Abstract: This invention relates to 2-(heterocyclic)phenyl sulfamates which are useful as agricultural chemicals.

Abstract: Novel esters of all possible isomers and mixtures thereof of compounds of the formula ##STR1## wherein n is a number of 2,3 or 4 and R is selected from the group consisting of (a) alkyl of 1 to 12 carbon atoms optionally substituted with a member of the group consisting of cycloalkyl of 3 to 6 carbon atoms and a hydrocarbon chain of 2 to 8 carbon atoms optionally interrupted by an oxygen atom or a ketone group, (b) alkenyl and alkynyl of 3 to 8 carbon atoms, (c) cycloalkyl of 3 to 12 carbon atoms optionally containing at least one double bond and optionally substituted with at least one alkyl of 1 to 5 carbon atoms and (d) aralkyl of 7 to 12 carbon atoms optionally substituted with at least one member of the group consisting of alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, halogen and --CF.sub.3 having perfume and insecticidal properties.

Abstract: The present invention relates to the chemical products of general formula: ##STR1## in which R.sub.1 and R.sub.2 designate hydrogen; halogen, lower alkyl or lower alkoxy; R.sub.3 and R.sub.4 designate hydrogen, alkyl, alkoxy, halogen, nitro, acyl, alkylthio, alkylsulfinyl, alkylsulfonyl, a (CH.sub.2).sub.n COOR, (CH.sub.2).sub.2 CONHR, (CH.sub.2).sub.n NHCOOR or (CH.sub.2).sub.n NHCOR group; or R.sub.3 and R.sub.4 together form a heterocycle bonded to the benzene cycle; X.sub.1 is hydrogen, alkyl, hydroxymethyl or COOR and X.sub.2 is hydrogen or methyl; and to the pharmaceutically acceptable salts of said products. It also relates to a process for preparing said products and to the drugs active in particular on the cardiovascular system, containing at least one of said products.

Abstract: The present invention provides novel 13,14-didehydro-11-deoxy-11-hydroxymethyl-19-oxo-PGF.sub.1 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.

Abstract: The present invention provides novel 13,14-dihydro-11-deoxy-19-oxo-PGF.sub.2 compounds, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.

Abstract: Preparation of 5,5-Dimethyl-8-carboalkoxybicyclo [4.3.0]non-1-(6)-ene-2,7-dione by condensing dimethylpyruvic acid and 5-ono-6-heptenoic acid to produce a dibasic acid. Esterification of the acid produces a diester which is cyclized to produce the compound.

Abstract: 16-Substituted prostaglandins position and the 16-substituted-15-keto prostaglandins, said prostaglandins being useful as antisecretory agents, blood pressure lowering agents, anti-ulcerogenic agents and antihypertensive agents.

Abstract: This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

Abstract: Derivatives of 13,14-dihydro-PGE.sub.2 and 5,6; 13,14-tetrahydro-PGE.sub.2 are prepared. These new compounds not heretofore found in nature display activity as bronchodilator agents.

Abstract: Lactone and laclol intermediates for prosten-ynoic acids have been prepared.

Abstract: This invention relates to a group of cis-4,5-didehydro-11-deoxy-PG.sub.1 analogs having variable chain length, optional methyl substitution in the methyl-terminated side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including ulcer treatment, inhibition of platelet aggregation, increase of nasal patency, and labor induction at term.

Abstract: Novel compounds of the formula ##SPC1##Wherein R.sub.1 is hydrogen or methyl, R.sub. 2 is hydrogen or acetyl and the diester thereof. The compounds are useful as intermediates for preparing biologically active prostaglandins and they are useful singly as antibacterial agents.

Abstract: Substituted phenyl and naphthyl esters of PGA.sub.1, 15-alkyl-PGA.sub.1, and 15(R)-15-alkyl-PGA.sub.1, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as PGA.sub.1, 15-alkyl-PGA.sub.1, and 15(R)-15-alkyl-PGA.sub.1, and are also useful as a means for obtaining highly purified PGA.sub.1, 15-alkyl-PGA.sub.1, and 15(R)-15-alkyl-PGA.sub.1 products.

Abstract: New prostaglandin analogues having therapeutic utility of the formula: ##SPC1##(wherein B is a grouping of the formula: ##SPC2##X is --CH.sub.2 CH.sub.2 -- or cis --CH=CH--, Y is trans --CH=CH-- or, when X is --CH.sub.2 CH.sub.2 --, Y is additionally --CH.sub.2 CH.sub.2 --, A is alkyl of 1 through 3 carbon atoms, n is 4 or 5, and indicates attachment of the hydroxy radical to the carbon atom in alpha or beta configuration), and alkyl esters thereof, and cyclodextrin clathrates of such acids and esters, and non-toxic salts of such acids.