Abstract: The invention concerns a culture medium for isolating bacteria of Listeria genus, in particular L. monocytogenes, characterized in that it comprises in a Listeria culture medium, at least a specific agent for identifying ?-mannosidase for use in solid medium.
Abstract: Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and Bcl-XL are identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing apoptosis are described, together with methods for identifying molecules that induce apoptosis through interaction with Bcl-2-family members.
Type:
Grant
Filed:
December 11, 2003
Date of Patent:
February 7, 2006
Assignee:
The Burnham Institute
Inventors:
John C. Reed, Xiao-kun Zhang, Bin Guo, Bingzhen Lin, Siva Kumar Kolluri