Patents Examined by Robert A. Wax
  • Patent number: 10329448
    Abstract: A method of preparing a coated article includes providing an article and coating a surface of the article with a polymeric composition comprising poly(glycerol sebacate). In some embodiments, the composition is a poly(glycerol sebacate) copolymer.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: June 25, 2019
    Inventors: Charles Brendan Nicholson, Jeremy J. Harris, Peter D. Gabriele
  • Patent number: 10328183
    Abstract: Various aspects of the present invention provide compositions and implantable devices including a water-insoluble therapeutic agent solubilized in a matrix of a gallate-containing compound. Other aspects provide methods of manufacturing and using such compositions and devices.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: June 25, 2019
    Inventors: John Jackson, Lindsay Stuart Machan, Kevin Letchford
  • Patent number: 10328100
    Abstract: Provided are compositions containing amorphous calcium carbonate (ACC), and at least one phosphorylated peptide which stabilizes the amorphous form of said calcium carbonate. Particularly, the peptide can be selected from crustacean proteins, also provided by the invention, namely GAP65, GAP22, GAP21, and GAP12 (also indicated herein as GAP10). The compositions are useful in pharmaceutical and nutraceutical formulations.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: June 25, 2019
    Assignee: AMORPHICAL LTD.
    Inventors: Shmuel Bentov, Amir Sagi, Amir Berman, Assaf Shechter
  • Patent number: 10328014
    Abstract: The invention relates to a cosmetic process for caring for the skin, more particularly facial skin, in particular wrinkled skin, comprising the topical application to the skin of a cosmetic composition comprising a grafted polysaccharide polymer (I) and exposure of the treated skin to light radiation, polymer (I) being of formula: PS—(CO—NH-L-X)a(COOH)b in which PS denotes the basic backbone of the polysaccharide bearing the carboxylic acid groups; L is a divalent hydrocarbon-based group containing from 1 to 20 carbon atoms; X denotes a photoactive group of azide or diazirine type; a denotes the content of COOH groups substituted with the group —NH-L-X; b denotes the content of unsubstituted free COOH groups; a being between 0.01 and 0.8; b being between 0.2 and 0.99; a+b=1 The invention also relates to the polymers (I) bearing a photoactive group X of diazirine type and to a composition comprising such a polymer in a physiologically acceptable medium.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: June 25, 2019
    Assignee: L'OREAL
    Inventor: Andrew Greaves
  • Patent number: 10327704
    Abstract: Disclosed are a dry bonding system and a wearable device for skin bonding including the dry bonding system.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: June 25, 2019
    Assignee: Research & Business Foundation Sungkyunkwan University
    Inventors: Changhyun Pang, Young Jin Park, Sang Yul Baik
  • Patent number: 10328096
    Abstract: Composition comprising chitosan for use in the prevention and/or treatment of incontinence and/or impotence in a subject undergoing prostatectomy.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: June 25, 2019
    Inventors: Thomas Freier, Stefano Geuna, Francesco Porpiglia
  • Patent number: 10328153
    Abstract: There is provided a complex comprising rifaximin and a complexing agent, wherein the complexing agent is a polyvinyl pyrrolidone (PVP) or a cyclodextrin. There is also provided a process for preparing the complex, a pharmaceutical composition including the complex and therapeutic uses of the complex.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: June 25, 2019
    Assignee: Cipla Limited
    Inventors: Maruti Ganpati Ghagare, Sunilkumar Parasnath Saroj, Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
  • Patent number: 10321686
    Abstract: A dry urine-based scent lure is provided for hunting. The lure includes an absorbent member impregnated with liquid urine, and then freeze dried to remove moisture from the host member. The urine maybe a blended mixture from different animals so as to have desired properties. The urine is concentrated and then infused into the absorbent material, which is then flash frozen, followed by freeze drying. The resulting dry scent lure is packaged so as to seal out humidity, and produce a lure with unlimited shelf life.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: June 18, 2019
    Inventors: Samuel C. Collora, Judith C. Collora
  • Patent number: 10321680
    Abstract: The present invention is directed to pesticidal mixtures comprising sabadilla alkaloids and dill seed oil and methods of controlling pests including insects and mites by application of pesticidal mixtures comprising sabadilla alkaloids and dill seed oil.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: June 18, 2019
    Inventors: Robert A. Suranyi, Donald L. Sundquist
  • Patent number: 10322092
    Abstract: Provided is a monodisperse agglomerate of a substance-containing vesicle filled with a substance at a concentration higher than conventionally possible. A mixed solution, in which a target substance is included in an aqueous medium, is mixed with a monodisperse agglomerate of a crosslinked vesicle comprising a prescribed polymer which includes a first polymer, i.e. a block copolymer having uncharged hydrophilic segments and first charged segments, and a second polymer having second charged segments carrying a charge opposite to that of the first charged segments, and in which the first polymer and/or the second polymer are/is crosslinked. As a result, the crosslinked vesicle is made to contain the target substance.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: June 18, 2019
    Inventors: Kazunori Kataoka, Akihiro Kishimura, Yasutaka Anraku, Akinori Goto
  • Patent number: 10314788
    Abstract: An oral pharmaceutical composition comprising a drug and one or more pharmaceutically acceptable excipients in a monolithic dosage form, wherein the dosage form is configured such that when the dosage form is divided into more than one piece and at least one of the pieces is administered to a subject the Cmax, AUC, and/or rate of drug released after administration is substantially the same or lower and the Tmax is higher than the Cmax, AUC, rate of drug released, and/or Tmax after administration of: (1) a comparable composition in intact dosage form of equal drug dosage of the administered at least one piece; (2) a bioequivalent drug composition in an intact dosage form of equal drug dosage to the administered at least one piece; and (3) a divided piece of a bioequivalent drug composition, wherein the divided piece comprises a drug dosage equal to the dosage of the administered piece of the oral composition. Methods of making the same and methods of using the same are also provided.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: June 11, 2019
    Inventors: Manish S. Shah, Ray J. Difalco
  • Patent number: 10314948
    Abstract: A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: June 11, 2019
    Assignee: The Spectranetics Coporation
    Inventors: Eugene T. Michal, Daniel J. Lerner, Matthew J. Pollman
  • Patent number: 10314812
    Abstract: The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: June 11, 2019
    Assignee: Humanetics Corporation
    Inventors: David C. Egberg, Michael D. Kaytor, John C. Dykstra
  • Patent number: 10314803
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising eicosapentaenoic acid and/or derivatives thereof and nicotinic acid, to methods of manufacturing such compositions, and to therapeutic methods for treating carious diseases and disorders.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: June 11, 2019
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Mehar Manku
  • Patent number: 10314941
    Abstract: Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: June 11, 2019
    Assignee: University of Iowa Research Foundation
    Inventors: Todd O. McKinley, James A. Martin, Mitchell Coleman, Tae-Hong Lim, Marc Brouillette
  • Patent number: 10307370
    Abstract: The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: June 4, 2019
    Assignee: AI Therapeutics, Inc.
    Inventors: Henri Lichenstein, Jonathan M. Rothberg, Thomas Armer, Lawrence S. Melvin, Jr.
  • Patent number: 10307396
    Abstract: A pharmaceutical composition. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 8.75-60 parts of silybin, 15-65 parts of phospholipid, 25-200 parts of a Pu'er tea extract, 6.25-40 parts of vitamin E, and 8.3-60 parts of L-carnitine. The composition can be used for treating non-alcoholic fatty liver diseases.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: June 4, 2019
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: He Sun, Xijun Yan, Naifeng Wu, Kaijing Yan, Yonghong Zhu, Shunnan Zhang, Xiaolin Bai, Xiaohui Ma, Yi He, Ting Li, Lei Li
  • Patent number: 10300142
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: May 28, 2019
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Patent number: 10292941
    Abstract: Disclosed is an adhesive patch having a support and an adhesive agent layer laminated on the support, wherein the support consists of spunlace nonwoven fabric, the adhesive agent layer comprises an SIS block copolymer and liquid paraffin, the adhesive patch has a first direction, which is a predetermined reference axis direction, and a second direction, which is orthogonal to the first direction, and a bending resistance in the first direction of the adhesive patch is 18 to 30 mm.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: May 21, 2019
    Inventors: Kentaro Nakashima, Masahiro Sato, Yasuhisa Kose, Takaaki Yoshinaga
  • Patent number: 10293079
    Abstract: This invention provides a kit for making an adhesive and/or a sealant which includes: a first composition of alginate and a multivalent cation salt at a concentration ratio (mg/ml) of 30:1 to 1:60, and a second composition of alginate and a buffer, wherein the buffer has a pH value of between 2 to 7. The invention also provides a method for making a sealant or an adhesive, by contacting the first composition and the second composition.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: May 21, 2019
    Assignee: SEALANTIS LTD.
    Inventors: Ohad Kimhi, Ronit Langzam-Sinai, Havazelet Bianco-Peled, Charles Milgrom, Rina Lev