined angle with respect to an axis of the main body. The first slant surface has an inner non-cutting edge and an outer non-cutting edge. The needle also includes a pair of second slant surfaces, each of which forms a second predetermined angle with respect to the main body axis that is larger than the first predetermined angle. Each second slant surface has an inner non-cutting edge and an outer cutting edge that is contiguous with an edge point of the tip portion. A method of manufacturing the implant needle is also disclosed.

Abstract: An epicardial implant having a positioning device that defines an open interior. The positioning device is configured to be detachably coupled with an implant delivery device such that the positioning device may be detached from the implant delivery device after the implant is in place about an atrial appendage. The positioning device has first and second sides with a distal end that couples the first and second sides. The implant includes an expandable cuff coupled with the positioning device. The positioning device is configured to selectively move the expandable cuff toward and away from an atrial appendage to position the expandable cuff in a desired position relative to the atrial appendage. The expandable cuff is expandable into at least a portion of the open interior of the positioning device to physically occlude a base of the atrial appendage following placement of the expandable cuff into the desired position.

Abstract: A connector for fluidly coupling proximal and distal tubular segments of a fluid conduit is provided. In one embodiment, the connector can include a connector body having an outer surface defining a first outer perimeter and an inner surface defining a lumen. The connector can also include a connecting device having an open configuration and a plurality of closed configurations. The connecting device can include first and second members configured to engage each other to secure the fluid conduit to the connector. The connecting device can also include a plurality of closed configurations for securing fluid conduits of different sizes.

Abstract: A suturing device includes an elongate body, a needle holder, a needle actuator mechanism, and a needle capture mechanism. The needle holder extends away from or is provided as part of a distal end portion of the elongate body. The needle holder defines a needle passage and a distal opening. The needle actuator interacts with a needle to move the needle from a retracted position toward the distal opening. The needle capture mechanism includes a needle capture member having a needle receiving portion. The needle receiving portion is capable of being positioned adjacent to and aligned with the distal opening in the needle holder to receive the associated needle exiting the needle passage through the distal opening and the needle receiving portion is capable of being offset from the distal opening so as to receive tissue between the needle capture member and the needle holder.

Abstract: A suture anchor is disclosed having an outer body with an axial bore which receives and inner body for rotation. Suture passes between the inner body and outer body and rotation of the inner body wraps the suture thereabout locking the suture thereto. Rotation of the inner body also effects radial expansion of at least a portion of the outer body to engage to anchor into a bone hole.

Abstract: Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.

Abstract: Devices and methods for treating vascular defects, such as, for example, balloon-type aneurysms, are described herein. In one embodiment, an apparatus includes an insertion portion and an expandable implant. The expandable implant is configured to be deployed in an aneurysm and is coupled to the insertion portion. The expandable implant has a first portion and a second portion coupled to the first portion. The expandable implant is movable between a first configuration in which the first portion and the second portion are substantially linearly aligned and a second configuration in which the second portion at least partially overlaps the first portion.

Abstract: A tissue displacing and fastening device is provided for manipulating and fastening tissue together. The device includes a tissue displacing elements, which displaces tissue. A fold is formed from the displaced tissue and the tissue is fastened together to secure the fold.

Abstract: A radial compression band employs a substantially rigid U-like cuff that fits over a patient's arm and then snaps onto a tightening band. A movable bubble member is positioned for movement along the band separate from the attachment to the patient and is inflatable to provide pressure to an incision or the like to accomplish hemostasis.