Abstract: The present invention provides certain novel .omega.-(alkoxycarbonyl)alkyl esters of dithiocarbanilic acid and certain aryl-substituted acids related thereto. These compounds are disclosed as immunoregulatory agents, useful in the treatment of organ transplant reject phenomena and autoimmune diseases such as arthritis.Additionally, there is described by the present invention the immunoregulatory use of .omega.-carboxyalkyl and .omega.-(alkoxycarbonyl)alkyl esters of dithiocarbanilic acid and certain aryl-substituted acids related thereto.
Type:
Grant
Filed:
November 4, 1977
Date of Patent:
December 19, 1978
Assignee:
The Upjohn Company
Inventors:
Hewitt G. Wight, Tracey G. Call, Marvin L. Mortensen